A Bridge Crosses the Active-Site Canyon of the Epstein–Barr Virus Nuclease with DNase and RNase Activities - Buisson, Marlyse; Géoui, Thibault; Flot, David; Tarbouriech, Nicolas; Ressing, Maaike E.; Wiertz, Emmanuel J.; Burmeister, Wim P. (Journal of molecular biology, 2009)
Keywords: Amino Acid Sequence; Animals; Catalytic Domain; Crystal structure; Crystallography, X-Ray; Cycle protein; Deoxyribonuclease; Deoxyribonucleases - chemistry; Deoxyribonucleases - genetics; Deoxyribonucleases - metabolism; DNA - chemistry; DNA - metabolism; Endonuclease; Endonucleases - chemistry; Endonucleases - genetics; Endonucleases - metabolism; Epstein-Barr virus; exonuclease; Exonucleases - chemistry; Exonucleases - genetics; Exonucleases - metabolism; Herpesvirus; Herpesvirus 4, Human - enzymology; Herpesvirus 4, Human - pathogenicity; Humans; Models, Molecular; Molecular Sequence Data; Molecular Structure; mRNA; Nuclease; Pathogens; Phages; Protein Conformation; Replication; Ribonuclease; Ribonucleases - chemistry; Ribonucleases - genetics; Ribonucleases - metabolism; Sequence Alignment; Viral Proteins - chemistry; Viral Proteins - genetics; Viral Proteins - metabolism; NPC; replication; TEV; exonuclease; HSV; GFP; NLS; KSHV; herpesvirus; EBV; crystal structure; WT; dsDNA; ssDNA; ncs; ribonuclease