Study of an antifungal medicine isavuconazole used in treatment of mold infections in China: A plain language summary

• Published in: Future microbiology Vol. 18; no. 2; pp. 87 - 91
• Main Authors: Jing, Ran, Morrissey, Ian, Xiao, Meng, Sun, Tian-Shu, Zhang, Ge, Wei, Kang, Guo, Da-Wen, Aram, Jalal A, Wang, Jeffrey, Utt, Eric A, Wang, Yao, Xu, Ying-Chun
• Format: Journal Article
• Language: English
• Published: England Future Medicine Ltd 01.01.2023
• Subjects: amphotericin B; Antifungal Agents - pharmacology; Antifungal Agents - therapeutic use; Aspergillosis - drug therapy; China; Fungi; Humans; invasive aspergillosis; invasive mold infection; invasive mucormycosis; isavuconazole; lay summary; Mucormycosis - drug therapy; Nitriles - pharmacology; Nitriles - therapeutic use; plain language summary; voriconazole; China; invasive aspergillosis; isavuconazole; voriconazole; invasive mold infection; invasive mucormycosis; amphotericin B; lay summary; plain language summary
• ISSN: 1746-0913; 1746-0921
• DOI: 10.2217/fmb-2022-0227

Molds are types of fungus that can cause sickness and death. Mold infections are increasing in China. Until 2022, medicines that can effectively treat all mold infections were still lacking in China. This summary of a study originally published in the journal . The study took place in China and tested a medicine called isavuconazole on mold samples to check if isavuconazole can be used to treat mold infections. Isavuconazole became available in China in January 2022 as a capsule (a hard gel-covered pill filled with a dose of medicine) and in June 2022 as an injection or a shot. Isavuconazole stopped the growth of most molds. Other medicines were needed at higher amounts to stop the growth of molds. Isavuconazole is another option to treat mold infections in China.