Fear-potentiated startle: Relationship to the level of state/trait anxiety in healthy subjects
The startle reflex is potentiated during experimentally induced anxiety (fear-potentiated startle). It is also increased in various anxiety disorders. The present study investigated the relationship between individual differences in fear and anxiety, and startle modulation. The eyeblink component of...
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| Published in | Biological psychiatry (1969) Vol. 33; no. 8; pp. 566 - 574 |
|---|---|
| Main Authors | , , , |
| Format | Journal Article |
| Language | English |
| Published |
United States
Elsevier Inc
15.04.1993
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| Subjects | |
| Online Access | Get full text |
| ISSN | 0006-3223 1873-2402 |
| DOI | 10.1016/0006-3223(93)90094-T |
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| Abstract | The startle reflex is potentiated during experimentally induced anxiety (fear-potentiated startle). It is also increased in various anxiety disorders. The present study investigated the relationship between individual differences in fear and anxiety, and startle modulation. The eyeblink component of the acoustic startle reflex was measured in a paradigm involving the anticipation of electric shocks in 22 healthy men who were volunteers. Each subject's fear of shock was assessed with the state portion of the State-Trait Anxiety Inventory (STAI; Spielberger 1983). Fear-potentiated startle, but not baseline startle, differed in the low and high fear subjects. The magnitude of fear-potentiated startle was larger in the high-fear group as compared to the low-fear group. The time-course of startle modulation suggested a longer duration of anticipatory anxiety in the high-fear group. Trait anxiety, which was assessed with the trait portion of the STAI, did not relate to individual differences in either baseline or fear-potentiated startle. |
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| AbstractList | The startle reflex is potentiated during experimentally induced anxiety (fear-potentiated startle). It is also increased in various anxiety disorders. The present study investigated the relationship between individual differences in fear and anxiety, and startle modulation. The eyeblink component of the acoustic startle reflex was measured in a paradigm involving the anticipation of electric shocks in 22 healthy men who were volunteers. Each subject's fear of shock was assessed with the state portion of the State-Trait Anxiety Inventory (STAI; Spielberger 1983). Fear-potentiated startle, but not baseline startle, differed in the low and high fear subjects. The magnitude of fear-potentiated startle was larger in the high-fear group as compared to the low-fear group. The time-course of startle modulation suggested a longer duration of anticipatory anxiety in the high-fear group. Trait anxiety, which was assessed with the trait portion of the STAI, did not relate to individual differences in either baseline or fear-potentiated startle.The startle reflex is potentiated during experimentally induced anxiety (fear-potentiated startle). It is also increased in various anxiety disorders. The present study investigated the relationship between individual differences in fear and anxiety, and startle modulation. The eyeblink component of the acoustic startle reflex was measured in a paradigm involving the anticipation of electric shocks in 22 healthy men who were volunteers. Each subject's fear of shock was assessed with the state portion of the State-Trait Anxiety Inventory (STAI; Spielberger 1983). Fear-potentiated startle, but not baseline startle, differed in the low and high fear subjects. The magnitude of fear-potentiated startle was larger in the high-fear group as compared to the low-fear group. The time-course of startle modulation suggested a longer duration of anticipatory anxiety in the high-fear group. Trait anxiety, which was assessed with the trait portion of the STAI, did not relate to individual differences in either baseline or fear-potentiated startle. The startle reflex is potentiated during experimentally induced anxiety (fear-potentiated startle). It is also increased in various anxiety disorders. The present study investigated the relationship between individual differences in fear and anxiety, and startle modulation. The eyeblink component of the acoustic startle reflex was measured in a paradigm involving the anticipation of electric shocks in 22 healthy men who were volunteers. Each subject's fear of shock was assessed with the state portion of the State-Trait Anxiety Inventory (STAI; Spielberger 1983). Fear-potentiated startle, but not baseline startle, differed in the low and high fear subjects. The magnitude of fear-potentiated startle was larger in the high-fear group as compared to the low-fear group. The time-course of startle modulation suggested a longer duration of anticipatory anxiety in the high-fear group. Trait anxiety, which was assessed with the trait portion of the STAI, did not relate to individual differences in either baseline or fear-potentiated startle. |
| Author | Foot, Michael Grillon, Christian Davis, Michael Ameli, Rezvan |
| Author_xml | – sequence: 1 givenname: Christian surname: Grillon fullname: Grillon, Christian organization: From the Department of Psychiatry, Yale University School of Medicine, ( New Haven, CT, USA – sequence: 2 givenname: Rezvan surname: Ameli fullname: Ameli, Rezvan organization: From the Department of Psychiatry, Yale University School of Medicine, ( New Haven, CT, USA – sequence: 3 givenname: Michael surname: Foot fullname: Foot, Michael organization: From the Department of Psychiatry, Yale University School of Medicine, ( New Haven, CT, USA – sequence: 4 givenname: Michael surname: Davis fullname: Davis, Michael organization: From the Department of Psychiatry, Yale University School of Medicine, ( New Haven, CT, USA |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/8329489$$D View this record in MEDLINE/PubMed |
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| Cites_doi | 10.1176/ajp.147.10.1308 10.1037/h0049214 10.1037/0021-843X.97.4.487 10.1037/h0060166 10.1111/j.1469-8986.1980.tb02290.x 10.1037/0033-295X.97.3.377 10.1007/BF00426027 10.3758/BF03326801 10.1037/0735-7044.105.6.826 10.1037/0021-843X.100.1.5 10.1037/h0049071 10.1037/h0025373 10.1007/BF00433036 10.1111/j.1469-8986.1969.tb02879.x 10.1111/j.1469-8986.1991.tb01999.x 10.1037/0735-7044.103.3.495 10.2466/pr0.1958.4.3.351 10.1037/0735-7044.100.6.814 10.1037/0021-843X.99.2.189 10.1111/j.1469-8986.1981.tb01832.x 10.1037/0735-7044.99.2.342 10.1037/0735-7044.100.1.11 |
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| Copyright | 1993 |
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| References | Butler, Braff, Rausch, Jenkins, Sprock, Geyer (BIB6) 1990; 147 Ornitz, Pynoos (BIB31) 1990; 147 Vrana, Lang (BIB37) 1990; 99 Davis (BIB13) 1989 Cook, Hawk, Davis, Stevenson (BIB8) 1991; 100 Lang, Bradley, Cuthbert (BIB29) 1990; 97 Breznitz (BIB4) 1967; 2 Deane (BIB16) 1969; 6 Sarter, Markovwsitsch (BIB34) 1985; 99 Greenwald, Bradley (BIB18) 1991; 27 Spielberger (BIB36) 1983 Cattell, Scheier (BIB7) 1958; 4 Klorman, Ryan (BIB27) 1980; 17 Davis (BIB10) 1979; 62 Davis (BIB12) 1989; 103 Hamm, Globisch, Cuthbert, Vaitl (BIB23) 1991; 28 Bohlin, Graham, Silverstein, Hackley (BIB3) 1981; 18 Davis, Redmond, Baraban (BIB15) 1979; 65 Vrana, Spence, Lang (BIB38) 1988; 97 Davis (BIB14) 1992 Kapp, Pascoe, Bixler (BIB26) 1984 Hitchcock, Davis (BIB25) 1991; 105 Grillon, Ameli, Woods, Merikangas, Davis (BIB20) 1991; 28 Hackley, Graham (BIB22) 1983; 11 Hitchcock, Davis (BIB24) 1986; 100 American Psychiatric Association (BIB1) 1987 Davis (BIB11) 1986; 100 Putnam (BIB32) 1990 Greenwald, Bradley, Cuthbert, Lang (BIB19) 1990; 27 Mishkin, Aggleton (BIB30) 1981 Grillon C, Ameli R, Merikangas K, Woods SW, Davis M (in press). Measuring the time-course of anticipatory anxiety using the fear-potentiated startle reflex. . Spence, Runquist (BIB35) 1958; 55 Gloor (BIB17) 1960 Lacey, Lacey (BIB28) 1974 Cuthbert, Patrick, Lang (BIB9) 1991; 28 Balaban, Losito, Simons, Graham (BIB2) 1986; 23 Brown, Kalish, Farber (BIB5) 1951; 41 Wood, Obrist (BIB39) 1968; 76 Ross (BIB33) 1961; 61 Lang (10.1016/0006-3223(93)90094-T_BIB29) 1990; 97 Cattell (10.1016/0006-3223(93)90094-T_BIB7) 1958; 4 Deane (10.1016/0006-3223(93)90094-T_BIB16) 1969; 6 Cuthbert (10.1016/0006-3223(93)90094-T_BIB9) 1991; 28 Hackley (10.1016/0006-3223(93)90094-T_BIB22) 1983; 11 Sarter (10.1016/0006-3223(93)90094-T_BIB34) 1985; 99 Davis (10.1016/0006-3223(93)90094-T_BIB13) 1989 Spielberger (10.1016/0006-3223(93)90094-T_BIB36) 1983 Putnam (10.1016/0006-3223(93)90094-T_BIB32) 1990 Bohlin (10.1016/0006-3223(93)90094-T_BIB3) 1981; 18 Greenwald (10.1016/0006-3223(93)90094-T_BIB19) 1990; 27 Davis (10.1016/0006-3223(93)90094-T_BIB10) 1979; 62 Hamm (10.1016/0006-3223(93)90094-T_BIB23) 1991; 28 Davis (10.1016/0006-3223(93)90094-T_BIB12) 1989; 103 Klorman (10.1016/0006-3223(93)90094-T_BIB27) 1980; 17 Davis (10.1016/0006-3223(93)90094-T_BIB15) 1979; 65 Ornitz (10.1016/0006-3223(93)90094-T_BIB31) 1990; 147 Brown (10.1016/0006-3223(93)90094-T_BIB5) 1951; 41 10.1016/0006-3223(93)90094-T_BIB21 Grillon (10.1016/0006-3223(93)90094-T_BIB20) 1991; 28 Lacey (10.1016/0006-3223(93)90094-T_BIB28) 1974 Spence (10.1016/0006-3223(93)90094-T_BIB35) 1958; 55 Hitchcock (10.1016/0006-3223(93)90094-T_BIB25) 1991; 105 Wood (10.1016/0006-3223(93)90094-T_BIB39) 1968; 76 American Psychiatric Association (10.1016/0006-3223(93)90094-T_BIB1) 1987 Butler (10.1016/0006-3223(93)90094-T_BIB6) 1990; 147 Davis (10.1016/0006-3223(93)90094-T_BIB14) 1992 Greenwald (10.1016/0006-3223(93)90094-T_BIB18) 1991; 27 Davis (10.1016/0006-3223(93)90094-T_BIB11) 1986; 100 Mishkin (10.1016/0006-3223(93)90094-T_BIB30) 1981 Vrana (10.1016/0006-3223(93)90094-T_BIB37) 1990; 99 Gloor (10.1016/0006-3223(93)90094-T_BIB17) 1960 Ross (10.1016/0006-3223(93)90094-T_BIB33) 1961; 61 Vrana (10.1016/0006-3223(93)90094-T_BIB38) 1988; 97 Cook (10.1016/0006-3223(93)90094-T_BIB8) 1991; 100 Balaban (10.1016/0006-3223(93)90094-T_BIB2) 1986; 23 Breznitz (10.1016/0006-3223(93)90094-T_BIB4) 1967; 2 Hitchcock (10.1016/0006-3223(93)90094-T_BIB24) 1986; 100 Kapp (10.1016/0006-3223(93)90094-T_BIB26) 1984 |
| References_xml | – volume: 27 start-page: S26 year: 1991 ident: BIB18 article-title: Fear and loathing: Startle reflex and visceral response publication-title: Psychophysiology – start-page: 109 year: 1990 end-page: 129 ident: BIB32 article-title: Great expectations: Anticipatory responses of the heart and brain publication-title: Event-Related Potentials: Basic Issues and Applications – volume: 100 start-page: 5 year: 1991 end-page: 13 ident: BIB8 article-title: Affective individual differences in startle reflex modulation publication-title: J Abnorm Psychol – volume: 97 start-page: 377 year: 1990 end-page: 395 ident: BIB29 article-title: Emotion, attention, and the startle reflex publication-title: Psychol Rev – year: 1983 ident: BIB36 publication-title: Manual for the State-Trait Anxiety Inventory – volume: 27 start-page: S36 year: 1990 ident: BIB19 article-title: The acoustic startle response indexes aversive learning publication-title: Psychophysiology – volume: 41 start-page: 317 year: 1951 end-page: 327 ident: BIB5 article-title: Conditioned fear as revealed by the magnitude of startle response to an auditory stimulus publication-title: J Exp Psychol – volume: 4 start-page: 351 year: 1958 end-page: 370 ident: BIB7 article-title: The nature of anxiety: A review of thirteen multivariate analyses comprising 814 variables publication-title: Psychol Rep – volume: 99 start-page: 189 year: 1990 end-page: 197 ident: BIB37 article-title: Fear imagery and the startle probe reflex publication-title: J Abnorm Psychol – year: 1987 ident: BIB1 publication-title: Diagnostic and Statistical Manual of Mental Disorders – volume: 100 start-page: 814 year: 1986 end-page: 824 ident: BIB11 article-title: Pharmacological and anatomical analysis of fear conditioning using the fear-potentiated startle paradigm publication-title: Behav Neurosci – volume: 147 start-page: 1308 year: 1990 end-page: 1312 ident: BIB6 article-title: Physiological evidence of exaggerated startle response in a subgroup of vietnam veterans with combat-related PTSD publication-title: Am J Psychiatry – volume: 28 start-page: S18 year: 1991 ident: BIB9 article-title: Imagery in anxiety disorder patients: visceral and startle probe responses publication-title: Psychophysiology – start-page: 473 year: 1984 end-page: 488 ident: BIB26 article-title: The amygdala: A neuroanatomical systems approach to its contribution to aversive conditioning publication-title: Neurophysiology of Memory – volume: 11 start-page: 235 year: 1983 end-page: 242 ident: BIB22 article-title: Early selective attention effects on cutaneous and acoustic blink reflexes publication-title: Physiol Psychol – volume: 28 start-page: 588 year: 1991 end-page: 595 ident: BIB20 article-title: Fear-potentiated startle in humans: Effects of anticipatory anxiety on the acoustic blink reflex publication-title: Psychophysiology – start-page: 1395 year: 1960 end-page: 1420 ident: BIB17 article-title: Amygdala publication-title: Handbook of Physiology, Sec. 1. Neurophysiology – volume: 62 start-page: 1 year: 1979 end-page: 7 ident: BIB10 article-title: Diazepam and flurazepam: Effects on conditioned fear as measured with the potentiated startle paradigm publication-title: Psychopharmacology – volume: 65 start-page: 111 year: 1979 end-page: 118 ident: BIB15 article-title: Noradrenergic agonists and antagonists: Effects on conditioned fear as measured by the potentiated startle paradigm publication-title: Psychopharmacology – volume: 18 start-page: 603 year: 1981 end-page: 611 ident: BIB3 article-title: Cardiac orienting and startle blink modification in novel and signal situations publication-title: Psychophysiology – volume: 17 start-page: 513 year: 1980 end-page: 523 ident: BIB27 article-title: Heart rate, contingent negative variation, and evoked potentials during anticipation of affective stimuli publication-title: Psychophysiology – start-page: 538 year: 1974 end-page: 564 ident: BIB28 article-title: Studies of heart rate and other bodily processes in sensorimotor behavior publication-title: Cardiovascular Psychophysiology – volume: 76 start-page: 254 year: 1968 end-page: 262 ident: BIB39 article-title: Minimal and maximal sensory intake and exercise as unconditioned stimuli in human heart-rate conditioning publication-title: J Exp Psychol – volume: 103 start-page: 495 year: 1989 end-page: 503 ident: BIB12 article-title: Sensitization of the acoustic startle reflex by footshock publication-title: Behav Neurosci – volume: 61 start-page: 265 year: 1961 end-page: 273 ident: BIB33 article-title: Conditioned fear as a function of CS-UCS and probe stimulus intervals publication-title: J Exp Psychol – volume: 28 start-page: S28 year: 1991 ident: BIB23 article-title: Startle reflex modulation in simple phobics and normals publication-title: Psychophysiology – volume: 147 start-page: 866 year: 1990 end-page: 870 ident: BIB31 article-title: Startle modulation in children with posttraumatic stress disorder publication-title: Am J Psychiatry – volume: 2 start-page: 173 year: 1967 end-page: 179 ident: BIB4 article-title: Incubation of threat: Duration of anticipation and false alarm as determinants of the fear reaction to an unavoidable frightening event publication-title: J Exp Res Personal – volume: 105 start-page: 826 year: 1991 end-page: 844 ident: BIB25 article-title: The efferent pathway of the amygdala involved in conditioned fear as measured with the fear-potentiated startle paradigm publication-title: Behav Neurosci – volume: 23 start-page: 612 year: 1986 ident: BIB2 article-title: Offline latency and amplitude scoring of the human reflex eyeblink with fortran IV (computer program abstract) publication-title: Psychophysiology – volume: 97 start-page: 487 year: 1988 end-page: 491 ident: BIB38 article-title: The startle probe response: A new measure of emotion? publication-title: J Abnorm Psychol – start-page: 52 year: 1989 end-page: 79 ident: BIB13 article-title: The role of the amygdala and its efferent projections in fear and anxiety publication-title: Psychopharmacology of Anxiety – start-page: 255 year: 1992 end-page: 305 ident: BIB14 article-title: The role of the amygdala in conditioned fear publication-title: Amygdala Neurobiological Aspects of Emotion, Memory and Mental Dysfunction – volume: 6 start-page: 17 year: 1969 end-page: 30 ident: BIB16 article-title: Cardiac activity during experimentally induced anxiety publication-title: Psychophysiology – volume: 100 start-page: 11 year: 1986 end-page: 22 ident: BIB24 article-title: Lesions of the amygdala, but not of the cerebellum or red nucleus, block conditioned fear as measured with the potentiated startle paradigm publication-title: Behav Neurosci – volume: 55 start-page: 613 year: 1958 end-page: 616 ident: BIB35 article-title: Temporal effects of conditioned fear on the eyelid reflex publication-title: J Exp Psychol – reference: Grillon C, Ameli R, Merikangas K, Woods SW, Davis M (in press). Measuring the time-course of anticipatory anxiety using the fear-potentiated startle reflex. – reference: . – volume: 99 start-page: 342 year: 1985 end-page: 380 ident: BIB34 article-title: Involvement of the amygdala in learning and memory: A critical review, with emphasis on anatomical relations publication-title: Behav Neurosci – start-page: 409 year: 1981 end-page: 422 ident: BIB30 article-title: Multiple function contributions of the amygdala in the monkey publication-title: The Amygdala Complex – volume: 147 start-page: 1308 year: 1990 ident: 10.1016/0006-3223(93)90094-T_BIB6 article-title: Physiological evidence of exaggerated startle response in a subgroup of vietnam veterans with combat-related PTSD publication-title: Am J Psychiatry doi: 10.1176/ajp.147.10.1308 – volume: 28 start-page: S18 year: 1991 ident: 10.1016/0006-3223(93)90094-T_BIB9 article-title: Imagery in anxiety disorder patients: visceral and startle probe responses publication-title: Psychophysiology – volume: 55 start-page: 613 year: 1958 ident: 10.1016/0006-3223(93)90094-T_BIB35 article-title: Temporal effects of conditioned fear on the eyelid reflex publication-title: J Exp Psychol doi: 10.1037/h0049214 – volume: 97 start-page: 487 year: 1988 ident: 10.1016/0006-3223(93)90094-T_BIB38 article-title: The startle probe response: A new measure of emotion? publication-title: J Abnorm Psychol doi: 10.1037/0021-843X.97.4.487 – start-page: 538 year: 1974 ident: 10.1016/0006-3223(93)90094-T_BIB28 article-title: Studies of heart rate and other bodily processes in sensorimotor behavior – volume: 41 start-page: 317 year: 1951 ident: 10.1016/0006-3223(93)90094-T_BIB5 article-title: Conditioned fear as revealed by the magnitude of startle response to an auditory stimulus publication-title: J Exp Psychol doi: 10.1037/h0060166 – start-page: 52 year: 1989 ident: 10.1016/0006-3223(93)90094-T_BIB13 article-title: The role of the amygdala and its efferent projections in fear and anxiety – volume: 17 start-page: 513 year: 1980 ident: 10.1016/0006-3223(93)90094-T_BIB27 article-title: Heart rate, contingent negative variation, and evoked potentials during anticipation of affective stimuli publication-title: Psychophysiology doi: 10.1111/j.1469-8986.1980.tb02290.x – volume: 97 start-page: 377 year: 1990 ident: 10.1016/0006-3223(93)90094-T_BIB29 article-title: Emotion, attention, and the startle reflex publication-title: Psychol Rev doi: 10.1037/0033-295X.97.3.377 – volume: 62 start-page: 1 year: 1979 ident: 10.1016/0006-3223(93)90094-T_BIB10 article-title: Diazepam and flurazepam: Effects on conditioned fear as measured with the potentiated startle paradigm publication-title: Psychopharmacology doi: 10.1007/BF00426027 – volume: 27 start-page: S36 year: 1990 ident: 10.1016/0006-3223(93)90094-T_BIB19 article-title: The acoustic startle response indexes aversive learning publication-title: Psychophysiology – start-page: 255 year: 1992 ident: 10.1016/0006-3223(93)90094-T_BIB14 article-title: The role of the amygdala in conditioned fear – volume: 11 start-page: 235 year: 1983 ident: 10.1016/0006-3223(93)90094-T_BIB22 article-title: Early selective attention effects on cutaneous and acoustic blink reflexes publication-title: Physiol Psychol doi: 10.3758/BF03326801 – volume: 105 start-page: 826 year: 1991 ident: 10.1016/0006-3223(93)90094-T_BIB25 article-title: The efferent pathway of the amygdala involved in conditioned fear as measured with the fear-potentiated startle paradigm publication-title: Behav Neurosci doi: 10.1037/0735-7044.105.6.826 – volume: 28 start-page: S28 year: 1991 ident: 10.1016/0006-3223(93)90094-T_BIB23 article-title: Startle reflex modulation in simple phobics and normals publication-title: Psychophysiology – year: 1983 ident: 10.1016/0006-3223(93)90094-T_BIB36 – volume: 100 start-page: 5 year: 1991 ident: 10.1016/0006-3223(93)90094-T_BIB8 article-title: Affective individual differences in startle reflex modulation publication-title: J Abnorm Psychol doi: 10.1037/0021-843X.100.1.5 – volume: 61 start-page: 265 year: 1961 ident: 10.1016/0006-3223(93)90094-T_BIB33 article-title: Conditioned fear as a function of CS-UCS and probe stimulus intervals publication-title: J Exp Psychol doi: 10.1037/h0049071 – volume: 76 start-page: 254 year: 1968 ident: 10.1016/0006-3223(93)90094-T_BIB39 article-title: Minimal and maximal sensory intake and exercise as unconditioned stimuli in human heart-rate conditioning publication-title: J Exp Psychol doi: 10.1037/h0025373 – ident: 10.1016/0006-3223(93)90094-T_BIB21 – volume: 65 start-page: 111 year: 1979 ident: 10.1016/0006-3223(93)90094-T_BIB15 article-title: Noradrenergic agonists and antagonists: Effects on conditioned fear as measured by the potentiated startle paradigm publication-title: Psychopharmacology doi: 10.1007/BF00433036 – start-page: 473 year: 1984 ident: 10.1016/0006-3223(93)90094-T_BIB26 article-title: The amygdala: A neuroanatomical systems approach to its contribution to aversive conditioning – volume: 147 start-page: 866 year: 1990 ident: 10.1016/0006-3223(93)90094-T_BIB31 article-title: Startle modulation in children with posttraumatic stress disorder publication-title: Am J Psychiatry – volume: 6 start-page: 17 year: 1969 ident: 10.1016/0006-3223(93)90094-T_BIB16 article-title: Cardiac activity during experimentally induced anxiety publication-title: Psychophysiology doi: 10.1111/j.1469-8986.1969.tb02879.x – start-page: 1395 year: 1960 ident: 10.1016/0006-3223(93)90094-T_BIB17 article-title: Amygdala – volume: 28 start-page: 588 year: 1991 ident: 10.1016/0006-3223(93)90094-T_BIB20 article-title: Fear-potentiated startle in humans: Effects of anticipatory anxiety on the acoustic blink reflex publication-title: Psychophysiology doi: 10.1111/j.1469-8986.1991.tb01999.x – volume: 2 start-page: 173 year: 1967 ident: 10.1016/0006-3223(93)90094-T_BIB4 article-title: Incubation of threat: Duration of anticipation and false alarm as determinants of the fear reaction to an unavoidable frightening event publication-title: J Exp Res Personal – volume: 103 start-page: 495 year: 1989 ident: 10.1016/0006-3223(93)90094-T_BIB12 article-title: Sensitization of the acoustic startle reflex by footshock publication-title: Behav Neurosci doi: 10.1037/0735-7044.103.3.495 – start-page: 109 year: 1990 ident: 10.1016/0006-3223(93)90094-T_BIB32 article-title: Great expectations: Anticipatory responses of the heart and brain – volume: 4 start-page: 351 year: 1958 ident: 10.1016/0006-3223(93)90094-T_BIB7 article-title: The nature of anxiety: A review of thirteen multivariate analyses comprising 814 variables publication-title: Psychol Rep doi: 10.2466/pr0.1958.4.3.351 – start-page: 409 year: 1981 ident: 10.1016/0006-3223(93)90094-T_BIB30 article-title: Multiple function contributions of the amygdala in the monkey – volume: 100 start-page: 814 year: 1986 ident: 10.1016/0006-3223(93)90094-T_BIB11 article-title: Pharmacological and anatomical analysis of fear conditioning using the fear-potentiated startle paradigm publication-title: Behav Neurosci doi: 10.1037/0735-7044.100.6.814 – volume: 99 start-page: 189 year: 1990 ident: 10.1016/0006-3223(93)90094-T_BIB37 article-title: Fear imagery and the startle probe reflex publication-title: J Abnorm Psychol doi: 10.1037/0021-843X.99.2.189 – year: 1987 ident: 10.1016/0006-3223(93)90094-T_BIB1 – volume: 18 start-page: 603 year: 1981 ident: 10.1016/0006-3223(93)90094-T_BIB3 article-title: Cardiac orienting and startle blink modification in novel and signal situations publication-title: Psychophysiology doi: 10.1111/j.1469-8986.1981.tb01832.x – volume: 99 start-page: 342 year: 1985 ident: 10.1016/0006-3223(93)90094-T_BIB34 article-title: Involvement of the amygdala in learning and memory: A critical review, with emphasis on anatomical relations publication-title: Behav Neurosci doi: 10.1037/0735-7044.99.2.342 – volume: 100 start-page: 11 year: 1986 ident: 10.1016/0006-3223(93)90094-T_BIB24 article-title: Lesions of the amygdala, but not of the cerebellum or red nucleus, block conditioned fear as measured with the potentiated startle paradigm publication-title: Behav Neurosci doi: 10.1037/0735-7044.100.1.11 – volume: 23 start-page: 612 year: 1986 ident: 10.1016/0006-3223(93)90094-T_BIB2 article-title: Offline latency and amplitude scoring of the human reflex eyeblink with fortran IV (computer program abstract) publication-title: Psychophysiology – volume: 27 start-page: S26 year: 1991 ident: 10.1016/0006-3223(93)90094-T_BIB18 article-title: Fear and loathing: Startle reflex and visceral response publication-title: Psychophysiology |
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| Snippet | The startle reflex is potentiated during experimentally induced anxiety (fear-potentiated startle). It is also increased in various anxiety disorders. The... |
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| SubjectTerms | Adolescent Adult Analysis of Variance anxiety Anxiety - physiopathology Blinking - physiology eyeblink fear Fear - physiology Habituation, Psychophysiologic - physiology Humans Male Reaction Time - physiology Reference Values Reflex, Startle - physiology Startle |
| Title | Fear-potentiated startle: Relationship to the level of state/trait anxiety in healthy subjects |
| URI | https://dx.doi.org/10.1016/0006-3223(93)90094-T https://www.ncbi.nlm.nih.gov/pubmed/8329489 https://www.proquest.com/docview/75848130 |
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