Protective effects of Vitis vinifera (grapes) and one of its biologically active constituents, resveratrol, against natural and chemical toxicities: A comprehensive review

• Published in: Phytotherapy research Vol. 32; no. 11; pp. 2164 - 2190
• Main Authors: Tabeshpour, Jamshid, Mehri, Soghra, Shaebani Behbahani, Fatemeh, Hosseinzadeh, Hossein
• Format: Journal Article
• Language: English
• Published: England Wiley Subscription Services, Inc 01.11.2018
• Subjects: Animals; Antioxidants - pharmacology; Biocompatibility; Biological activity; Cancer; Carbon tetrachloride; Cardiovascular diseases; chemical toxins; Clinical trials; Constituents; enzyme activity; Fruit - chemistry; Glutathione; Glutathione peroxidase; grape seeds; Grapes; Heart diseases; Homeostasis; Humans; in vitro studies; In vivo methods and tests; Inflammatory diseases; Intoxication; Lipopolysaccharides; Malondialdehyde; Medical research; Metals; Mycotoxins; natural toxicants; natural toxins; neoplasms; Organic chemistry; Organs; Oxidation; Peroxidase; Phenolic compounds; Phenols; Phenols - pharmacology; Physiological effects; Plant Extracts - pharmacology; poisoning; Protective Agents - pharmacology; protective effect; protective effects; Resveratrol; Reviews; Seeds; Stilbenes - pharmacology; Superoxide dismutase; Toxicity; Toxins; Triptolide; Vitis - chemistry; Vitis vinifera; protective effects; chemical toxins; Vitis vinifera; natural toxins; resveratrol; grapes

Vitis vinifera (grape) is one of the “most‐produced fruit” in the world. Grape seeds are a valuable source of phenolic compounds including resveratrol (RSV). Grape and one of its biologically active constituents, RSV, exert their protective effects against different natural or chemical toxins which...