Effect of Sopoongsan on Skin Inflammation and Hyperlocomotion in Socially Isolated Mice with Atopic Dermatitis

• Published in: Evidence-based complementary and alternative medicine Vol. 2022; pp. 1 - 14
• Main Authors: Huong Nguyen, Ly Thi, Choi, Min-Jin, Shin, Heung-Mook, Yang, In-Jun
• Format: Journal Article
• Language: English
• Published: New York Hindawi 16.09.2022; Hindawi Limited
• Subjects: 1-Chloro-2,4-dinitrobenzene; Atopic dermatitis; CCL17 protein; CCL22 protein; Dermatitis; Eczema; Ethanol; Herbal medicine; Hormones; Inflammation; Interleukin 6; Leukocytes (eosinophilic); Lipopolysaccharides; Lymphocytes T; Mast cells; Medical research; Metastases; Open-field behavior; Oral administration; Prefrontal cortex; Skin; Skin diseases; Social interaction; Social interactions; Thymus; Tumor necrosis factor-α; γ-Interferon; South Korea

Psychological stress is a major exacerbating factor of atopic dermatitis (AD), a chronic inflammatory skin disease. Sopoongsan (SPS), a traditional herbal formula, has been indicated for the treatment of various skin disorders, including AD. This study investigated the effects of SPS on a 2,4-dinitr...