Double-Track Electrochemical Green Approach for Simultaneous Dissolution Profiling of Naproxen Sodium and Diphenhydramine Hydrochloride

• Published in: Journal of pharmaceutical and biomedical analysis Vol. 146; pp. 179 - 187
• Main Authors: Shehata, Mostafa A., Fawaz, Esraa M., El-Rahman, Mohamed K.Abd, Abdel-Moety, Ezzat M.
• Format: Journal Article
• Language: English
• Published: England Elsevier B.V 30.11.2017
• Subjects: Chemistry, Pharmaceutical - methods; Chromatography, High Pressure Liquid - methods; Diphenhydramine - chemistry; Diphenhydramine hydrochloride; Dissolution profiles; Double-track; Green analytical chemistry; In-line; Naproxen - chemistry; Naproxen sodium; Solubility; Spectrophotometry, Ultraviolet - methods; Tablets - chemistry; Diphenhydramine hydrochloride; Green analytical chemistry; Naproxen sodium; In-line; Dissolution profiles; Double-track

[Display omitted] •Novel use of ISEs for simultaneous acquisition of dissolution profiles of binary co-formulated tablets.•ISEs exceptionally provide straight forward way for dissolution testing.•No preliminary separation in reference to UV spectrophotometry and HPLC.•Promising approach to the ICH a...