Protective effects of Vitis vinifera (grapes) and one of its biologically active constituents, resveratrol, against natural and chemical toxicities: A comprehensive review

Vitis vinifera (grape) is one of the “most‐produced fruit” in the world. Grape seeds are a valuable source of phenolic compounds including resveratrol (RSV). Grape and one of its biologically active constituents, RSV, exert their protective effects against different natural or chemical toxins which...

Full description

Saved in:
Bibliographic Details
Published inPhytotherapy research Vol. 32; no. 11; pp. 2164 - 2190
Main Authors Tabeshpour, Jamshid, Mehri, Soghra, Shaebani Behbahani, Fatemeh, Hosseinzadeh, Hossein
Format Journal Article
LanguageEnglish
Published England Wiley Subscription Services, Inc 01.11.2018
Subjects
Animals
Antioxidants - pharmacology
Biocompatibility
Biological activity
Cancer
Carbon tetrachloride
Cardiovascular diseases
chemical toxins
Clinical trials
Constituents
enzyme activity
Fruit - chemistry
Glutathione
Glutathione peroxidase
grape seeds
Grapes
Heart diseases
Homeostasis
Humans
in vitro studies
In vivo methods and tests
Inflammatory diseases
Intoxication
Lipopolysaccharides
Malondialdehyde
Medical research
Metals
Mycotoxins
natural toxicants
natural toxins
neoplasms
Organic chemistry
Organs
Oxidation
Peroxidase
Phenolic compounds
Phenols
Phenols - pharmacology
Physiological effects
Plant Extracts - pharmacology
poisoning
Protective Agents - pharmacology
protective effect
protective effects
Resveratrol
Reviews
Seeds
Stilbenes - pharmacology
Superoxide dismutase
Toxicity
Toxins
Triptolide
Vitis - chemistry
Vitis vinifera
protective effects
chemical toxins
Vitis vinifera
natural toxins
resveratrol
grapes
Online AccessGet full text

Cover

Abstract Vitis vinifera (grape) is one of the “most‐produced fruit” in the world. Grape seeds are a valuable source of phenolic compounds including resveratrol (RSV). Grape and one of its biologically active constituents, RSV, exert their protective effects against different natural or chemical toxins which could alter physiological homeostasis through a variety of mechanisms. Some of these mechanisms of actions include increase in superoxide dismutase, hemeoxygenase‐1, and glutathione peroxidase activities and reduced glutathione content and decrease in malondialdehyde (MDA) levels and activation of the nuclear erythroid2‐related factor2/ARE pathway. There are also various reports of the potential use of such compounds in preventing different ailments including cardiovascular diseases, cancer, degenerative diseases, and inflammatory disorders. Therefore, in this review, we have investigated the possible protective effects of grape and one of its biologically active constituents, RSV, on different organs' toxicity induced by natural toxins (such as mycotoxins, lipopolysaccharide, and triptolide) and chemical toxins (such as antitumors, metals, and carbon tetrachloride). There are insufficient clinical trials on this subject, so our review only includes in vivo and in vitro studies. To establish the grape beneficial effects in human intoxication, more clinical trials need to be accomplished.
AbstractList Vitis vinifera (grape) is one of the “most‐produced fruit” in the world. Grape seeds are a valuable source of phenolic compounds including resveratrol (RSV). Grape and one of its biologically active constituents, RSV, exert their protective effects against different natural or chemical toxins which could alter physiological homeostasis through a variety of mechanisms. Some of these mechanisms of actions include increase in superoxide dismutase, hemeoxygenase‐1, and glutathione peroxidase activities and reduced glutathione content and decrease in malondialdehyde (MDA) levels and activation of the nuclear erythroid2‐related factor2/ARE pathway. There are also various reports of the potential use of such compounds in preventing different ailments including cardiovascular diseases, cancer, degenerative diseases, and inflammatory disorders. Therefore, in this review, we have investigated the possible protective effects of grape and one of its biologically active constituents, RSV, on different organs' toxicity induced by natural toxins (such as mycotoxins, lipopolysaccharide, and triptolide) and chemical toxins (such as antitumors, metals, and carbon tetrachloride). There are insufficient clinical trials on this subject, so our review only includes in vivo and in vitro studies. To establish the grape beneficial effects in human intoxication, more clinical trials need to be accomplished.
Vitis vinifera (grape) is one of the “most‐produced fruit” in the world. Grape seeds are a valuable source of phenolic compounds including resveratrol (RSV). Grape and one of its biologically active constituents, RSV, exert their protective effects against different natural or chemical toxins which could alter physiological homeostasis through a variety of mechanisms. Some of these mechanisms of actions include increase in superoxide dismutase, hemeoxygenase‐1, and glutathione peroxidase activities and reduced glutathione content and decrease in malondialdehyde (MDA) levels and activation of the nuclear erythroid2‐related factor2/ARE pathway. There are also various reports of the potential use of such compounds in preventing different ailments including cardiovascular diseases, cancer, degenerative diseases, and inflammatory disorders. Therefore, in this review, we have investigated the possible protective effects of grape and one of its biologically active constituents, RSV, on different organs' toxicity induced by natural toxins (such as mycotoxins, lipopolysaccharide, and triptolide) and chemical toxins (such as antitumors, metals, and carbon tetrachloride). There are insufficient clinical trials on this subject, so our review only includes in vivo and in vitro studies. To establish the grape beneficial effects in human intoxication, more clinical trials need to be accomplished.
Vitis vinifera (grape) is one of the "most-produced fruit" in the world. Grape seeds are a valuable source of phenolic compounds including resveratrol (RSV). Grape and one of its biologically active constituents, RSV, exert their protective effects against different natural or chemical toxins which could alter physiological homeostasis through a variety of mechanisms. Some of these mechanisms of actions include increase in superoxide dismutase, hemeoxygenase-1, and glutathione peroxidase activities and reduced glutathione content and decrease in malondialdehyde (MDA) levels and activation of the nuclear erythroid2-related factor2/ARE pathway. There are also various reports of the potential use of such compounds in preventing different ailments including cardiovascular diseases, cancer, degenerative diseases, and inflammatory disorders. Therefore, in this review, we have investigated the possible protective effects of grape and one of its biologically active constituents, RSV, on different organs' toxicity induced by natural toxins (such as mycotoxins, lipopolysaccharide, and triptolide) and chemical toxins (such as antitumors, metals, and carbon tetrachloride). There are insufficient clinical trials on this subject, so our review only includes in vivo and in vitro studies. To establish the grape beneficial effects in human intoxication, more clinical trials need to be accomplished.Vitis vinifera (grape) is one of the "most-produced fruit" in the world. Grape seeds are a valuable source of phenolic compounds including resveratrol (RSV). Grape and one of its biologically active constituents, RSV, exert their protective effects against different natural or chemical toxins which could alter physiological homeostasis through a variety of mechanisms. Some of these mechanisms of actions include increase in superoxide dismutase, hemeoxygenase-1, and glutathione peroxidase activities and reduced glutathione content and decrease in malondialdehyde (MDA) levels and activation of the nuclear erythroid2-related factor2/ARE pathway. There are also various reports of the potential use of such compounds in preventing different ailments including cardiovascular diseases, cancer, degenerative diseases, and inflammatory disorders. Therefore, in this review, we have investigated the possible protective effects of grape and one of its biologically active constituents, RSV, on different organs' toxicity induced by natural toxins (such as mycotoxins, lipopolysaccharide, and triptolide) and chemical toxins (such as antitumors, metals, and carbon tetrachloride). There are insufficient clinical trials on this subject, so our review only includes in vivo and in vitro studies. To establish the grape beneficial effects in human intoxication, more clinical trials need to be accomplished.
Author Mehri, Soghra
Tabeshpour, Jamshid
Hosseinzadeh, Hossein
Shaebani Behbahani, Fatemeh
Author_xml – sequence: 1
  givenname: Jamshid
  surname: Tabeshpour
  fullname: Tabeshpour, Jamshid
  organization: Mashhad University of Medical Sciences
– sequence: 2
  givenname: Soghra
  surname: Mehri
  fullname: Mehri, Soghra
  organization: Mashhad University of Medical Sciences
– sequence: 3
  givenname: Fatemeh
  surname: Shaebani Behbahani
  fullname: Shaebani Behbahani, Fatemeh
  organization: Mashhad University of Medical Sciences
– sequence: 4
  givenname: Hossein
  orcidid: 0000-0002-3483-851X
  surname: Hosseinzadeh
  fullname: Hosseinzadeh, Hossein
  email: hosseinzadehh@mums.ac.ir
  organization: Mashhad University of Medical Sciences
BackLink https://www.ncbi.nlm.nih.gov/pubmed/30088293$$D View this record in MEDLINE/PubMed
BookMark eNqFkl1rFDEUhoNU7HYV_AUS8KZCZ83HfGS8K8UvKFikindDJnOyTckk2ySzdX-Tf9JMt1UQxasE8uQ5JyfvETpw3gFCzylZUULY600Kq5rW4hFaUNK2Ba0afoAWpK1oUVLx7RAdxXhNCGkZKZ-gQ06IEKzlC_TjIvgEKpktYNA67yL2Gn81yUS8Nc5oCBIfr4PcQHyFpRtwLj0jJpO98davjZLW7rDcW5R3MZk0gUvxBAeI22xIwdsTLNfS5EPsZJqCtHc2dQXjLMDJfzcql4X4Bp9my7gJcAUuzs4AWwO3T9FjLW2EZ_frEn159_by7ENx_un9x7PT80JxwUQBrBzYoDnTnNYAPRW66YWivSKcD5WUolLlULV84DA0nPG-kUD6pta8ZIIovkTHe-8m-JsJYupGExVYKx34KXaMijxYQUv6f5SIqq5plass0cs_0Gs_BZcfkoWsFTVpOcnUi3tq6kcYuk0wowy77uHHMrDaAyr4GAPoLg9NJuNdCtLYjpJujkSXI9HNkfjd4q8LD86_oMUevTUWdv_kuovLz3f8T1jrx8c
CitedBy_id crossref_primary_10_1007_s40618_019_01060_3
crossref_primary_10_1155_2020_6180310
crossref_primary_10_3390_antiox12091777
crossref_primary_10_2174_1871530319666191116112950
crossref_primary_10_1002_ptr_6880
crossref_primary_10_1016_j_bbrc_2024_150674
crossref_primary_10_2174_0115734064262843231120051452
crossref_primary_10_3390_nu16162651
crossref_primary_10_33462_jotaf_952108
crossref_primary_10_3389_fendo_2023_1245512
crossref_primary_10_1080_10715762_2019_1636045
crossref_primary_10_1038_s41598_021_96008_0
crossref_primary_10_1155_2020_2508952
crossref_primary_10_1016_j_fct_2023_113691
crossref_primary_10_1016_j_hermed_2022_100550
crossref_primary_10_1186_s13007_022_00978_9
crossref_primary_10_3389_fphar_2022_1011740
crossref_primary_10_3389_fphar_2021_715359
crossref_primary_10_1016_j_jphotobiol_2020_111810
crossref_primary_10_2174_0115734013314858240419052907
crossref_primary_10_1016_j_foodchem_2019_03_122
crossref_primary_10_1155_2020_3582947
crossref_primary_10_1007_s00203_022_03072_9
crossref_primary_10_1016_j_phyplu_2023_100418
crossref_primary_10_3390_jof7020142
crossref_primary_10_1007_s40199_020_00344_x
crossref_primary_10_3389_fnagi_2024_1531278
crossref_primary_10_1080_10408398_2022_2160960
crossref_primary_10_1016_S0378_4274_23_00793_2
crossref_primary_10_3390_foods13020219
crossref_primary_10_3390_toxins11110617
crossref_primary_10_1159_000520038
crossref_primary_10_1016_j_heliyon_2020_e05291
crossref_primary_10_1111_bph_15006
crossref_primary_10_1080_09603123_2022_2163985
crossref_primary_10_3390_antibiotics13080697
crossref_primary_10_1002_ptr_6469
crossref_primary_10_3390_toxins14110733
crossref_primary_10_2147_IJN_S429629
crossref_primary_10_1007_s00210_025_03945_y
crossref_primary_10_1016_j_jelechem_2021_115455
crossref_primary_10_3390_ijerph17238964
crossref_primary_10_1007_s13762_021_03541_6
crossref_primary_10_1002_ptr_7185
crossref_primary_10_1016_j_cofs_2021_05_008
crossref_primary_10_1007_s12011_022_03305_4
crossref_primary_10_3390_nu17010040
crossref_primary_10_1002_ptr_6419
crossref_primary_10_2478_intox_2020_0011
crossref_primary_10_1038_s41598_020_59489_z
crossref_primary_10_1186_s43014_024_00267_z
Cites_doi 10.1016/j.lfs.2006.11.044
10.1038/sj.bjp.0703626
10.1021/np5003143
10.1021/jf800898p
10.1016/j.fct.2012.09.023
10.1159/000074453
10.1080/08820130600745927
10.1016/j.toxrep.2015.05.004
10.1016/j.fct.2015.04.014
10.1017/S1461145712001356
10.1155/2016/6705621
10.3390/ijms11020622
10.1111/jnc.13233
10.1155/2014/617202
10.4999/uhod.10060
10.3892/mmr.2016.4928
10.1038/nrc1253
10.1039/C6FO00191B
10.1007/978-1-4612-2862-2_1
10.1016/j.pupt.2006.07.003
10.1289/ehp.866717
10.1007/s00204-013-1026-4
10.3390/nu8100656
10.1016/0167-4889(91)90031-R
10.1016/S0300-483X(00)00280-8
10.1590/S1516-89132013000300008
10.2174/0929867013373048
10.1016/S0024-3205(03)00179-6
10.18433/J30K5Q
10.1016/j.tox.2005.01.011
10.1016/j.pharep.2016.11.011
10.1177/0960327112440113
10.1016/j.fct.2016.02.003
10.3341/kjo.2010.24.2.108
10.3390/ijms17060808
10.1080/10715760802555577
10.1111/jpn.12260
10.1074/jbc.270.47.28228
10.2174/157016310791162767
10.1371/journal.pone.0060654
10.1002/mnfr.201400819
10.1262/jrd.2013-097
10.1007/s11064-015-1636-8
10.1016/j.cbi.2008.11.015
10.1016/j.ejphar.2007.03.004
10.1016/j.neures.2012.03.005
10.1016/j.reprotox.2016.05.004
10.1007/s004050100406
10.1016/j.mrgentox.2011.01.012
10.1002/hep.510310129
10.1002/ptr.2761
10.1016/S0021-9258(18)45903-0
10.1016/j.jnutbio.2012.04.005
10.1016/j.tiv.2013.12.021
10.1111/j.1440-1797.2012.01565.x
10.1111/1750-3841.12815
10.1172/JCI59755
10.1097/CMR.0b013e3283457743
10.5897/JMPR11.927
10.3390/ijerph9093354
10.1002/ptr.3200
10.3329/bjp.v10i2.22588
10.1053/gast.2001.28692
10.1016/j.fct.2009.03.043
10.1016/S0891-5849(03)00062-5
10.1016/j.fct.2012.08.040
10.1371/journal.pone.0059888
10.17795/jjnpp-27512
10.1089/ars.2007.1782
10.1371/journal.pone.0064372
10.1186/s12888-016-1174-1
10.1002/jnr.10767
10.1055/s-0035-1569452
10.1007/s10571-014-0147-5
10.1142/S0192415X08006302
10.5505/tjb.2015.22448
10.2165/00003495-200060040-00005
10.1089/cbr.2009.0635
10.1523/JNEUROSCI.23-34-10756.2003
10.1177/0748233713498437
10.1016/j.toxlet.2015.05.001
10.1016/j.jnutbio.2009.02.004
10.1016/j.fct.2008.01.003
10.1093/toxsci/kft146
10.1016/j.ejphar.2008.08.019
10.1089/152308602762197434
10.1039/c4tx00007b
10.1248/bpb.30.79
10.1007/s11064-016-1950-9
10.1186/1748-717X-7-12
10.1016/S0028-3908(98)00139-7
10.1016/j.ijporl.2011.12.021
10.1016/j.envint.2011.10.002
10.1111/j.1478-3231.2007.01615.x
10.1080/10934529.2012.672144
10.1016/j.toxlet.2017.03.012
10.1016/S0890-6238(00)00097-6
10.1016/j.taap.2011.04.022
10.4162/nrp.2014.8.2.220
10.3390/ijms12084991
10.1016/j.freeradbiomed.2010.06.002
10.1016/0277-5379(83)90177-3
10.1093/toxsci/kfm128
10.4103/0253-7613.125167
10.1016/j.cbi.2012.05.004
10.1124/pr.56.2.6
10.1002/jat.1769
10.1002/ptr.5709
10.1089/jmf.2009.0162
10.1371/journal.pone.0134768
10.1126/science.2858129
10.3892/mmr.2014.2384
10.3109/0886022X.2012.656563
10.1586/14760584.2015.1026808
10.1136/oem.60.4.237
10.1016/j.freeradbiomed.2012.02.005
10.1111/j.1742-7835.2007.00125.x
10.1177/0394632016651447
10.1002/mnfr.201000206
10.1371/journal.pone.0052164
10.1371/journal.pone.0029102
10.1371/journal.pone.0069452
10.4236/jbbs.2012.22021
10.1007/s11064-004-6883-z
10.1007/s10571-011-9752-8
10.1080/02652030500309319
10.1667/RR1190.1
10.3892/etm.2013.1381
10.5271/sjweh.159
10.1080/20024091064165
10.1016/j.taap.2014.08.011
10.1016/j.neuint.2010.11.011
10.1177/0960327112468178
10.1111/j.1753-4887.2010.00335.x
10.1002/ptr.5570
10.1016/j.toxlet.2012.04.001
10.1186/s40199-015-0112-y
10.1177/0748233714566874
10.1039/C5TX00260E
10.4103/0974-1208.138867
10.1016/j.freeradbiomed.2014.06.011
10.1016/j.fct.2009.02.006
10.1002/tox.20734
10.1211/0022357056523
10.1093/toxsci/kfn120
10.1371/journal.pone.0014575
10.1038/sj.bjp.0705688
10.1016/j.pupt.2008.04.004
10.15171/apb.2016.055
10.1098/rstb.2008.0208
10.3109/15376516.2011.556156
10.1016/j.fct.2013.03.031
10.1016/S0889-857X(05)70365-3
10.1016/j.etap.2016.07.010
10.1007/s00411-013-0461-1
10.1016/j.fct.2014.05.011
10.1111/j.1742-7843.2006.pto_497.x
10.1038/aja.2011.76
10.1016/j.etap.2009.05.013
10.1186/s12935-014-0152-2
10.1016/j.cbi.2014.12.035
10.1155/2011/703676
10.1007/s00204-003-0538-8
10.1002/ptr.5805
10.3390/ijms15011625
10.1371/journal.pone.0021565
10.3136/fstr.22.403
10.1002/jcb.25242
10.4103/0253-7613.16216
10.2174/157015911795017353
10.1007/s00204-004-0566-z
10.15537/smj.2016.4.13611
10.1007/s12011-011-9272-x
10.1016/j.ecoenv.2007.08.023
10.2165/11316640-000000000-00000
10.1002/ptr.5644
10.1007/s00420-003-0458-1
10.1007/s10534-012-9592-0
10.1016/j.fct.2013.05.030
10.1038/ki.2008.129
10.1016/j.jphotobiol.2016.03.027
10.1111/j.1745-4514.2009.00276.x
10.1186/1742-2094-8-163
10.1080/01483919008049014
10.1016/j.jchromb.2003.10.057
10.1002/jat.916
10.1124/jpet.112.194142
10.1155/2014/398285
10.1007/s10616-013-9589-8
10.1155/2014/137919
10.1139/cjpp-2015-0088
10.1016/j.neuro.2015.05.005
10.1016/j.bbadis.2006.10.019
10.18632/oncotarget.14056
10.1089/cbr.2009.0679
10.1002/mc.22099
10.1111/fcp.12205
10.3390/molecules200712250
10.1006/enrs.2002.4352
10.1002/jlcr.3368
10.1097/00002030-200304001-00004
10.1016/j.toxrep.2015.11.010
10.1002/jnr.23453
10.1002/cbf.2907
10.1097/00008877-200609000-00014
10.1016/j.biocel.2011.06.010
10.1016/j.bbadis.2015.03.009
10.18174/388693
10.3109/15376516.2014.881944
10.1093/brain/awg014
10.1177/0748233711414614
10.1016/j.etap.2015.11.018
10.1016/j.lfs.2007.06.032
10.1248/bpb.32.876
10.3390/toxins7010097
10.1016/j.fct.2012.12.052
10.1016/j.neuro.2007.03.008
10.1016/j.taap.2016.04.016
10.1016/j.fct.2016.11.035
10.1615/JEnvironPatholToxicolOncol.v20.i2.70
10.1002/em.21919
10.1111/j.1742-7843.2008.00358.x
10.1016/j.cbi.2015.10.005
10.3109/13880209.2012.729065
10.1016/0006-2952(93)90319-R
10.1002/biof.1221
10.1007/s00210-014-0994-0
10.1016/j.cbi.2005.07.004
10.4162/nrp.2015.9.1.37
10.1021/acs.chemrestox.6b00001
10.1111/1523-1747.ep12260588
10.1248/bpb.27.1459
10.1016/j.ejphar.2008.06.068
10.1016/j.ajpath.2013.08.011
10.1089/jmf.2013.2834
10.1016/j.jns.2007.06.037
10.1002/jat.1103
10.1124/mol.110.064535
10.1016/j.tig.2006.07.008
ContentType Journal Article
Copyright 2018 John Wiley & Sons, Ltd.
Copyright_xml – notice: 2018 John Wiley & Sons, Ltd.
DBID AAYXX
CITATION
CGR
CUY
CVF
ECM
EIF
NPM
7QO
7QP
7QR
7TK
7TM
8FD
FR3
K9.
P64
RC3
7X8
7S9
L.6
DOI 10.1002/ptr.6168
DatabaseName CrossRef
Medline
MEDLINE
MEDLINE (Ovid)
MEDLINE
MEDLINE
PubMed
Biotechnology Research Abstracts
Calcium & Calcified Tissue Abstracts
Chemoreception Abstracts
Neurosciences Abstracts
Nucleic Acids Abstracts
Technology Research Database
Engineering Research Database
ProQuest Health & Medical Complete (Alumni)
Biotechnology and BioEngineering Abstracts
Genetics Abstracts
MEDLINE - Academic
AGRICOLA
AGRICOLA - Academic
DatabaseTitle CrossRef
MEDLINE
Medline Complete
MEDLINE with Full Text
PubMed
MEDLINE (Ovid)
Genetics Abstracts
Biotechnology Research Abstracts
Technology Research Database
Nucleic Acids Abstracts
ProQuest Health & Medical Complete (Alumni)
Chemoreception Abstracts
Engineering Research Database
Calcium & Calcified Tissue Abstracts
Neurosciences Abstracts
Biotechnology and BioEngineering Abstracts
MEDLINE - Academic
AGRICOLA
AGRICOLA - Academic
DatabaseTitleList Genetics Abstracts
MEDLINE

CrossRef
AGRICOLA
MEDLINE - Academic
Database_xml – sequence: 1
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 2
  dbid: EIF
  name: MEDLINE
  url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search
  sourceTypes: Index Database
DeliveryMethod fulltext_linktorsrc
Discipline Medicine
Pharmacy, Therapeutics, & Pharmacology
Botany
EISSN 1099-1573
EndPage 2190
ExternalDocumentID 30088293
10_1002_ptr_6168
PTR6168
Genre reviewArticle
Journal Article
Review
GroupedDBID ---
.3N
.GA
.GJ
.Y3
05W
0R~
10A
123
1L6
1OB
1OC
1ZS
31~
33P
3SF
3WU
4.4
50Y
50Z
51W
51X
52M
52N
52O
52P
52R
52S
52T
52U
52V
52W
52X
53G
5VS
66C
702
7PT
8-0
8-1
8-3
8-4
8-5
8UM
930
A01
A03
AAESR
AAEVG
AAHBH
AAHHS
AAHQN
AAIPD
AAMNL
AANHP
AANLZ
AAONW
AASGY
AAWTL
AAXRX
AAYCA
AAYOK
AAZKR
ABCQN
ABCUV
ABEML
ABIJN
ABJNI
ABOCM
ABPVW
ABQWH
ABXGK
ACAHQ
ACBWZ
ACCFJ
ACCZN
ACGFO
ACGFS
ACGOF
ACIWK
ACMXC
ACPOU
ACPRK
ACRPL
ACSCC
ACXBN
ACXQS
ACYXJ
ADBBV
ADBTR
ADEOM
ADIZJ
ADKYN
ADMGS
ADNMO
ADOZA
ADXAS
ADZMN
AEEZP
AEGXH
AEIGN
AEIMD
AENEX
AEQDE
AEUQT
AEUYR
AFBPY
AFFPM
AFGKR
AFPWT
AFRAH
AFWVQ
AFZJQ
AHBTC
AHMBA
AIACR
AIAGR
AITYG
AIURR
AIWBW
AJBDE
ALAGY
ALMA_UNASSIGNED_HOLDINGS
ALUQN
ALVPJ
AMBMR
AMYDB
ASPBG
ATUGU
AVWKF
AZBYB
AZFZN
AZVAB
BAFTC
BDRZF
BFHJK
BHBCM
BMXJE
BROTX
BRXPI
BY8
C45
CS3
D-6
D-7
D-E
D-F
DCZOG
DPXWK
DR2
DRFUL
DRMAN
DRSTM
EBD
EBS
ECGQY
EJD
EMOBN
F00
F01
F04
F5P
FEDTE
FUBAC
G-S
G.N
GNP
GODZA
GWYGA
H.X
HF~
HGLYW
HHY
HVGLF
HZ~
IX1
J0M
JPC
KBYEO
KQQ
LATKE
LAW
LC2
LC3
LEEKS
LH4
LITHE
LOXES
LP6
LP7
LUTES
LW6
LYRES
M6Q
MEWTI
MK4
MRFUL
MRMAN
MRSTM
MSFUL
MSMAN
MSSTM
MXFUL
MXMAN
MXSTM
N04
N05
N9A
NF~
O66
O9-
OIG
OVD
P2P
P2W
P2X
P2Z
P4B
P4D
PALCI
PQQKQ
Q.N
Q11
QB0
QRW
R.K
RIWAO
RJQFR
ROL
RWI
RX1
RYL
SAMSI
SUPJJ
SV3
TEORI
UB1
V2E
V8K
W8V
W99
WBKPD
WHWMO
WIB
WIH
WIJ
WIK
WOHZO
WQJ
WRC
WUP
WVDHM
WWP
WXI
WXSBR
XG1
XV2
YCJ
ZZTAW
~IA
~KM
~WT
AAYXX
AEYWJ
AGHNM
AGQPQ
AGYGG
CITATION
CGR
CUY
CVF
ECM
EIF
NPM
7QO
7QP
7QR
7TK
7TM
8FD
AAMMB
AEFGJ
AGXDD
AIDQK
AIDYY
FR3
K9.
P64
RC3
7X8
7S9
L.6
ID FETCH-LOGICAL-c3828-e24d2df32f316eeb18f7b8c1bc033d5aa85c4d593d3ed7323b7ae0b76f34280c3
IEDL.DBID DR2
ISSN 0951-418X
1099-1573
IngestDate Fri Jul 11 18:31:32 EDT 2025
Fri Jul 11 05:25:24 EDT 2025
Sun Jul 13 05:00:43 EDT 2025
Wed Feb 19 02:33:20 EST 2025
Tue Jul 01 01:15:33 EDT 2025
Thu Apr 24 23:00:12 EDT 2025
Wed Jan 22 16:39:12 EST 2025
IsPeerReviewed true
IsScholarly true
Issue 11
Keywords protective effects
chemical toxins
Vitis vinifera
natural toxins
resveratrol
grapes
Language English
License 2018 John Wiley & Sons, Ltd.
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c3828-e24d2df32f316eeb18f7b8c1bc033d5aa85c4d593d3ed7323b7ae0b76f34280c3
Notes ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 14
ObjectType-Review-3
content type line 23
ORCID 0000-0002-3483-851X
PMID 30088293
PQID 2129860930
PQPubID 1036338
PageCount 27
ParticipantIDs proquest_miscellaneous_2189518141
proquest_miscellaneous_2085661532
proquest_journals_2129860930
pubmed_primary_30088293
crossref_citationtrail_10_1002_ptr_6168
crossref_primary_10_1002_ptr_6168
wiley_primary_10_1002_ptr_6168_PTR6168
ProviderPackageCode CITATION
AAYXX
PublicationCentury 2000
PublicationDate November 2018
2018-11-00
2018-Nov
20181101
PublicationDateYYYYMMDD 2018-11-01
PublicationDate_xml – month: 11
  year: 2018
  text: November 2018
PublicationDecade 2010
PublicationPlace England
PublicationPlace_xml – name: England
– name: Bognor Regis
PublicationSubtitle PTR
PublicationTitle Phytotherapy research
PublicationTitleAlternate Phytother Res
PublicationYear 2018
Publisher Wiley Subscription Services, Inc
Publisher_xml – name: Wiley Subscription Services, Inc
References 1983; 19
2004; 29
2004; 27
2004; 4
2008; 36
2016; 32
2016; 31
2016; 30
2008; 105
2016; 2016
2016; 303
2017; 273
2012; 17
2016; 37
2013; 59
2000; 14
2013; 55
2013; 57
2015; 135
2013; 56
2013; 51
2002; 89
2007; 1772
2013; 52
2008; 28
2016; 41
2008; 21
2012; 28
2008; 596
2010; 4
2010; 7
2008; 591
2010; 6
2016; 46
2017; 69
2013; 87
1992; 267
2015; 242
2008; 56
2009; 179
2008; 128
2015; 1852
2012; 39
2011; 4
2016; 17
2011; 6
2012; 34
2011; 5
2012; 32
2011; 8
2016; 13
2012; 31
2011; 254
2007; 15
2001; 20
2016; 11
2011; 9
2012; 50
2016; 5
2004; 55
2016; 6
2016; 7
2012; 198
2016; 3
2015; 116
2015; 236
2004; 56
2008; 46
2008; 42
2016; 29
2012; 47
1991; 1094
2016; 8
2016; 22
2014; 70
2013; 26
2013; 28
1990; 13
2013; 27
2013; 24
2007; 262
2008; 74
2007; 30
2014; 60
2008; 71
2007; 36
2014; 66
2007; 28
2017; 31
2014; 3
2012; 211
2013; 16
2010; 68
2004; 78
2014; 280
2007; 20
2014; 8
2014; 7
1996; 22
2015; 2
2010; 78
2001; 121
2017; 20
2015; 93
2006; 12
2005; 156
2015; 94
2006; 17
2015; 99
2002; 32
1985; 227
2000; 155
2003; 72
2015; 9
2015; 7
2003; 74
2003; 76
2013; 33
2013; 32
2017; 17
2017; 16
1986; 67
2013; 31
2017
2016
2014
2014; 74
2009; 3
2003; 60
2017; 100
2014; 77
2010; 11
2007; 101
2012; 122
2010; 13
2005; 210
2011; 55
2014; 24
2000; 131
2011; 59
2015; 80
2014; 28
2013; 7
2013; 8
2013; 9
2010; 21
2010; 24
2015; 81
2006; 21
2006; 22
2006; 26
2009; 364
2014; 15
2007; 9
2014; 17
2014; 10
2007; 565
2010; 34
2015; 56
2015; 59
1993; 46
2012; 342
2004; 141
2015; 54
1997; 23
1998
2003; 36
2002; 4
2014; 46
2002; 259
2014; 2014
1992
2016; 160
2007; 99
2013; 183
1995; 270
2003; 34
2010; 49
2003; 349
2007; 80
2007; 81
2009; 104
2014; 387
2003; 23
2015; 35
2015; 34
2012; 163
2009; 47
2017; 8
2012; 2012
1982; 18
2011; 13
2003; 17
2015; 229
2011; 12
2016; 71
2005; 22
2012; 52
2004; 802
2011; 721
2015; 49
2016; 90
2015; 40
2015; 41
2000; 60
2011; 21
2003; 126
2012; 69
2005; 37
2011; 27
1998; 58
2012; 63
2009; 23
2015; 15
2009; 24
2015; 14
2015; 18
1984; 82
2006; 99
2008; 19
2008; 16
2015; 10
2008; 169
2012; 147
2016; 59
2012; 76
2009; 28
2012; 73
1998; 37
2015; 23
2011; 2011
2015; 28
2012; 2
2009; 32
2007; 2007
2015; 20
2001; 8
2000; 31
2016; 63
2013; 135
2011; 43
2012; 7
2005; 57
2016; 66
2012; 9
e_1_2_7_104_1
e_1_2_7_127_1
Yang Y. (e_1_2_7_265_1) 2016; 71
e_1_2_7_60_1
e_1_2_7_83_1
e_1_2_7_191_1
Garza A. (e_1_2_7_88_1) 2006; 12
e_1_2_7_45_1
e_1_2_7_68_1
e_1_2_7_142_1
e_1_2_7_165_1
e_1_2_7_188_1
e_1_2_7_202_1
e_1_2_7_248_1
e_1_2_7_225_1
Bataineh H. N. (e_1_2_7_19_1) 2007; 28
e_1_2_7_263_1
e_1_2_7_240_1
e_1_2_7_116_1
e_1_2_7_94_1
e_1_2_7_71_1
e_1_2_7_180_1
e_1_2_7_23_1
e_1_2_7_33_1
e_1_2_7_56_1
e_1_2_7_79_1
e_1_2_7_131_1
e_1_2_7_154_1
e_1_2_7_237_1
e_1_2_7_214_1
e_1_2_7_275_1
e_1_2_7_252_1
e_1_2_7_139_1
e_1_2_7_128_1
e_1_2_7_105_1
e_1_2_7_82_1
e_1_2_7_120_1
e_1_2_7_12_1
e_1_2_7_44_1
Olas B. (e_1_2_7_178_1) 2004; 55
e_1_2_7_67_1
e_1_2_7_249_1
e_1_2_7_143_1
e_1_2_7_189_1
e_1_2_7_29_1
e_1_2_7_226_1
e_1_2_7_166_1
e_1_2_7_241_1
e_1_2_7_264_1
Kandemir F. (e_1_2_7_124_1) 2012; 163
e_1_2_7_117_1
Ragab G. M. A. (e_1_2_7_192_1) 2013; 7
e_1_2_7_70_1
e_1_2_7_93_1
e_1_2_7_181_1
e_1_2_7_24_1
e_1_2_7_32_1
e_1_2_7_55_1
Gonthier B. (e_1_2_7_90_1) 2012; 2012
Attia S. M. (e_1_2_7_14_1) 2008; 16
e_1_2_7_78_1
e_1_2_7_193_1
e_1_2_7_238_1
e_1_2_7_132_1
e_1_2_7_155_1
Melamed E. (e_1_2_7_162_1) 1982; 18
e_1_2_7_230_1
e_1_2_7_253_1
e_1_2_7_106_1
e_1_2_7_129_1
e_1_2_7_9_1
Hosseinzadeh H. (e_1_2_7_112_1) 2014
Santamaria A. B. (e_1_2_7_206_1) 2008; 128
e_1_2_7_121_1
Andreucci M. (e_1_2_7_11_1) 2014; 2014
Felton J. S. (e_1_2_7_81_1) 1986; 67
e_1_2_7_43_1
e_1_2_7_66_1
e_1_2_7_170_1
e_1_2_7_227_1
e_1_2_7_89_1
e_1_2_7_182_1
e_1_2_7_28_1
e_1_2_7_144_1
e_1_2_7_204_1
Olgun Y. (e_1_2_7_179_1) 2013; 9
e_1_2_7_242_1
e_1_2_7_118_1
Cetin A. (e_1_2_7_35_1) 2008; 19
e_1_2_7_110_1
e_1_2_7_92_1
e_1_2_7_25_1
e_1_2_7_31_1
e_1_2_7_54_1
e_1_2_7_171_1
e_1_2_7_216_1
e_1_2_7_194_1
e_1_2_7_239_1
e_1_2_7_39_1
e_1_2_7_133_1
e_1_2_7_156_1
e_1_2_7_254_1
Rezzani R. (e_1_2_7_200_1) 2006; 21
e_1_2_7_107_1
e_1_2_7_80_1
e_1_2_7_122_1
e_1_2_7_279_1
e_1_2_7_2_1
e_1_2_7_42_1
e_1_2_7_65_1
Gonzalez L. S. (e_1_2_7_91_1) 1998; 58
e_1_2_7_205_1
e_1_2_7_228_1
e_1_2_7_183_1
e_1_2_7_27_1
Sharma S. K. (e_1_2_7_215_1) 2012; 69
e_1_2_7_145_1
e_1_2_7_220_1
e_1_2_7_243_1
e_1_2_7_282_1
e_1_2_7_111_1
Clarkson T. W. (e_1_2_7_48_1) 2003; 349
Tavakkoli A. (e_1_2_7_234_1) 2017; 16
e_1_2_7_30_1
e_1_2_7_53_1
e_1_2_7_76_1
e_1_2_7_172_1
e_1_2_7_217_1
e_1_2_7_38_1
e_1_2_7_134_1
e_1_2_7_232_1
e_1_2_7_255_1
e_1_2_7_157_1
Mokni M. (e_1_2_7_168_1) 2015; 28
e_1_2_7_270_1
e_1_2_7_108_1
e_1_2_7_7_1
e_1_2_7_278_1
e_1_2_7_15_1
e_1_2_7_41_1
e_1_2_7_64_1
e_1_2_7_161_1
e_1_2_7_184_1
e_1_2_7_26_1
e_1_2_7_229_1
e_1_2_7_49_1
e_1_2_7_146_1
e_1_2_7_169_1
e_1_2_7_244_1
e_1_2_7_221_1
e_1_2_7_281_1
Hamlaoui S. (e_1_2_7_100_1) 2012; 63
e_1_2_7_52_1
Gao R. Y. (e_1_2_7_87_1) 2011; 4
e_1_2_7_75_1
Ahmed A. A. (e_1_2_7_4_1) 2007; 15
Mohammadzadeh N. (e_1_2_7_167_1) 2017; 20
e_1_2_7_150_1
e_1_2_7_196_1
e_1_2_7_37_1
e_1_2_7_173_1
e_1_2_7_218_1
Mehri S. (e_1_2_7_160_1) 2015; 18
e_1_2_7_256_1
e_1_2_7_135_1
e_1_2_7_158_1
e_1_2_7_210_1
e_1_2_7_271_1
Atmaca N. Y. E. (e_1_2_7_13_1) 2014; 2014
e_1_2_7_109_1
e_1_2_7_8_1
e_1_2_7_277_1
e_1_2_7_16_1
e_1_2_7_40_1
Jacob J. (e_1_2_7_119_1) 1998
Safa J. (e_1_2_7_203_1) 2010; 4
e_1_2_7_63_1
e_1_2_7_86_1
e_1_2_7_185_1
e_1_2_7_207_1
e_1_2_7_245_1
e_1_2_7_268_1
e_1_2_7_147_1
Hala A. (e_1_2_7_99_1) 2010; 6
e_1_2_7_222_1
e_1_2_7_260_1
Yapanoglu T. (e_1_2_7_267_1) 2015; 34
e_1_2_7_280_1
Tabeshpour J. (e_1_2_7_231_1) 2017; 20
e_1_2_7_113_1
e_1_2_7_51_1
e_1_2_7_74_1
e_1_2_7_97_1
Hamlaoui‐Gasmi S. (e_1_2_7_101_1) 2011; 5
e_1_2_7_20_1
e_1_2_7_36_1
e_1_2_7_59_1
e_1_2_7_151_1
e_1_2_7_174_1
e_1_2_7_219_1
Li S. G. (e_1_2_7_138_1) 2015; 28
Chlubek D. (e_1_2_7_46_1) 2003; 36
e_1_2_7_197_1
e_1_2_7_257_1
e_1_2_7_136_1
e_1_2_7_211_1
e_1_2_7_159_1
e_1_2_7_272_1
e_1_2_7_5_1
Yang Z. (e_1_2_7_266_1) 2013; 27
Tanriverdi G. (e_1_2_7_233_1) 2016; 31
e_1_2_7_102_1
e_1_2_7_125_1
e_1_2_7_276_1
e_1_2_7_17_1
e_1_2_7_62_1
e_1_2_7_85_1
e_1_2_7_47_1
e_1_2_7_140_1
e_1_2_7_163_1
e_1_2_7_208_1
e_1_2_7_223_1
e_1_2_7_269_1
e_1_2_7_186_1
e_1_2_7_246_1
e_1_2_7_148_1
e_1_2_7_261_1
e_1_2_7_114_1
e_1_2_7_73_1
e_1_2_7_50_1
e_1_2_7_96_1
e_1_2_7_21_1
e_1_2_7_58_1
e_1_2_7_152_1
e_1_2_7_175_1
e_1_2_7_212_1
e_1_2_7_258_1
e_1_2_7_198_1
e_1_2_7_235_1
Ramadan A. M. A. (e_1_2_7_195_1) 2011; 8
Kalantari H. (e_1_2_7_123_1) 2007; 2007
e_1_2_7_137_1
e_1_2_7_273_1
e_1_2_7_250_1
e_1_2_7_6_1
e_1_2_7_126_1
Hajizadeh Z. (e_1_2_7_98_1) 2013; 7
e_1_2_7_103_1
e_1_2_7_18_1
e_1_2_7_84_1
Abd‐Ella E. M. M. (e_1_2_7_3_1) 2016; 7
e_1_2_7_61_1
e_1_2_7_209_1
e_1_2_7_190_1
e_1_2_7_10_1
e_1_2_7_69_1
El‐Rahim A. (e_1_2_7_77_1) 2009; 3
e_1_2_7_141_1
e_1_2_7_201_1
e_1_2_7_224_1
e_1_2_7_247_1
e_1_2_7_164_1
e_1_2_7_187_1
e_1_2_7_149_1
e_1_2_7_262_1
e_1_2_7_115_1
e_1_2_7_72_1
e_1_2_7_95_1
Nutter L. M. (e_1_2_7_177_1) 1992; 267
e_1_2_7_22_1
e_1_2_7_34_1
e_1_2_7_57_1
e_1_2_7_130_1
e_1_2_7_153_1
e_1_2_7_176_1
e_1_2_7_199_1
e_1_2_7_213_1
e_1_2_7_236_1
e_1_2_7_259_1
e_1_2_7_274_1
e_1_2_7_251_1
References_xml – volume: 37
  start-page: 179
  issue: 3
  year: 2005
  end-page: 182
  article-title: Antihepatotoxic effect of grape seed oil in rat
  publication-title: Indian Journal of Pharmacology
– volume: 23
  start-page: 10756
  issue: 34
  year: 2003
  end-page: 10764
  article-title: Mechanism of toxicity in rotenone models of Parkinson's disease
  publication-title: The Journal of Neuroscience
– volume: 259
  start-page: 150
  issue: 3
  year: 2002
  end-page: 153
  article-title: Genotoxicity studies on permethrin, DEET and diazinon in primary human nasal mucosal cells
  publication-title: European Archives of Oto‐Rhino‐Laryngology
– volume: 72
  start-page: 2741
  issue: 24
  year: 2003
  end-page: 2750
  article-title: Oral administration of trans‐resveratrol to guinea pigs increases cardiac DT‐diaphorase and catalase activities, and protects isolated atria from menadione toxicity
  publication-title: Life Sciences
– volume: 89
  start-page: 101
  issue: 2
  year: 2002
  end-page: 115
  article-title: Aluminum: impacts and disease
  publication-title: Environmental Research
– volume: 122
  start-page: 1574
  issue: 4
  year: 2012
  end-page: 1583
  article-title: The mechanism underlying acetaminophen‐induced hepatotoxicity in humans and mice involves mitochondrial damage and nuclear DNA fragmentation
  publication-title: Journal of Clinical Investigation
– volume: 12
  start-page: 57
  issue: 3
  year: 2006
  end-page: 65
  article-title: Cellular mechanisms of lead neurotoxicity
  publication-title: Medical Science Monitor
– volume: 2014
  start-page: 137919
  year: 2014
  article-title: Pathogenesis of chronic hyperglycemia: From reductive stress to oxidative stress
  publication-title: Journal of Diabetes Research
– volume: 2012
  start-page: 973134
  issue: 6
  year: 2012
  article-title: Specific conditions for resveratrol neuroprotection against ethanol‐induced toxicity
  publication-title: Journal of Toxicology
– volume: 28
  start-page: 544
  issue: 4
  year: 2014
  end-page: 551
  article-title: Oxidative stress mediated by NMDA, AMPA/KA channels in acute hippocampal slices: Neuroprotective effect of resveratrol
  publication-title: Toxicology in Vitro
– volume: 29
  start-page: 823
  issue: 5
  year: 2016
  end-page: 833
  article-title: Protective capacity of resveratrol, a natural polyphenolic compound, against deoxynivalenol‐induced intestinal barrier dysfunction and bacterial translocation
  publication-title: Chemical Research in Toxicology
– volume: 60
  start-page: 895
  issue: 4
  year: 2000
  end-page: 924
  article-title: Oxaliplatin
  publication-title: Drugs
– volume: 8
  start-page: 891
  issue: 4
  year: 2011
  end-page: 899
  article-title: Resveratrol mediated protection of dacarbazine‐induced mutagenicity in mice
  publication-title: Life Science Journal
– volume: 2011
  start-page: 703676
  year: 2011
  article-title: Resveratrol regulates antioxidant status, inhibits cytokine expression and restricts apoptosis in carbon tetrachloride induced rat hepatic injury
  publication-title: Oxidative Medicine and Cellular Longevity
– volume: 69
  start-page: 933
  issue: 5
  year: 2012
  end-page: 937
  article-title: Hepatoprotective activity of Vitis vinifera root extract against carbon tetrachloride‐induced liver damage in rats
  publication-title: Acta Poloniae Pharmaceutica
– volume: 99
  start-page: 1094
  issue: 6
  year: 2015
  end-page: 1104
  article-title: Effect of dietary resveratrol in ameliorating aflatoxin B1‐induced changes in broiler birds
  publication-title: Journal of Animal Physiology and Animal Nutrition
– start-page: 1
  year: 1992
  end-page: 155
– volume: 32
  start-page: 1
  issue: 1
  year: 2002
  end-page: 42
  article-title: The nature of chromosomal aberrations detected in humans exposed to benzene
  publication-title: Critical Reviews in Toxicology
– volume: 74
  start-page: 252
  issue: 9
  year: 2014
  end-page: 262
  article-title: Calorie restriction combined with resveratrol induces autophagy and protects 26‐month‐old rat hearts from doxorubicin‐induced toxicity
  publication-title: Free Radical Biology and Medicine
– volume: 8
  start-page: 220
  issue: 2
  year: 2014
  end-page: 226
  article-title: Protective effect of resveratrol on arsenic trioxide‐induced nephrotoxicity in rats
  publication-title: Nutrition Research and Practice
– volume: 198
  start-page: 38
  issue: 1
  year: 2012
  end-page: 48
  article-title: Modulation of arsenic‐induced epidermal growth factor receptor pathway signalling by resveratrol
  publication-title: Chemico‐Biological Interactions
– volume: 364
  start-page: 2063
  issue: 1526
  year: 2009
  end-page: 2078
  article-title: Human body burdens of chemicals used in plastic manufacture
  publication-title: Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
– volume: 32
  start-page: 1486
  issue: 8
  year: 2016
  end-page: 1494
  article-title: Protective effects of grape seed extract on cadmium‐induced testicular damage, apoptosis, and endothelial nitric oxide synthases expression in rats
  publication-title: Toxicology and Industrial Health
– volume: 71
  start-page: 301
  issue: 1
  year: 2008
  end-page: 308
  article-title: Protective effect of resveratrol against naphthalene‐induced oxidative stress in mice
  publication-title: Ecotoxicology and Environmental Safety
– volume: 179
  start-page: 131
  issue: 2
  year: 2009
  end-page: 144
  article-title: Resveratrol‐mediated chemoprevention of diethylnitrosamine‐initiated hepatocarcinogenesis: Inhibition of cell proliferation and induction of apoptosis
  publication-title: Chemico‐Biological Interactions
– volume: 7
  start-page: 52164
  issue: 12
  year: 2012
  article-title: Resveratrol prevents ammonia toxicity in astroglial cells
  publication-title: PLoS One
– volume: 93
  start-page: 149
  issue: 1
  year: 2015
  end-page: 156
  article-title: Resveratrol protects against homocysteine‐induced cell damage via cell stress response in neuroblastoma cells
  publication-title: Journal of Neuroscience Research
– volume: 76
  start-page: 556
  issue: 8
  year: 2003
  end-page: 576
  article-title: Naphthalene‐an environmental and occupational toxicant
  publication-title: International Archives of Occupational and Environmental Health
– volume: 802
  start-page: 217
  issue: 1
  year: 2004
  end-page: 223
  article-title: Phytoalexin resveratrol attenuates the mutagenicity of the heterocyclic amines 2‐amino‐1‐methyl‐6‐phenylimidazo[4,5‐b] pyridine and 2‐amino‐3,8‐dimethylimidazo[4,5‐f]quinoxaline
  publication-title: Journal of Chromatography B
– volume: 3
  start-page: 197
  issue: 3
  year: 2014
  end-page: 204
  article-title: The mutagenic effects of 2‐amino‐1‐methyl‐6‐phenylimidazo[4,5‐b] pyridine in Muta [trade mark sign] Mouse colon is attenuated by resveratrol
  publication-title: Toxicological Research
– volume: 9
  start-page: 145
  issue: 2
  year: 2013
  end-page: 152
  article-title: Molecular mechanisms of protective effect of resveratrol against cisplatinium induced ototoxicity
  publication-title: The Journal of International Advanced Otology
– volume: 37
  start-page: 1187
  issue: 10‐11
  year: 1998
  end-page: 1204
  article-title: Neuropharmacology of AMPA and kainate receptors
  publication-title: Neuropharmacology
– volume: 105
  start-page: 24
  issue: 1
  year: 2008
  end-page: 32
  article-title: Liver is a target of arsenic carcinogenesis
  publication-title: Toxicological Sciences
– volume: 41
  start-page: 2367
  issue: 9
  year: 2016
  end-page: 2379
  article-title: Resveratrol attenuates Aβ25–35 caused neurotoxicity by inducing autophagy through the TyrRS‐PARP1‐SIRT1 signaling pathway
  publication-title: Neurochemical Research
– volume: 387
  start-page: 837
  issue: 9
  year: 2014
  end-page: 848
  article-title: Effects of the compounds resveratrol, rutin, quercetin, and quercetin nanoemulsion on oxaliplatin‐induced hepatotoxicity and neurotoxicity in mice
  publication-title: Naunyn‐Schmiedeberg's Archives of Pharmacology
– volume: 24
  start-page: 713
  issue: 4
  year: 2013
  end-page: 724
  article-title: Chemoprevention of benzo (a)pyrene‐induced colon polyps in ApcMin mice by resveratrol
  publication-title: The Journal of Nutritional Biochemistry
– volume: 57
  start-page: 1043
  issue: 8
  year: 2005
  end-page: 1051
  article-title: Amelioration of doxorubicin‐induced myocardial oxidative stress and immunosuppression by grape seed proanthocyanidins in tumour‐bearing mice
  publication-title: Journal of Pharmacy and Pharmacology
– volume: 56
  start-page: 333
  issue: 3
  year: 2015
  end-page: 346
  article-title: Resveratrol protects against arsenic trioxide‐induced oxidative damage through maintenance of glutathione homeostasis and inhibition of apoptotic progression
  publication-title: Environmental and Molecular Mutagenesis
– volume: 49
  start-page: 800
  issue: 5
  year: 2010
  end-page: 813
  article-title: Mechanism for the protective effect of resveratrol against oxidative stress‐induced neuronal death
  publication-title: Free Radical Biology and Medicine
– volume: 2
  start-page: 176
  year: 2012
  end-page: 184
  article-title: Grape seed extract ( ) alleviate neurotoxicity and hepatotoxicity induced by lead acetate in male albino rats
  publication-title: Journal of Behavioral and Brain Science
– volume: 10
  start-page: 366
  issue: 2
  year: 2015
  end-page: 376
  article-title: Resveratrol inhibits cadmium induced neuronal apoptosis by modulating calcium signalling pathway via regulation of MAPK/mTOR network
  publication-title: Bangladesh Journal of Pharmacology
– volume: 1772
  start-page: 48
  issue: 1
  year: 2007
  end-page: 59
  article-title: Carcinogen‐induced early molecular events and its implication in the initiation of chemical hepatocarcinogenesis in rats: Chemopreventive role of vanadium on this process
  publication-title: Biochimica et Biophysica Acta
– volume: 59
  start-page: 8
  issue: 9
  year: 2013
  end-page: 17
  article-title: Dual role of resveratrol in modulation of genotoxicity induced by sodium arsenite via oxidative stress and apoptosis
  publication-title: Food and Chemical Toxicology
– volume: 68
  start-page: 656
  issue: 11
  year: 2010
  end-page: 670
  article-title: Biomedical effects of grape products
  publication-title: Nutrition Reviews
– volume: 47
  start-page: 1168
  issue: 6
  year: 2009
  end-page: 1175
  article-title: Propolis protection from reproductive toxicity caused by aluminium chloride in male rats
  publication-title: Food and Chemical Toxicology
– volume: 15
  start-page: 1625
  issue: 1
  year: 2014
  end-page: 1646
  article-title: Resveratrol partially prevents rotenone‐induced neurotoxicity in dopaminergic SH‐SY5Y cells through induction of heme oxygenase‐1 dependent autophagy
  publication-title: International Journal of Molecular Sciences
– volume: 66
  start-page: 339
  issue: 7
  year: 2016
  end-page: 344
  article-title: Grape juice concentrate protects rat liver against cadmium intoxication: Histopathology, cytochrome C and metalloproteinases expression
  publication-title: Drug Research
– volume: 6
  start-page: 423
  issue: 3
  year: 2016
  end-page: 433
  article-title: Cardioprotective effect of grape seed extract on chronic doxorubicin‐induced cardiac toxicity in wistar rats
  publication-title: Advanced Pharmaceutical Bulletin
– volume: 46
  start-page: 51
  issue: 1
  year: 2014
  end-page: 56
  article-title: Protective effects of resveratrol against di‐n buthyl phthalate induced toxicity in ductus epididymis and ductus deferens in rats
  publication-title: Indian Journal of Pharmacology
– volume: 163
  start-page: 539
  issue: 11
  year: 2012
  end-page: 545
  article-title: Protective antioxidant effects of grape seed extract in a cisplatin‐induced hepatotoxicity model in rabbits
  publication-title: Revue de Médecine Vétérinaire
– volume: 43
  start-page: 1469
  issue: 10
  year: 2011
  end-page: 1482
  article-title: The roles of ER stress and P450 2E1 in CCl(4)‐induced steatosis
  publication-title: The International Journal of Biochemistry & Cell Biology
– volume: 13
  start-page: 3101
  issue: 4
  year: 2016
  end-page: 3109
  article-title: Protective effect of grape seed extract against cadmium‐induced testicular dysfunction
  publication-title: Molecular Medicine Reports
– volume: 23
  start-page: 883
  issue: 4
  year: 1997
  end-page: 915
  article-title: Methotrexate hepatotoxicity
  publication-title: Rheumatic Diseases Clinics of North America
– volume: 227
  start-page: 1496
  issue: 4693
  year: 1985
  end-page: 1499
  article-title: Alterations in L‐glutamate binding in Alzheimer's and Huntington's diseases
  publication-title: Science
– volume: 591
  start-page: 96
  issue: 1‐3
  year: 2008
  end-page: 101
  article-title: Catechin and proanthocyanidin B4 from grape seeds prevent doxorubicin‐induced toxicity in cardiomyocytes
  publication-title: European Journal of Pharmacology
– volume: 78
  start-page: 525
  issue: 9
  year: 2004
  end-page: 532
  article-title: Protective effect of resveratrol against 6‐hydroxydopamine‐induced impairment of renal p‐aminohippurate transport
  publication-title: Archives of Toxicology
– volume: 99
  start-page: 366
  issue: 2
  year: 2007
  end-page: 394
  article-title: Perfluoroalkyl acids: A review of monitoring and toxicological findings
  publication-title: Toxicological Sciences
– volume: 20
  start-page: 127
  issue: 2
  year: 2001
  end-page: 131
  article-title: Transplacental carcinogenic potential of the carbamate fungicide mancozeb
  publication-title: Journal of Environmental Pathology, Toxicology and Oncology
– volume: 8
  start-page: 64372
  issue: 5
  year: 2013
  article-title: Resveratrol protects C6 astrocyte cell line against hydrogen peroxide‐induced oxidative stress through heme oxygenase 1
  publication-title: PLoS One
– volume: 21
  start-page: 482
  issue: 6
  year: 2010
  end-page: 489
  article-title: Protective effects of pinostilbene, a resveratrol methylated derivative, against 6‐hydroxydopamine‐induced neurotoxicity in SH‐SY5Y cells
  publication-title: The Journal of Nutritional Biochemistry
– volume: 56
  start-page: 185
  issue: 2
  year: 2004
  end-page: 229
  article-title: Anthracyclines: Molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity
  publication-title: Pharmacological Reviews
– volume: 70
  start-page: 191
  issue: 8
  year: 2014
  end-page: 197
  article-title: Protective effect of resveratrol on sodium fluoride‐induced oxidative stress, hepatotoxicity and neurotoxicity in rats
  publication-title: Food and Chemical Toxicology
– volume: 8
  start-page: 60654
  issue: 4
  year: 2013
  article-title: Resveratrol confers protection against rotenone‐induced neurotoxicity by modulating myeloperoxidase levels in glial cells
  publication-title: PLoS One
– volume: 2007
  start-page: 87
  issue: 02
  year: 2007
  end-page: 93
  article-title: Protective effects of hydroalcoholic extract of red grape seed ( ) in nephrotoxicity induced by amikacin in mice
  publication-title: Jundishapur Journal of Natural Pharmaceutical Products
– volume: 34
  start-page: 973
  issue: 5
  year: 2015
  end-page: 979
  article-title: The comparison of resveratrol and N‐acetylcysteine on the oxidative kidney damage caused by high dose paracetamol
  publication-title: Latin American Journal of Pharmacy
– volume: 80
  start-page: H869
  issue: 4
  year: 2015
  end-page: H874
  article-title: Evaluation of protective effect of freeze‐dried strawberry, grape, and blueberry powder on acrylamide toxicity in mice
  publication-title: Journal of Food Science
– volume: 30
  start-page: 79
  issue: 1
  year: 2007
  end-page: 83
  article-title: Gentamicin‐induced nephrotoxicity in rats ameliorated and healing effects of resveratrol
  publication-title: Biological and Pharmaceutical Bulletin
– volume: 7
  start-page: 81
  issue: 3
  year: 2013
  end-page: 81
  article-title: Protective effect of black grapes seed hydroalcholic extract against fluoxetine‐induced embryo toxicity in male mice
  publication-title: International Journal of Fertility & Sterility
– volume: 56
  start-page: 6777
  year: 2008
  end-page: 6784
  article-title: Grapes and human health: A perspective
  publication-title: Journal of Agricultural and Food Chemistry
– volume: 242
  start-page: 179
  issue: 18
  year: 2015
  end-page: 193
  article-title: Cadmium induced cardiac oxidative stress in rats and its attenuation by GSP through the activation of Nrf2 signaling pathway
  publication-title: Chemico‐Biological Interactions
– volume: 229
  start-page: 17
  issue: 3
  year: 2015
  end-page: 25
  article-title: Reversal of radiocontrast medium toxicity in human renal proximal tubular cells by white grape juice extract
  publication-title: Chemico‐Biological Interactions
– volume: 59
  start-page: 456
  issue: 4
  year: 2011
  end-page: 464
  article-title: 13N as a tracer for studying glutamate metabolism
  publication-title: Neurochemistry International
– volume: 29
  start-page: 398
  issue: 3
  year: 2016
  end-page: 407
  article-title: Neuroprotective effect of grape seed extract against cadmium toxicity in male albino rats
  publication-title: International Journal of Immunopathology and Pharmacology
– volume: 19
  start-page: 615
  issue: 5
  year: 1983
  end-page: 621
  article-title: Tamoxifen induces accumulation of MCF 7 human mammary carcinoma cells in the G0/G1 phase of the cell cycle
  publication-title: European Journal of Cancer & Clinical Oncology
– volume: 24
  start-page: 723
  issue: 6
  year: 2009
  end-page: 731
  article-title: Potential utility of radioprotective agents in the practice of nuclear medicine
  publication-title: Cancer Biotherapy and Radiopharmaceuticals
– volume: 7
  start-page: 3703
  issue: 9
  year: 2016
  end-page: 3715
  article-title: The protective effect of resveratrol against cytotoxicity induced by mycotoxin, zearalenone
  publication-title: Food & Function
– volume: 30
  start-page: 406
  issue: 5
  year: 2016
  end-page: 418
  article-title: Protective mechanisms of resveratrol against methotrexate‐induced renal damage may involve BCRP/ABCG2
  publication-title: Fundamental and Clinical Pharmacology
– volume: 2016
  year: 2016
  article-title: Resveratrol regulates mitochondrial biogenesis and fission/fusion to attenuate rotenone‐induced neurotoxicity
  publication-title: Oxidative Medicine and Cellular Longevity
– volume: 21
  start-page: 668
  issue: 4
  year: 2008
  end-page: 674
  article-title: A comparative study of grape seed extract and vitamin E effects on silica‐induced pulmonary fibrosis in rats
  publication-title: Pulmonary Pharmacology & Therapeutics
– volume: 50
  start-page: 3877
  issue: 11
  year: 2012
  end-page: 3885
  article-title: Combined treatment with capsaicin and resveratrol enhances neuroprotection against glutamate‐induced toxicity in mouse cerebral cortical neurons
  publication-title: Food and Chemical Toxicology
– volume: 74
  start-page: 158
  issue: 2
  year: 2008
  end-page: 169
  article-title: Aristolochic acid nephropathy: A worldwide problem
  publication-title: Kidney International
– volume: 36
  start-page: 105
  issue: 1
  year: 2007
  end-page: 114
  article-title: Black grape and garlic extracts protect against cyclosporine A nephrotoxicity
  publication-title: Immunological Investigations
– volume: 17
  start-page: 33
  issue: 1
  year: 2017
  article-title: Neuropsychiatric symptoms following metal‐on‐metal implant failure with cobalt and chromium toxicity
  publication-title: BMC Psychiatry
– volume: 29
  start-page: 2105
  issue: 11
  year: 2004
  end-page: 2112
  article-title: Resveratrol protects against neurotoxicity induced by kainic acid
  publication-title: Neurochemical Research
– volume: 28
  start-page: 886
  issue: 4
  year: 2007
  end-page: 891
  article-title: Resveratrol attenuates oxidative‐induced DNA damage in C6 Glioma cells
  publication-title: Neurotoxicology
– volume: 7
  start-page: 97
  issue: 1
  year: 2015
  end-page: 109
  article-title: Nephroprotective role of resveratrol and ursolic acid in aristolochic acid intoxicated zebrafish
  publication-title: Toxins
– volume: 13
  start-page: 2077
  issue: 10
  year: 1990
  end-page: 2087
  article-title: Quantitative determination of fumonisins B1 and B2 by high‐performance liquid chromatography with fluorescence detection
  publication-title: Journal of Liquid Chromatography
– volume: 57
  start-page: 296
  issue: 7
  year: 2013
  end-page: 306
  article-title: Inhibition of UVB‐induced skin phototoxicity by a grape seed extract as modulator of nitrosative stress, ERK/NF‐kB signaling pathway and apoptosis, in SKH‐1 mice
  publication-title: Food and Chemical Toxicology
– volume: 94
  start-page: 168
  issue: 2
  year: 2015
  end-page: 176
  article-title: Grape seed and skin extract protects against arsenic trioxide induced oxidative stress in rat heart
  publication-title: Canadian Journal of Physiology and Pharmacology
– volume: 303
  start-page: 65
  issue: 7
  year: 2016
  end-page: 78
  article-title: Resveratrol protects the ovary against chromium‐toxicity by enhancing endogenous antioxidant enzymes and inhibiting metabolic clearance of estradiol
  publication-title: Toxicology and Applied Pharmacology
– volume: 236
  start-page: 82
  issue: 2
  year: 2015
  end-page: 89
  article-title: Hepato‐protective effect of resveratrol against acetaminophen‐induced liver injury is associated with inhibition of CYP‐mediated bioactivation and regulation of SIRT1‐p53 signaling pathways
  publication-title: Toxicology Letters
– volume: 121
  start-page: 1048
  issue: 5
  year: 2001
  end-page: 1053
  article-title: Azathioprine treatment and male fertility in inflammatory bowel disease
  publication-title: Gastroenterology
– volume: 16
  start-page: 2
  issue: Special Issue
  year: 2017
  end-page: 23
  article-title: Black seed (Nigella Sativa) and its constituent thymoquinone as an antidote or a protective agent against natural or chemical toxicities
  publication-title: Iranian Journal of Pharmaceutical Research
– volume: 27
  start-page: 473
  issue: 4
  year: 2013
  end-page: 484
  article-title: Comparable molecular alterations in 4‐nitroquinoline 1‐oxide‐induced oral and esophageal cancer in mice and in human esophageal cancer, associated with poor prognosis of patients
  publication-title: In Vivo
– volume: 24
  start-page: 108
  issue: 2
  year: 2010
  end-page: 118
  article-title: Retinal protective effects of resveratrol via modulation of nitric oxide synthase on oxygen‐induced retinopathy
  publication-title: Korean Journal of Ophthalmology
– volume: 56
  start-page: 405
  year: 2013
  end-page: 411
  article-title: The genoprotective activity of resveratrol on permethrin‐induced genotoxic damage in cultured human lymphocytes
  publication-title: Brazilian Archives of Biology and Technology
– volume: 67
  start-page: 17
  issue: 3
  year: 1986
  end-page: 24
  article-title: Identification of the mutagens in cooked beef
  publication-title: Environmental Health Perspectives
– volume: 46
  start-page: 1529
  issue: 9
  year: 1993
  end-page: 1538
  article-title: An investigation of the formation of cytotoxic, genotoxic, protein‐reactive and stable metabolites from naphthalene by human liver microsomes
  publication-title: Biochemical Pharmacology
– volume: 12
  start-page: 4991
  issue: 8
  year: 2011
  end-page: 5010
  article-title: Resveratrol protects against 2‐bromopropane‐induced apoptosis and disruption of embryonic development in blastocysts
  publication-title: International Journal of Molecular Sciences
– volume: 20
  start-page: 538
  issue: 5
  year: 2017
  end-page: 551
  article-title: Berberis vulgaris and its constituent berberine as antidotes and protective agents against natural or chemical toxicities
  publication-title: Iranian Journal of Basic Medical Sciences
– volume: 6
  start-page: 21565
  issue: 6
  year: 2011
  article-title: Resveratrol acts not through anti‐aggregative pathways but mainly via its scavenging properties against Aβ and Aβ‐metal complexes toxicity
  publication-title: PLoS One
– volume: 267
  start-page: 2474
  issue: 4
  year: 1992
  end-page: 2479
  article-title: DNA strand scission and free radical production in menadione‐treated cells. Correlation with cytotoxicity and role of NADPH quinone acceptor oxidoreductase
  publication-title: Journal of Biological Chemistry
– volume: 82
  start-page: 308
  issue: 4
  year: 1984
  end-page: 310
  article-title: Depigmenting action of hydroquinone depends on disruption of fundamental cell processes
  publication-title: Journal of Investigative Dermatology
– volume: 63
  start-page: 1
  issue: 5
  year: 2016
  end-page: 12
  article-title: Chronic acrylamide exposure in male mice induces DNA damage to spermatozoa; Potential for amelioration by resveratrol
  publication-title: Reproductive Toxicology
– volume: 183
  start-page: 1815
  issue: 6
  year: 2013
  end-page: 1825
  article-title: Critical role of FoxO3a in alcohol‐induced autophagy and hepatotoxicity
  publication-title: The American Journal of Pathology
– volume: 74
  start-page: 577
  issue: 4
  year: 2003
  end-page: 588
  article-title: Ethanol‐induced oxidative stress precedes mitochondrially mediated apoptotic death of cultured fetal cortical neurons
  publication-title: Journal of Neuroscience Research
– volume: 31
  start-page: 819
  issue: 6
  year: 2017
  end-page: 837
  article-title: Effects of avocado (Persea americana) on metabolic syndrome: A comprehensive systematic review
  publication-title: Phytotherapy Research
– volume: 11
  start-page: 622
  issue: 2
  year: 2010
  end-page: 646
  article-title: Biological activities of polyphenols from grapes
  publication-title: International Journal of Molecular Sciences
– volume: 254
  start-page: 323
  issue: 3
  year: 2011
  end-page: 331
  article-title: Inhibition of arsenic‐induced rat liver injury by grape seed exact through suppression of NADPH oxidase and TGF‐beta/Smad activation
  publication-title: Toxicology and Applied Pharmacology
– volume: 262
  start-page: 122
  issue: 1‐2
  year: 2007
  end-page: 130
  article-title: Carbon monoxide intoxication: An updated review
  publication-title: Journal of the Neurological Sciences
– volume: 126
  start-page: 5
  issue: 1
  year: 2003
  end-page: 19
  article-title: Lead neurotoxicity in children: Basic mechanisms and clinical correlates
  publication-title: Brain
– volume: 4
  start-page: 893
  issue: 6
  year: 2002
  end-page: 898
  article-title: Protective effect of trans‐resveratrol on gentamicin‐induced nephrotoxicity
  publication-title: Antioxidants & Redox Signaling
– volume: 18
  start-page: 902
  issue: 9
  year: 2015
  end-page: 908
  article-title: Crocin reduced acrylamide‐induced neurotoxicity in Wistar rat through inhibition of oxidative stress
  publication-title: Iranian Journal of Basic Medical Sciences
– volume: 58
  start-page: 1811
  issue: 8
  year: 1998
  end-page: 1820
  article-title: Aminoglycosides: A practical review
  publication-title: American Family Physician
– volume: 30
  start-page: 1392
  issue: 9
  year: 2016
  end-page: 1403
  article-title: Review of the pharmacological effects of (grape) and its bioactive constituents: An update
  publication-title: Phytotherapy Research
– volume: 17
  start-page: 808
  issue: 6
  year: 2016
  article-title: The protective effect of grape‐seed proanthocyanidin extract on oxidative damage induced by zearalenone in Kunming mice liver
  publication-title: International Journal of Molecular Sciences
– volume: 77
  start-page: 2190
  issue: 10
  year: 2014
  end-page: 2195
  article-title: Protective effects of resveratrol on hepatotoxicity induced by isoniazid and rifampicin via SIRT1 modulation
  publication-title: Journal of Natural Products
– volume: 6
  start-page: 14575
  issue: 1
  year: 2011
  article-title: Differential neuroprotective activity of two different grape seed extracts
  publication-title: PLoS One
– volume: 34
  start-page: 244
  issue: 2
  year: 2010
  end-page: 262
  article-title: Grape seed proanthocyanidin extract chelates iron and attenuates the toxic effects of 6‐hydroxydopamine: Implications for Parkinson's disease
  publication-title: Journal of Food Biochemistry
– volume: 60
  start-page: 115
  issue: 2
  year: 2014
  end-page: 127
  article-title: Resveratrol reverses cadmium chloride‐induced testicular damage and subfertility by downregulating p53 and Bax and upregulating gonadotropins and Bcl‐2 gene expression
  publication-title: Journal of Reproduction and Development
– volume: 15
  start-page: 38
  issue: 1
  year: 2007
  end-page: 47
  article-title: Protective effect of grape seeds proanthocyanidins against naphthalene‐induced hepatotoxicity in rats
  publication-title: Saudi Pharmaceutical Journal
– volume: 270
  start-page: 28228
  issue: 47
  year: 1995
  end-page: 28233
  article-title: Free radicals generated during the glycation reaction of amino acids by methylglyoxal: A model study of protein‐cross‐linked free radicals
  publication-title: The Journal of Biological Chemistry
– volume: 59
  start-page: 853
  issue: 5
  year: 2015
  end-page: 864
  article-title: Resveratrol attenuates lipopolysaccharide‐induced acute kidney injury by suppressing inflammation driven by macrophages
  publication-title: Molecular Nutrition & Food Research
– volume: 23
  start-page: 255
  issue: 4
  year: 2003
  end-page: 261
  article-title: Resveratrol, a natural aryl hydrocarbon receptor antagonist, protects lung from DNA damage and apoptosis caused by benzo [a]pyrene
  publication-title: Journal of Applied Toxicology
– volume: 78
  start-page: 466
  issue: 3
  year: 2010
  end-page: 477
  article-title: Resveratrol protects dopamine neurons against lipopolysaccharide‐induced neurotoxicity through its anti‐inflammatory actions
  publication-title: Molecular Pharmacology
– volume: 11
  start-page: 27512
  issue: 2
  year: 2016
  article-title: Black grape seed extract modulates fluoxetine‐induced oxidative stress and cytotoxicity in the mouse testis
  publication-title: Jundishapur Journal of Natural Pharmaceutical Products
– volume: 155
  start-page: 83
  issue: 1
  year: 2000
  end-page: 90
  article-title: Chemopreventive effects of grape seed proanthocyanidin extract on Chang liver cells
  publication-title: Toxicology
– volume: 32
  start-page: 1109
  issue: 12
  year: 2009
  end-page: 1122
  article-title: Cisplatin overdose
  publication-title: Drug Safety
– volume: 9
  start-page: 2277
  issue: 12
  year: 2007
  end-page: 2293
  article-title: Endoplasmic reticulum stress and oxidative stress: A vicious cycle or a double‐edged sword?
  publication-title: Antioxidants & Redox Signaling
– volume: 28
  start-page: 200
  issue: 2
  year: 2008
  end-page: 213
  article-title: Protective effect of Kalpaamruthaa in combating the oxidative stress posed by aflatoxin B1‐induced hepatocellular carcinoma with special reference to flavonoid structure–activity relationship
  publication-title: Liver International
– volume: 169
  start-page: 633
  issue: 6
  year: 2008
  end-page: 638
  article-title: Resveratrol reduces radiation‐induced chromosome aberration frequencies in mouse bone marrow cells
  publication-title: Radiation Research
– volume: 10
  start-page: 1455
  issue: 3
  year: 2014
  end-page: 1460
  article-title: Amelioration of doxorubicininduced cardiotoxicity by resveratrol
  publication-title: Molecular Medicine Reports
– volume: 21
  start-page: 301
  issue: 3
  year: 2006
  end-page: 316
  article-title: Exploring cyclosporine A‐side effects and the protective role‐played by antioxidants: The morphological and immunohistochemical studies
  publication-title: Histology and Histopathology
– volume: 7
  start-page: 260
  issue: 1
  year: 2014
  end-page: 266
  article-title: Grape seed extract attenuates arsenic‐induced nephrotoxicity in rats
  publication-title: Experimental and Therapeutic Medicine
– volume: 8
  start-page: 59888
  issue: 3
  year: 2013
  article-title: Resveratrol inhibits β‐amyloid‐induced neuronal apoptosis through regulation of SIRT1‐ROCK1 signaling pathway
  publication-title: PLoS One
– volume: 160
  start-page: 1
  issue: 7
  year: 2016
  end-page: 10
  article-title: Hepatoprotective effect of grape seed oil against carbon tetrachloride induced oxidative stress in liver of gamma‐irradiated rat
  publication-title: Journal of Photochemistry and Photobiology B
– volume: 76
  start-page: 404
  issue: 3
  year: 2012
  end-page: 408
  article-title: Protective role of resveratrol against cisplatin induced ototoxicity in guinea pigs
  publication-title: International Journal of Pediatric Otorhinolaryngology
– volume: 32
  start-page: 876
  issue: 5
  year: 2009
  end-page: 881
  article-title: Attenuation of 2,3,7,8‐tetrachlorodibenzo‐p‐dioxin toxicity by resveratrol: A comparative study with different routes of administration
  publication-title: Biological and Pharmaceutical Bulletin
– volume: 28
  start-page: 321
  issue: 3
  year: 2007
  end-page: 325
  article-title: Effects of long‐term use of fluoxetine on fertility parameters in adult male rats
  publication-title: Neuro Endocrinology Letters
– volume: 63
  start-page: 293
  issue: 3
  year: 2012
  end-page: 301
  article-title: Resveratrol protects against acute chemotherapy toxicity induced by doxorubucin in rat erythrocyte and plasma
  publication-title: Journal of Physiology and Pharmacology
– volume: 2
  start-page: 677
  issue: 5
  year: 2015
  end-page: 684
  article-title: Co‐administration of fresh grape fruit juice (GFJ) and bergamottin prevented paracetamol induced hepatotoxicity after paracetamol overdose in rats
  publication-title: Toxicology Reports
– volume: 156
  start-page: 69
  issue: 1
  year: 2005
  end-page: 80
  article-title: Role of oxidative stress, mitochondrial membrane potential, and calcium homeostasis in nickel sulfate‐induced human lymphocyte death in vitro
  publication-title: Chemico‐Biological Interactions
– volume: 7
  start-page: 258
  issue: 3
  year: 2013
  end-page: 269
  article-title: Grape (Vitis vinifera) seed extract inhibits the cytotoxicity and oxidative stress in liver of rats treated with carbon tetrachloride
  publication-title: Global Journal of Pharmacology
– volume: 81
  start-page: 62
  issue: 7
  year: 2015
  end-page: 70
  article-title: Resveratrol prevents protein nitration and release of endonucleases from mitochondria during acetaminophen hepatotoxicity
  publication-title: Food and Chemical Toxicology
– volume: 39
  start-page: 73
  issue: 1
  year: 2012
  end-page: 86
  article-title: Anticancer drugs in surface waters
  publication-title: Environment International
– volume: 21
  start-page: 487
  issue: 6
  year: 2011
  end-page: 494
  article-title: Protective effects of grape seed procyanidin extract against nickel sulfate‐induced apoptosis and oxidative stress in rat testes
  publication-title: Toxicology Mechanisms and Methods
– volume: 22
  start-page: 511
  issue: 9
  year: 2006
  end-page: 519
  article-title: Historical origins and genetic diversity of wine grapes
  publication-title: Trends in Genetics
– volume: 69
  start-page: 322
  issue: 2
  year: 2017
  end-page: 330
  article-title: Manganese neurotoxicity and protective effects of resveratrol and quercetin in preclinical research
  publication-title: Pharmacological Reports
– volume: 5
  start-page: 6076
  issue: 25
  year: 2011
  end-page: 6084
  article-title: Grape seed extract mitigates garlic‐induced oxidative stress in rat spleen and plasma
  publication-title: Journal of Medicinal Plant Research
– volume: 26
  start-page: 42
  issue: 1
  year: 2006
  end-page: 46
  article-title: Cisplatin impairs antioxidant system and causes oxidation in rat kidney tissues: Possible protective roles of natural antioxidant foods
  publication-title: Journal of Applied Toxicology
– volume: 210
  start-page: 55
  issue: 1
  year: 2005
  end-page: 64
  article-title: Resveratrol, a polyphenolic phytoalexin protects against cyclosporine‐induced nephrotoxicity through nitric oxide dependent mechanism
  publication-title: Toxicology
– volume: 128
  start-page: 484
  issue: 4
  year: 2008
  end-page: 500
  article-title: Manganese exposure, essentiality & toxicity
  publication-title: Indian Journal of Medical Research
– volume: 31
  start-page: 344
  issue: 4
  year: 2013
  end-page: 351
  article-title: Antioxidant and antiapoptotic effects of proanthocyanidin and ginkgo biloba extract against doxorubicin‐induced cardiac injury in rats
  publication-title: Cell Biochemistry and Function
– volume: 51
  start-page: 339
  issue: 3
  year: 2013
  end-page: 344
  article-title: Cardioprotective effect of grape‐seed proanthocyanidins on doxorubicin‐induced cardiac toxicity in rats
  publication-title: Pharmaceutical Biology
– volume: 66
  start-page: 419
  issue: 3
  year: 2014
  end-page: 429
  article-title: Amelioration of cisplatin‐induced nephrotoxicity by grape seed extract and fish oil is mediated by lowering oxidative stress and DNA damage
  publication-title: Cytotechnology
– volume: 23
  start-page: 1197
  issue: 9
  year: 2009
  end-page: 1204
  article-title: Review of the pharmacological effects of Vitis vinifera (Grape) and its bioactive compounds
  publication-title: Phytotherapy Research
– volume: 9
  start-page: 49
  issue: 1
  year: 2011
  end-page: 53
  article-title: Neuroprotective effect of resveratrol against methamphetamine‐induced dopaminergic apoptotic cell death in a cell culture model of neurotoxicity
  publication-title: Current Neuropharmacology
– volume: 47
  start-page: 1329
  issue: 9
  year: 2012
  end-page: 1334
  article-title: Resveratrol inhibits reproductive toxicity induced by deoxynivalenol
  publication-title: Journal of Environmental Science and Health. Part A
– volume: 87
  start-page: 1025
  issue: 6
  year: 2013
  end-page: 1035
  article-title: Resveratrol protects against arsenic trioxide‐induced nephrotoxicity by facilitating arsenic metabolism and decreasing oxidative stress
  publication-title: Archives of Toxicology
– volume: 3
  start-page: 63
  year: 2016
  end-page: 77
  article-title: Hepatoprotective effect of grape seed proanthocyanidins on Cadmium‐induced hepatic injury in rats: Possible involvement of mitochondrial dysfunction, inflammation and apoptosis
  publication-title: Toxicology Reports
– volume: 90
  start-page: 64
  issue: 4
  year: 2016
  end-page: 75
  article-title: Mechanism of diethylhexylphthalate (DEHP) induced testicular damage and of grape seed extract‐induced protection in the rat
  publication-title: Food and Chemical Toxicology
– volume: 7
  start-page: 4787
  issue: 12
  year: 2016
  end-page: 4797
  article-title: Grape seed extracted ( ) alleviate hepatic toxicity induced by the anti‐oestrogen tamoxifen in female albino rats
  publication-title: International Journal of Pharmaceutical Sciences Review and Research
– volume: 101
  start-page: 320
  issue: 5
  year: 2007
  end-page: 327
  article-title: Effects of marjoram volatile oil and grape seed extract on ethanol toxicity in male rats
  publication-title: Basic & Clinical Pharmacology & Toxicology
– volume: 2014
  start-page: 698628
  issue: 6
  year: 2014
  article-title: Effect of resveratrol on hematological and biochemical alterations in rats exposed to fluoride
  publication-title: BioMed Research International
– volume: 36
  start-page: 217
  issue: 4
  year: 2003
  end-page: 228
  article-title: Fluoride and oxidative stress
  publication-title: Fluoride
– year: 1998
– volume: 7
  start-page: 99
  issue: 2
  year: 2014
  end-page: 106
  article-title: Cypermethrin‐induced reproductive toxicity in the rat is prevented by resveratrol
  publication-title: Journal of Human Reproductive Sciences
– volume: 27
  start-page: 1459
  issue: 9
  year: 2004
  end-page: 1461
  article-title: Grape seed extract prevents H2O2‐induced chromosomal damage in human lymphoblastoid cells
  publication-title: Biological and Pharmaceutical Bulletin
– volume: 28
  start-page: 1971
  issue: 6
  year: 2015
  end-page: 1978
  article-title: Efficacy of grape seed and skin extract against doxorubicin‐induced oxidative stress in rat liver
  publication-title: Pakistan Journal of Pharmaceutical Sciences
– volume: 80
  start-page: 1033
  issue: 11
  year: 2007
  end-page: 1039
  article-title: Resveratrol, a red wine polyphenol, attenuates ethanol‐induced oxidative stress in rat liver
  publication-title: Life Sciences
– volume: 5
  start-page: 224
  issue: 1
  year: 2016
  end-page: 234
  article-title: Grape seed proanthocyanidin extract protects against perfluorooctanoic acid‐induced hepatotoxicity by attenuating inflammatory response, oxidative stress and apoptosis in mice
  publication-title: Toxicological Research
– volume: 3
  start-page: 377
  issue: 5
  year: 2009
  end-page: 382
  article-title: Investigation on the protective effect of grape seed and Linseed oils against ciclophosphamide induced genotoxicity in mice
  publication-title: Global Veterinaria
– volume: 13
  start-page: 917
  issue: 4
  year: 2010
  end-page: 925
  article-title: Protective role of grape seed extract against doxorubicin‐induced cardiotoxicity and genotoxicity in albino mice
  publication-title: Journal of Medicinal Food
– volume: 13
  start-page: 303
  issue: 2
  year: 2010
  end-page: 310
  article-title: Resveratrol protects against methotrexate‐induced hepatic injury in rats
  publication-title: Journal of Pharmacy and Pharmaceutical Sciences
– volume: 33
  start-page: 576
  issue: 7
  year: 2013
  end-page: 585
  article-title: Toxic effects of cypermethrin on the male reproductive system: With emphasis on the androgen receptor
  publication-title: Journal of Applied Toxicology
– volume: 135
  start-page: 218
  issue: 1
  year: 2013
  end-page: 228
  article-title: Impact of manganese neurotoxicity on MMP‐9 production and superoxide dismutase activity in rat primary astrocytes. Effect of resveratrol and therapeutical implications for the treatment of CNS diseases
  publication-title: Toxicological Sciences
– volume: 16
  start-page: 120
  issue: 2
  year: 2008
  end-page: 128
  article-title: The effects of oral grape seed extract on cisplatin‐induced cytogenotoxicity in mice
  publication-title: Saudi Pharmaceutical Journal
– volume: 34
  start-page: 460
  issue: 4
  year: 2012
  end-page: 466
  article-title: Antiapoptotic and antioxidant effects of GSPE in preventing cyclosporine A‐induced cardiotoxicity
  publication-title: Renal Failure
– volume: 6
  start-page: 29102
  issue: 12
  year: 2011
  article-title: Resveratrol protects rats from Aβ‐induced neurotoxicity by the reduction of iNOS expression and lipid peroxidation
  publication-title: PLoS One
– volume: 135
  start-page: 466
  issue: 3
  year: 2015
  end-page: 478
  article-title: Resveratrol prevents cadmium activation of Erk1/2 and JNK pathways from neuronal cell death via protein phosphatases 2A and 5
  publication-title: Journal of Neurochemistry
– volume: 41
  start-page: 159
  issue: 1
  year: 2016
  end-page: 166
  article-title: Grape‐seed proanthocyanidins inhibit the lipopolysaccharide‐induced inflammatory mediator expression in RAW264.7 macrophages by suppressing MAPK and NF‐κb signal pathways
  publication-title: Environmental Toxicology and Pharmacology
– volume: 31
  start-page: 1199
  issue: 12
  year: 2012
  end-page: 1206
  article-title: Curcumin and resveratrol in combination modulates benzo (a)pyrene‐induced genotoxicity during lung carcinogenesis
  publication-title: Human and Experimental Toxicology
– volume: 19
  start-page: 92
  issue: 2
  year: 2008
  end-page: 98
  article-title: The effect of grape seed extract on radiation‐induced oxidative stress in the rat liver
  publication-title: The Turkish Journal of Gastroenterology
– volume: 2014
  start-page: 741018
  issue: 5
  year: 2014
  article-title: Side effects of radiographic contrast media: Pathogenesis, risk factors, and prevention
  publication-title: BioMed Research International
– volume: 32
  start-page: 662
  issue: 6
  year: 2013
  end-page: 671
  article-title: Resveratrol ameliorates methotrexate‐induced hepatotoxicity in rats via inhibition of lipid peroxidation
  publication-title: Human and Experimental Toxicology
– volume: 8
  start-page: 69452
  issue: 7
  year: 2013
  article-title: Resveratrol alleviates endotoxin‐induced myocardial toxicity via the Nrf2 transcription factor
  publication-title: PLoS One
– volume: 104
  start-page: 192
  issue: 3
  year: 2009
  end-page: 197
  article-title: Procyanidins produce significant attenuation of doxorubicin‐induced cardiotoxicity via suppression of oxidative stress
  publication-title: Basic & Clinical Pharmacology & Toxicology
– year: 2016
– volume: 52
  start-page: 1294
  issue: 8
  year: 2012
  end-page: 1306
  article-title: Resveratrol potentiates cytochrome P450 2d22‐mediated neuroprotection in maneb‐and paraquat‐induced Parkinsonism in the mouse
  publication-title: Free Radical Biology and Medicine
– volume: 141
  start-page: 997
  issue: 6
  year: 2004
  end-page: 1005
  article-title: Neuroprotective effects of resveratrol against beta‐amyloid‐induced neurotoxicity in rat hippocampal neurons: Involvement of protein kinase C
  publication-title: British Journal of Pharmacology
– volume: 565
  start-page: 190
  issue: 1‐3
  year: 2007
  end-page: 201
  article-title: Effect of silymarin on pyrogallol‐ and rifampicin‐induced hepatotoxicity in mouse
  publication-title: European Journal of Pharmacology
– volume: 14
  start-page: 861
  issue: 6
  year: 2015
  end-page: 876
  article-title: Biosynthetically engineered lipopolysaccharide as vaccine adjuvant
  publication-title: Expert Review of Vaccines
– volume: 26
  start-page: 33
  issue: 1
  year: 2013
  end-page: 42
  article-title: Effects of cadmium on the sub‐cellular localization of β‐catenin and β‐catenin‐regulated gene expression in NRK‐52E cells
  publication-title: Biometals
– volume: 42
  start-page: 913
  issue: 11‐12
  year: 2008
  end-page: 920
  article-title: Protective effect of resveratrol on acute endotoxemia‐induced nephrotoxicity in rat through nitric oxide independent mechanism
  publication-title: Free Radical Research
– volume: 23
  start-page: 31
  issue: 1
  year: 2015
  article-title: Saffron as an antidote or a protective agent against natural or chemical toxicities
  publication-title: DARU Journal of Pharmaceutical Sciences
– year: 2014
  article-title: Effect of Saffron extract on Acrylamide‐induced toxicity: In vitro and in vivo assessment
  publication-title: Chinese Journal of Integrative Medicine
– volume: 73
  start-page: 99
  issue: 2
  year: 2012
  end-page: 105
  article-title: Autophagy induced by resveratrol prevents human prion protein‐mediated neurotoxicity
  publication-title: Neuroscience Research
– volume: 10
  issue: 8
  year: 2015
  article-title: In vitro protective effect and antioxidant mechanism of resveratrol induced by dapsone hydroxylamine in human cells
  publication-title: PLoS One
– volume: 55
  start-page: 192
  issue: 5
  year: 2013
  end-page: 201
  article-title: Neuroprotective effects of resveratrol on embryonic dorsal root ganglion neurons with neurotoxicity induced by ethanol
  publication-title: Food and Chemical Toxicology
– volume: 17
  start-page: S21
  issue: 6
  year: 2003
  end-page: S28
  article-title: Immunopathogenesis of HIV‐related heart muscle disease: Current perspectives
  publication-title: AIDS
– volume: 71
  start-page: 514
  issue: 9
  year: 2016
  end-page: 523
  article-title: Resveratrol protects against triptolide‐induced cardiotoxicity through SIRT3 signaling pathway in vivo and in vitro
  publication-title: Die Pharmazie
– volume: 8
  start-page: 815
  issue: 7
  year: 2001
  end-page: 828
  article-title: Brain oxidative stress in animal models of accelerated aging and the age‐related neurodegenerative disorders, Alzheimer's disease and Huntington's Disease
  publication-title: Current Medicinal Chemistry
– volume: 211
  start-page: 246
  issue: 3
  year: 2012
  end-page: 256
  article-title: Zearalenone exposure modulates the expression of ABC transporters and nuclear receptors in pregnant rats and fetal liver
  publication-title: Toxicology Letters
– volume: 24
  start-page: 1710
  issue: 11
  year: 2010
  end-page: 1715
  article-title: Grape seed extract prevents azathioprine toxicity in rats
  publication-title: Phytotherapy Research
– volume: 32
  start-page: 106
  issue: 1
  year: 2016
  end-page: 117
  article-title: The effects of resveratrol against trifluralin toxicity in the urinary tract of rats
  publication-title: Toxicology and Industrial Health
– volume: 55
  start-page: 209
  issue: 2
  year: 2011
  end-page: 219
  article-title: Resveratrol (3,5,4′‐trihydroxystilbene) protects pregnant mother and fetus from the immunotoxic effects of 2,3,7,8‐tetrachlorodibenzo‐p‐dioxin
  publication-title: Molecular Nutrition & Food Research
– volume: 46
  start-page: 110
  issue: 5
  year: 2016
  end-page: 115
  article-title: Effects of resveratrol on carbon monoxide‐induced cardiotoxicity in rats
  publication-title: Environmental Toxicology and Pharmacology
– volume: 20
  start-page: 557
  issue: 5
  year: 2017
  end-page: 568
  article-title: A review of the effects of Berberis vulgaris and its major component, berberine, in metabolic syndrome
  publication-title: Iranian Journal of Basic Medical Sciences
– volume: 596
  start-page: 146
  issue: 1‐3
  year: 2008
  end-page: 152
  article-title: Resveratrol modulates pyrogallol‐induced changes in hepatic toxicity markers, xenobiotic metabolizing enzymes and oxidative stress
  publication-title: European Journal of Pharmacology
– volume: 22
  start-page: 403
  issue: 3
  year: 2016
  end-page: 408
  article-title: Grape seed proanthocyanidins extract prevents cisplatin‐induced cardiotoxicity in rats
  publication-title: Food Science and Technology Research
– volume: 31
  start-page: 769
  issue: 7
  year: 2016
  end-page: 784
  article-title: Resveratrol can prevent CCl₄‐induced liver injury by inhibiting Notch signaling pathway
  publication-title: Histology and Histopathology
– volume: 4
  start-page: 285
  issue: 4
  year: 2010
  end-page: 291
  article-title: Protective effect of grape seed extract on gentamicin‐induced acute kidney injury
  publication-title: Iranian Journal of Kidney Diseases
– volume: 15
  start-page: 6
  issue: 1
  year: 2015
  article-title: Chemosensitizing and nephroprotective effect of resveratrol in cisplatin–treated animals
  publication-title: Cancer Cell International
– volume: 22
  start-page: 88
  issue: sup1
  year: 2005
  end-page: 93
  article-title: Ochratoxin A: Potential epigenetic mechanisms of toxicity and carcinogenicity
  publication-title: Food Additives & Contaminants
– volume: 31
  start-page: 201
  issue: 1
  year: 2000
  end-page: 206
  article-title: Antituberculosis drug‐related liver dysfunction in chronic hepatitis B infection
  publication-title: Hepatology
– volume: 7
  start-page: 2
  issue: 1
  year: 2010
  end-page: 12
  article-title: Merging traditional Chinese medicine with modern drug discovery technologies to find novel drugs and functional foods
  publication-title: Current Drug Discovery Technologies
– volume: 81
  start-page: 647
  issue: 8
  year: 2007
  end-page: 656
  article-title: Effects of resveratrol on glycerol‐induced renal injury
  publication-title: Life Sciences
– volume: 100
  start-page: 115
  issue: Supplement C
  year: 2017
  end-page: 137
  article-title: Protective effects of green tea and its main constituents against natural and chemical toxins: A comprehensive review
  publication-title: Food and Chemical Toxicology
– volume: 16
  start-page: 1341
  issue: 6
  year: 2013
  end-page: 1350
  article-title: Role of convergent activation of glutamatergic and dopaminergic systems in the nucleus accumbens in the development of methamphetamine psychosis and dependence
  publication-title: International Journal of Neuropsychopharmacology
– volume: 13
  start-page: 702
  issue: 5
  year: 2011
  end-page: 709
  article-title: Effects of di‐n‐butyl phthalate on male rat reproduction following pubertal exposure
  publication-title: Asian Journal of Andrology
– volume: 1852
  start-page: 1298
  issue: 7
  year: 2015
  end-page: 1310
  article-title: Protective effects of resveratrol on the inhibition of hippocampal neurogenesis induced by ethanol during early postnatal life
  publication-title: Biochimica et Biophysica Acta
– volume: 342
  start-page: 81
  issue: 1
  year: 2012
  end-page: 90
  article-title: Resveratrol Inhibits paraquat‐induced oxidative stress and fibrogenic response by activating the nuclear factor erythroid 2‐related factor 2 pathway
  publication-title: Journal of Pharmacology and Experimental Therapeutics
– volume: 9
  start-page: 37
  issue: 1
  year: 2015
  end-page: 42
  article-title: Lipid‐lowering and hepatoprotective effects of Vitis vinifera dried seeds on paracetamol‐induced hepatotoxicity in rats
  publication-title: Nutrition Research and Practice
– volume: 9
  start-page: 3354
  issue: 9
  year: 2012
  end-page: 3364
  article-title: Resveratrol inhibited hydroquinone‐induced cytotoxicity in mouse primary hepatocytes
  publication-title: International Journal of Environmental Research and Public Health
– volume: 20
  start-page: 12250
  issue: 7
  year: 2015
  end-page: 12265
  article-title: Protective effect of procyanidin B2 against CCl4‐induced acute liver injury in mice
  publication-title: Molecules
– volume: 349
  start-page: 1731
  issue: 18
  year: 2003
  end-page: 1737
  article-title: The toxicology of mercury—Current exposures and clinical manifestations
  publication-title: Environmental Toxicology and Pharmacology
– volume: 8
  start-page: 163
  year: 2011
  article-title: Differential regional expression patterns of alpha‐synuclein, TNF‐alpha, and IL‐1beta; and variable status of dopaminergic neurotoxicity in mouse brain after Paraquat treatment
  publication-title: Journal of Neuroinflammation
– volume: 60
  start-page: 237
  issue: 4
  year: 2003
  end-page: 243
  article-title: Chronic obstructive pulmonary disease due to occupational exposure to silica dust: A review of epidemiological and pathological evidence
  publication-title: Occupational and Environmental Medicine
– volume: 36
  start-page: 861
  issue: 05
  year: 2008
  end-page: 872
  article-title: Role of grape seed extract on methotrexate induced oxidative stress in rat liver
  publication-title: The American Journal of Chinese Medicine
– volume: 52
  start-page: 287
  issue: 2
  year: 2013
  end-page: 291
  article-title: Resveratrol mitigates genotoxicity induced by iodine‐131 in primary human lymphocytes
  publication-title: Radiation and Environmental Biophysics
– volume: 49
  start-page: 28
  issue: 4
  year: 2015
  end-page: 35
  article-title: Ammonia‐induced oxidative damage in neurons is prevented by resveratrol and lipoic acid with participation of heme oxygenase 1
  publication-title: Neurotoxicology
– volume: 4
  start-page: 151
  issue: 1
  year: 2011
  end-page: 155
  article-title: Resveratrol attenuates azidothymidine‐induced cardiotoxicity by decreasing mitochondrial reactive oxygen species generation in human cardiomyocytes
  publication-title: Molecular Medicine Reports
– volume: 17
  start-page: 485
  issue: 5‐6
  year: 2006
  end-page: 492
  article-title: Effect of resveratrol on 3‐nitropropionic acid‐induced biochemical and behavioural changes: Possible neuroprotective mechanisms
  publication-title: Behavioural Pharmacology
– volume: 27
  start-page: 133
  issue: 1
  year: 2011
  end-page: 140
  article-title: Effects of grape seed extract and origanum onites essential oil on cisplatin‐induced hepatotoxicity in rats
  publication-title: International Journal of Hematology and Oncology
– volume: 24
  start-page: 675
  issue: 6
  year: 2009
  end-page: 680
  article-title: Resveratrol protects against Cisplatin‐induced cardiotoxicity by alleviating oxidative damage
  publication-title: Cancer Biotherapy and Radiopharmaceuticals
– volume: 5
  start-page: 6316
  issue: 27
  year: 2011
  end-page: 6327
  article-title: Protective effect of milk thistle and grape seed extracts on fumonisin B1 induced Hepato‐and nephro‐toxicity in rats
  publication-title: Journal of Medicinal Plant Research
– volume: 46
  start-page: 1627
  issue: 5
  year: 2008
  end-page: 1634
  article-title: Effect of grape (Vitis vinifera L.) leaf extract on alcohol induced oxidative stress in rats
  publication-title: Food and Chemical Toxicology
– volume: 41
  start-page: 252
  issue: 4
  year: 2015
  end-page: 260
  article-title: Neuroprotection of resveratrol against neurotoxicity induced by methamphetamine in mouse mesencephalic dopaminergic neurons
  publication-title: Biofactors
– volume: 721
  start-page: 171
  issue: 2
  year: 2011
  end-page: 177
  article-title: Protection of resveratrol and its analogues against ethanol‐induced oxidative DNA damage in human peripheral lymphocytes
  publication-title: Mutation Research, Genetic Toxicology and Environmental Mutagenesis
– volume: 35
  start-page: 513
  issue: 4
  year: 2015
  end-page: 522
  article-title: Resveratrol protects PC12 cells from high glucose‐induced neurotoxicity via PI3K/Akt/FoxO3a pathway
  publication-title: Cellular and Molecular Neurobiology
– volume: 30
  start-page: 540
  issue: 4
  year: 2016
  end-page: 556
  article-title: Grapes (Vitis vinifera) as a potential candidate for the therapy of the metabolic syndrome
  publication-title: Phytotherapy Research
– volume: 54
  start-page: 291
  issue: 4
  year: 2015
  end-page: 300
  article-title: Grape seed extract and resveratrol prevent 4‐nitroquinoline 1‐oxide induced oral tumorigenesis in mice by modulating AMPK activation and associated biological responses
  publication-title: Molecular Carcinogenesis
– volume: 24
  start-page: 276
  issue: 4
  year: 2014
  end-page: 283
  article-title: Anti‐tumor activity of grape juice concentrate in the rat tongue two‐stage initiation–promotion protocol induced by 4‐nitroquinoline 1‐oxide
  publication-title: Toxicology Mechanisms and Methods
– volume: 17
  start-page: 372
  issue: 4
  year: 2012
  end-page: 379
  article-title: Anti‐apoptotic and anti‐oxidant effects of grape seed proanthocyanidin extract in preventing cyclosporine A‐induced nephropathy
  publication-title: Nephrology
– volume: 21
  start-page: 223
  issue: 3
  year: 2011
  end-page: 227
  article-title: Dacarbazine‐based chemotherapy as first‐line treatment in noncutaneous metastatic melanoma: Multicenter, retrospective analysis in Asia
  publication-title: Melanoma Research
– volume: 28
  start-page: 474
  issue: 5
  year: 2012
  end-page: 480
  article-title: The genoprotective activity of resveratrol on aflatoxin B1‐induced DNA damage in human lymphocytes in vitro
  publication-title: Toxicology and Industrial Health
– volume: 34
  start-page: 1100
  issue: 8
  year: 2003
  end-page: 1110
  article-title: Protective effect of resveratrol on beta‐amyloid‐induced oxidative PC12 cell death
  publication-title: Free Radical Biology and Medicine
– volume: 51
  start-page: 87
  issue: 1
  year: 2013
  end-page: 92
  article-title: Resveratrol attenuates hepatotoxicity of rats exposed to arsenic trioxide
  publication-title: Food and Chemical Toxicology
– volume: 7
  start-page: 12
  issue: 1
  year: 2012
  article-title: Skin toxicity from external beam radiation therapy in breast cancer patients: Protective effects of Resveratrol, Lycopene, Vitamin C and anthocianin (Ixor®)
  publication-title: Radiation Oncology
– volume: 47
  start-page: 1499
  issue: 7
  year: 2009
  end-page: 1506
  article-title: Cisplatin induced damage in kidney genomic DNA and nephrotoxicity in male rats: The protective effect of grape seed proanthocyanidin extract
  publication-title: Food and Chemical Toxicology
– volume: 28
  start-page: 272
  issue: 4
  year: 2015
  end-page: 280
  article-title: Grape seed proanthocyanidin extract alleviates arsenic‐induced oxidative reproductive toxicity in male mice
  publication-title: Biomedical and Environmental Sciences
– volume: 6
  start-page: 352
  issue: 12
  year: 2010
  end-page: 361
  article-title: Grape seed extract alleviate reproductive toxicity caused by aluminium chloride in male rats
  publication-title: Journal of American Science
– volume: 32
  start-page: 227
  issue: 2
  year: 2012
  end-page: 235
  article-title: Neuroprotective effect of crocin on acrylamide‐induced cytotoxicity in PC12 cells
  publication-title: Cellular and Molecular Neurobiology
– volume: 17
  start-page: 663
  issue: 6
  year: 2014
  end-page: 669
  article-title: Antioxidant properties of proanthocyanidins attenuate carbon tetrachloride (CCl4)–induced steatosis and liver injury in rats via CYP2E1 regulation
  publication-title: Journal of Medicinal Food
– volume: 28
  start-page: 350
  issue: 3
  year: 2009
  end-page: 356
  article-title: Resveratrol ameliorates carbon tetrachloride‐induced acute liver injury in mice
  publication-title: Environmental Toxicology and Pharmacology
– volume: 20
  start-page: 642
  issue: 6
  year: 2007
  end-page: 649
  article-title: Resveratrol alleviates bleomycin‐induced lung injury in rats
  publication-title: Pulmonary Pharmacology & Therapeutics
– volume: 59
  start-page: 72
  issue: 2
  year: 2016
  end-page: 77
  article-title: Preparation, characterization and evaluation of 186Re‐idarubicin: A novel agent for diagnosis and treatment of hepatocellular carcinoma
  publication-title: Journal of Labelled Compounds and Radiopharmaceuticals
– volume: 273
  start-page: 1
  issue: 9
  year: 2017
  end-page: 9
  article-title: Grape seed extract ameliorates bleomycin‐induced mouse pulmonary fibrosis
  publication-title: Toxicology Letters
– volume: 14
  start-page: 385
  issue: 5
  year: 2000
  end-page: 401
  article-title: Rat two‐generation reproduction and dominant lethal study of acrylamide in drinking water
  publication-title: Reproductive Toxicology
– volume: 23
  start-page: 415
  issue: 6
  year: 2003
  end-page: 421
  article-title: Carvedilol, an antihypertensive drug with antioxidant properties, protects against glycerol‐induced acute renal failure
  publication-title: American Journal of Nephrology
– volume: 4
  start-page: 23
  issue: 1
  year: 2004
  end-page: 35
  article-title: Prevention of non‐melanoma skin cancer by targeting ultraviolet‐B‐light signalling
  publication-title: Nature Reviews Cancer
– volume: 116
  start-page: 2947
  issue: 12
  year: 2015
  end-page: 2955
  article-title: The phytoalexin resveratrol ameliorates ochratoxin A toxicity in human embryonic kidney (HEK293) cells
  publication-title: Journal of Cellular Biochemistry
– volume: 2014
  start-page: 617202
  year: 2014
  article-title: Resveratrol, a natural antioxidant, has a protective effect on liver injury induced by inorganic arsenic exposure
  publication-title: BioMed Research International
– volume: 8
  start-page: 656
  issue: 10
  year: 2016
  article-title: Proanthocyanidins attenuation of chronic lead‐induced liver oxidative damage in Kunming mice via the Nrf2/ARE pathway
  publication-title: Nutrients
– volume: 28
  start-page: 431
  issue: 8
  year: 2013
  end-page: 441
  article-title: Resveratrol protects against methylglyoxal‐induced apoptosis and disruption of embryonic development in mouse blastocysts
  publication-title: Environmental Toxicology
– volume: 40
  start-page: 1600
  issue: 8
  year: 2015
  end-page: 1608
  article-title: Resveratrol protects hippocampal astrocytes against LPS‐induced neurotoxicity through HO‐1, p38 and ERK pathways
  publication-title: Neurochemical Research
– volume: 22
  start-page: 387
  issue: 5
  year: 1996
  end-page: 391
  article-title: Hematopoietic and reproductive hazards of Korean electronic workers exposed to solvents containing 2‐bromopropane
  publication-title: Scandinavian Journal of Work, Environment and Health
– volume: 147
  start-page: 156
  issue: 1
  year: 2012
  end-page: 164
  article-title: Effect of grape seed proanthocyanidin extracts on methylmercury‐induced neurotoxicity in rats
  publication-title: Biological Trace Element Research
– volume: 37
  start-page: 369
  issue: 4
  year: 2016
  end-page: 378
  article-title: Protective effect of resveratrol against aluminum chloride induced nephrotoxicity in rats
  publication-title: Saudi Medical Journal
– volume: 2014
  start-page: 398285
  year: 2014
  article-title: Flutamide‐induced cytotoxicity and oxidative stress in an in vitro rat hepatocyte system
  publication-title: Oxidative Medicine and Cellular Longevity
– volume: 78
  start-page: 290
  issue: 5
  year: 2004
  end-page: 300
  article-title: Effect of 2,3,7,8‐tetrachlorodibenzo‐p‐dioxin (TCDD) on maternal immune response during pregnancy
  publication-title: Archives of Toxicology
– volume: 1094
  start-page: 103
  issue: 1
  year: 1991
  end-page: 112
  article-title: Effects of steroidal and non‐steroidal antiandrogens on the androgen binding properties of the rat ventral prostate androgen receptor
  publication-title: Biochimica et Biophysica Acta
– volume: 55
  start-page: 467
  issue: 2
  year: 2004
  end-page: 476
  article-title: The protective effects of resveratrol against changes in blood platelet thiols induced by platinum compounds
  publication-title: Journal of Physiology and Pharmacology
– volume: 18
  start-page: 159
  issue: 1
  year: 1982
  end-page: 163
  article-title: Compensatory mechanisms in the nigrostriatal dopaminergic system in Parkinson's disease: Studies in an animal model
  publication-title: Israel Journal of Medical Sciences
– volume: 8
  start-page: 6233
  issue: 4
  year: 2017
  end-page: 6245
  article-title: Protective effects of resveratrol against mancozeb induced apoptosis damage in mouse oocytes
  publication-title: Oncotarget
– year: 2017
– volume: 131
  start-page: 711
  issue: 4
  year: 2000
  end-page: 720
  article-title: Neuroprotective abilities of resveratrol and other red wine constituents against nitric oxide‐related toxicity in cultured hippocampal neurons
  publication-title: British Journal of Pharmacology
– volume: 99
  start-page: 230
  issue: 3
  year: 2006
  end-page: 236
  article-title: Grape seed extract prevents gentamicin‐induced nephrotoxicity and genotoxicity in bone marrow cells of mice
  publication-title: Basic & Clinical Pharmacology & Toxicology
– volume: 40
  start-page: 66
  issue: 1
  year: 2015
  end-page: 73
  article-title: The effects of grape seed extract against toxicity of benzene on liver and kidney tissues of albino mice: Biochemical evaluation
  publication-title: Turkish Journal of Biochemistry
– volume: 30
  start-page: 2027
  issue: 12
  year: 2016
  end-page: 2035
  article-title: Folic acid and grape seed extract prevent azathioprine‐induced fetal malformations and renal toxicity in rats
  publication-title: Phytotherapy Research
– volume: 280
  start-page: 314
  issue: 2
  year: 2014
  end-page: 322
  article-title: Resveratrol attenuates methylglyoxal‐induced mitochondrial dysfunction and apoptosis by Sestrin2 induction
  publication-title: Toxicology and Applied Pharmacology
– ident: e_1_2_7_126_1
  doi: 10.1016/j.lfs.2006.11.044
– ident: e_1_2_7_18_1
  doi: 10.1038/sj.bjp.0703626
– ident: e_1_2_7_176_1
  doi: 10.1021/np5003143
– volume: 128
  start-page: 484
  issue: 4
  year: 2008
  ident: e_1_2_7_206_1
  article-title: Manganese exposure, essentiality & toxicity
  publication-title: Indian Journal of Medical Research
– ident: e_1_2_7_186_1
  doi: 10.1021/jf800898p
– ident: e_1_2_7_279_1
  doi: 10.1016/j.fct.2012.09.023
– ident: e_1_2_7_221_1
  doi: 10.1159/000074453
– ident: e_1_2_7_67_1
  doi: 10.1080/08820130600745927
– volume: 9
  start-page: 145
  issue: 2
  year: 2013
  ident: e_1_2_7_179_1
  article-title: Molecular mechanisms of protective effect of resveratrol against cisplatinium induced ototoxicity
  publication-title: The Journal of International Advanced Otology
– ident: e_1_2_7_15_1
  doi: 10.1016/j.toxrep.2015.05.004
– ident: e_1_2_7_65_1
  doi: 10.1016/j.fct.2015.04.014
– ident: e_1_2_7_166_1
  doi: 10.1017/S1461145712001356
– volume: 71
  start-page: 514
  issue: 9
  year: 2016
  ident: e_1_2_7_265_1
  article-title: Resveratrol protects against triptolide‐induced cardiotoxicity through SIRT3 signaling pathway in vivo and in vitro
  publication-title: Die Pharmazie
– ident: e_1_2_7_184_1
  doi: 10.1155/2016/6705621
– ident: e_1_2_7_258_1
  doi: 10.3390/ijms11020622
– ident: e_1_2_7_145_1
  doi: 10.1111/jnc.13233
– ident: e_1_2_7_281_1
  doi: 10.1155/2014/617202
– ident: e_1_2_7_34_1
  doi: 10.4999/uhod.10060
– ident: e_1_2_7_8_1
  doi: 10.3892/mmr.2016.4928
– ident: e_1_2_7_27_1
  doi: 10.1038/nrc1253
– ident: e_1_2_7_205_1
  doi: 10.1039/C6FO00191B
– ident: e_1_2_7_254_1
  doi: 10.1007/978-1-4612-2862-2_1
– volume: 349
  start-page: 1731
  issue: 18
  year: 2003
  ident: e_1_2_7_48_1
  article-title: The toxicology of mercury—Current exposures and clinical manifestations
  publication-title: Environmental Toxicology and Pharmacology
– ident: e_1_2_7_211_1
  doi: 10.1016/j.pupt.2006.07.003
– volume: 67
  start-page: 17
  issue: 3
  year: 1986
  ident: e_1_2_7_81_1
  article-title: Identification of the mutagens in cooked beef
  publication-title: Environmental Health Perspectives
  doi: 10.1289/ehp.866717
– ident: e_1_2_7_271_1
  doi: 10.1007/s00204-013-1026-4
– ident: e_1_2_7_151_1
  doi: 10.3390/nu8100656
– ident: e_1_2_7_226_1
  doi: 10.1016/0167-4889(91)90031-R
– volume: 7
  start-page: 81
  issue: 3
  year: 2013
  ident: e_1_2_7_98_1
  article-title: Protective effect of black grapes seed hydroalcholic extract against fluoxetine‐induced embryo toxicity in male mice
  publication-title: International Journal of Fertility & Sterility
– ident: e_1_2_7_122_1
  doi: 10.1016/S0300-483X(00)00280-8
– ident: e_1_2_7_240_1
  doi: 10.1590/S1516-89132013000300008
– ident: e_1_2_7_30_1
  doi: 10.2174/0929867013373048
– ident: e_1_2_7_84_1
  doi: 10.1016/S0024-3205(03)00179-6
– ident: e_1_2_7_239_1
  doi: 10.18433/J30K5Q
– ident: e_1_2_7_40_1
  doi: 10.1016/j.tox.2005.01.011
– volume: 19
  start-page: 92
  issue: 2
  year: 2008
  ident: e_1_2_7_35_1
  article-title: The effect of grape seed extract on radiation‐induced oxidative stress in the rat liver
  publication-title: The Turkish Journal of Gastroenterology
– ident: e_1_2_7_89_1
  doi: 10.1016/j.pharep.2016.11.011
– ident: e_1_2_7_155_1
  doi: 10.1177/0960327112440113
– ident: e_1_2_7_2_1
  doi: 10.1016/j.fct.2016.02.003
– volume: 15
  start-page: 38
  issue: 1
  year: 2007
  ident: e_1_2_7_4_1
  article-title: Protective effect of grape seeds proanthocyanidins against naphthalene‐induced hepatotoxicity in rats
  publication-title: Saudi Pharmaceutical Journal
– ident: e_1_2_7_128_1
  doi: 10.3341/kjo.2010.24.2.108
– ident: e_1_2_7_152_1
  doi: 10.3390/ijms17060808
– ident: e_1_2_7_209_1
  doi: 10.1080/10715760802555577
– ident: e_1_2_7_224_1
  doi: 10.1111/jpn.12260
– ident: e_1_2_7_269_1
  doi: 10.1074/jbc.270.47.28228
– ident: e_1_2_7_94_1
  doi: 10.2174/157016310791162767
– ident: e_1_2_7_41_1
  doi: 10.1371/journal.pone.0060654
– ident: e_1_2_7_45_1
  doi: 10.1002/mnfr.201400819
– ident: e_1_2_7_75_1
  doi: 10.1262/jrd.2013-097
– ident: e_1_2_7_20_1
  doi: 10.1007/s11064-015-1636-8
– ident: e_1_2_7_22_1
  doi: 10.1016/j.cbi.2008.11.015
– ident: e_1_2_7_246_1
  doi: 10.1016/j.ejphar.2007.03.004
– ident: e_1_2_7_121_1
  doi: 10.1016/j.neures.2012.03.005
– volume: 2007
  start-page: 87
  issue: 02
  year: 2007
  ident: e_1_2_7_123_1
  article-title: Protective effects of hydroalcoholic extract of red grape seed (VITIS VENIFERA) in nephrotoxicity induced by amikacin in mice
  publication-title: Jundishapur Journal of Natural Pharmaceutical Products
– ident: e_1_2_7_127_1
  doi: 10.1016/j.reprotox.2016.05.004
– ident: e_1_2_7_237_1
  doi: 10.1007/s004050100406
– volume: 4
  start-page: 151
  issue: 1
  year: 2011
  ident: e_1_2_7_87_1
  article-title: Resveratrol attenuates azidothymidine‐induced cardiotoxicity by decreasing mitochondrial reactive oxygen species generation in human cardiomyocytes
  publication-title: Molecular Medicine Reports
– ident: e_1_2_7_262_1
  doi: 10.1016/j.mrgentox.2011.01.012
– ident: e_1_2_7_256_1
  doi: 10.1002/hep.510310129
– ident: e_1_2_7_171_1
  doi: 10.1002/ptr.2761
– volume: 267
  start-page: 2474
  issue: 4
  year: 1992
  ident: e_1_2_7_177_1
  article-title: DNA strand scission and free radical production in menadione‐treated cells. Correlation with cytotoxicity and role of NADPH quinone acceptor oxidoreductase
  publication-title: Journal of Biological Chemistry
  doi: 10.1016/S0021-9258(18)45903-0
– ident: e_1_2_7_116_1
  doi: 10.1016/j.jnutbio.2012.04.005
– ident: e_1_2_7_191_1
  doi: 10.1016/j.tiv.2013.12.021
– ident: e_1_2_7_243_1
  doi: 10.1111/j.1440-1797.2012.01565.x
– ident: e_1_2_7_282_1
  doi: 10.1111/1750-3841.12815
– ident: e_1_2_7_159_1
  doi: 10.1172/JCI59755
– ident: e_1_2_7_268_1
  doi: 10.1097/CMR.0b013e3283457743
– ident: e_1_2_7_70_1
  doi: 10.5897/JMPR11.927
– ident: e_1_2_7_250_1
  doi: 10.3390/ijerph9093354
– volume: 34
  start-page: 973
  issue: 5
  year: 2015
  ident: e_1_2_7_267_1
  article-title: The comparison of resveratrol and N‐acetylcysteine on the oxidative kidney damage caused by high dose paracetamol
  publication-title: Latin American Journal of Pharmacy
– ident: e_1_2_7_73_1
  doi: 10.1002/ptr.3200
– ident: e_1_2_7_142_1
  doi: 10.3329/bjp.v10i2.22588
– volume: 31
  start-page: 769
  issue: 7
  year: 2016
  ident: e_1_2_7_233_1
  article-title: Resveratrol can prevent CCl₄‐induced liver injury by inhibiting Notch signaling pathway
  publication-title: Histology and Histopathology
– ident: e_1_2_7_60_1
  doi: 10.1053/gast.2001.28692
– ident: e_1_2_7_202_1
  doi: 10.1016/j.fct.2009.03.043
– volume: 20
  start-page: 557
  issue: 5
  year: 2017
  ident: e_1_2_7_231_1
  article-title: A review of the effects of Berberis vulgaris and its major component, berberine, in metabolic syndrome
  publication-title: Iranian Journal of Basic Medical Sciences
– ident: e_1_2_7_120_1
  doi: 10.1016/S0891-5849(03)00062-5
– ident: e_1_2_7_137_1
  doi: 10.1016/j.fct.2012.08.040
– ident: e_1_2_7_82_1
  doi: 10.1371/journal.pone.0059888
– ident: e_1_2_7_97_1
  doi: 10.17795/jjnpp-27512
– ident: e_1_2_7_156_1
  doi: 10.1089/ars.2007.1782
– ident: e_1_2_7_190_1
  doi: 10.1371/journal.pone.0064372
– ident: e_1_2_7_95_1
  doi: 10.1186/s12888-016-1174-1
– ident: e_1_2_7_194_1
  doi: 10.1002/jnr.10767
– ident: e_1_2_7_58_1
  doi: 10.1055/s-0035-1569452
– ident: e_1_2_7_147_1
  doi: 10.1007/s10571-014-0147-5
– ident: e_1_2_7_36_1
  doi: 10.1142/S0192415X08006302
– volume: 7
  start-page: 4787
  issue: 12
  year: 2016
  ident: e_1_2_7_3_1
  article-title: Grape seed extracted (vitis vinifera) alleviate hepatic toxicity induced by the anti‐oestrogen tamoxifen in female albino rats
  publication-title: International Journal of Pharmaceutical Sciences Review and Research
– ident: e_1_2_7_33_1
  doi: 10.5505/tjb.2015.22448
– ident: e_1_2_7_51_1
  doi: 10.2165/00003495-200060040-00005
– ident: e_1_2_7_111_1
  doi: 10.1089/cbr.2009.0635
– ident: e_1_2_7_217_1
  doi: 10.1523/JNEUROSCI.23-34-10756.2003
– volume: 20
  start-page: 538
  issue: 5
  year: 2017
  ident: e_1_2_7_167_1
  article-title: Berberis vulgaris and its constituent berberine as antidotes and protective agents against natural or chemical toxicities
  publication-title: Iranian Journal of Basic Medical Sciences
– volume: 7
  start-page: 258
  issue: 3
  year: 2013
  ident: e_1_2_7_192_1
  article-title: Grape (Vitis vinifera) seed extract inhibits the cytotoxicity and oxidative stress in liver of rats treated with carbon tetrachloride
  publication-title: Global Journal of Pharmacology
– ident: e_1_2_7_61_1
  doi: 10.1177/0748233713498437
– ident: e_1_2_7_253_1
  doi: 10.1016/j.toxlet.2015.05.001
– volume: 2012
  start-page: 973134
  issue: 6
  year: 2012
  ident: e_1_2_7_90_1
  article-title: Specific conditions for resveratrol neuroprotection against ethanol‐induced toxicity
  publication-title: Journal of Toxicology
– volume: 58
  start-page: 1811
  issue: 8
  year: 1998
  ident: e_1_2_7_91_1
  article-title: Aminoglycosides: A practical review
  publication-title: American Family Physician
– volume: 4
  start-page: 285
  issue: 4
  year: 2010
  ident: e_1_2_7_203_1
  article-title: Protective effect of grape seed extract on gentamicin‐induced acute kidney injury
  publication-title: Iranian Journal of Kidney Diseases
– ident: e_1_2_7_42_1
  doi: 10.1016/j.jnutbio.2009.02.004
– ident: e_1_2_7_183_1
  doi: 10.1016/j.fct.2008.01.003
– ident: e_1_2_7_134_1
  doi: 10.1093/toxsci/kft146
– volume: 21
  start-page: 301
  issue: 3
  year: 2006
  ident: e_1_2_7_200_1
  article-title: Exploring cyclosporine A‐side effects and the protective role‐played by antioxidants: The morphological and immunohistochemical studies
  publication-title: Histology and Histopathology
– ident: e_1_2_7_247_1
  doi: 10.1016/j.ejphar.2008.08.019
– ident: e_1_2_7_169_1
  doi: 10.1089/152308602762197434
– ident: e_1_2_7_28_1
  doi: 10.1039/c4tx00007b
– ident: e_1_2_7_220_1
  doi: 10.1248/bpb.30.79
– ident: e_1_2_7_62_1
  doi: 10.1007/s11064-016-1950-9
– ident: e_1_2_7_85_1
  doi: 10.1186/1748-717X-7-12
– ident: e_1_2_7_23_1
  doi: 10.1016/S0028-3908(98)00139-7
– ident: e_1_2_7_273_1
  doi: 10.1016/j.ijporl.2011.12.021
– ident: e_1_2_7_21_1
  doi: 10.1016/j.envint.2011.10.002
– volume: 28
  start-page: 1971
  issue: 6
  year: 2015
  ident: e_1_2_7_168_1
  article-title: Efficacy of grape seed and skin extract against doxorubicin‐induced oxidative stress in rat liver
  publication-title: Pakistan Journal of Pharmaceutical Sciences
– volume: 2014
  start-page: 741018
  issue: 5
  year: 2014
  ident: e_1_2_7_11_1
  article-title: Side effects of radiographic contrast media: Pathogenesis, risk factors, and prevention
  publication-title: BioMed Research International
– ident: e_1_2_7_245_1
  doi: 10.1111/j.1478-3231.2007.01615.x
– ident: e_1_2_7_131_1
  doi: 10.1080/10934529.2012.672144
– ident: e_1_2_7_148_1
  doi: 10.1016/j.toxlet.2017.03.012
– volume: 6
  start-page: 352
  issue: 12
  year: 2010
  ident: e_1_2_7_99_1
  article-title: Grape seed extract alleviate reproductive toxicity caused by aluminium chloride in male rats
  publication-title: Journal of American Science
– ident: e_1_2_7_242_1
  doi: 10.1016/S0890-6238(00)00097-6
– ident: e_1_2_7_182_1
  doi: 10.1016/j.taap.2011.04.022
– ident: e_1_2_7_278_1
  doi: 10.4162/nrp.2014.8.2.220
– volume: 27
  start-page: 473
  issue: 4
  year: 2013
  ident: e_1_2_7_266_1
  article-title: Comparable molecular alterations in 4‐nitroquinoline 1‐oxide‐induced oral and esophageal cancer in mice and in human esophageal cancer, associated with poor prognosis of patients
  publication-title: In Vivo
– ident: e_1_2_7_39_1
  doi: 10.3390/ijms12084991
– ident: e_1_2_7_86_1
  doi: 10.1016/j.freeradbiomed.2010.06.002
– ident: e_1_2_7_230_1
  doi: 10.1016/0277-5379(83)90177-3
– ident: e_1_2_7_135_1
  doi: 10.1093/toxsci/kfm128
– ident: e_1_2_7_204_1
  doi: 10.4103/0253-7613.125167
– ident: e_1_2_7_109_1
  doi: 10.1016/j.cbi.2012.05.004
– ident: e_1_2_7_164_1
  doi: 10.1124/pr.56.2.6
– ident: e_1_2_7_113_1
  doi: 10.1002/jat.1769
– volume: 18
  start-page: 902
  issue: 9
  year: 2015
  ident: e_1_2_7_160_1
  article-title: Crocin reduced acrylamide‐induced neurotoxicity in Wistar rat through inhibition of oxidative stress
  publication-title: Iranian Journal of Basic Medical Sciences
– ident: e_1_2_7_71_1
  doi: 10.1002/ptr.5709
– ident: e_1_2_7_260_1
  doi: 10.1089/jmf.2009.0162
– ident: e_1_2_7_6_1
  doi: 10.1371/journal.pone.0134768
– ident: e_1_2_7_96_1
  doi: 10.1126/science.2858129
– ident: e_1_2_7_7_1
  doi: 10.3892/mmr.2014.2384
– ident: e_1_2_7_181_1
  doi: 10.3109/0886022X.2012.656563
– ident: e_1_2_7_274_1
  doi: 10.1586/14760584.2015.1026808
– ident: e_1_2_7_110_1
  doi: 10.1136/oem.60.4.237
– ident: e_1_2_7_225_1
  doi: 10.1016/j.freeradbiomed.2012.02.005
– ident: e_1_2_7_74_1
  doi: 10.1111/j.1742-7835.2007.00125.x
– ident: e_1_2_7_79_1
  doi: 10.1177/0394632016651447
– ident: e_1_2_7_222_1
  doi: 10.1002/mnfr.201000206
– ident: e_1_2_7_24_1
  doi: 10.1371/journal.pone.0052164
– ident: e_1_2_7_115_1
  doi: 10.1371/journal.pone.0029102
– ident: e_1_2_7_103_1
  doi: 10.1371/journal.pone.0069452
– ident: e_1_2_7_249_1
  doi: 10.4236/jbbs.2012.22021
– ident: e_1_2_7_252_1
  doi: 10.1007/s11064-004-6883-z
– ident: e_1_2_7_161_1
  doi: 10.1007/s10571-011-9752-8
– ident: e_1_2_7_207_1
  doi: 10.1080/02652030500309319
– ident: e_1_2_7_32_1
  doi: 10.1667/RR1190.1
– ident: e_1_2_7_276_1
  doi: 10.3892/etm.2013.1381
– ident: e_1_2_7_129_1
  doi: 10.5271/sjweh.159
– year: 2014
  ident: e_1_2_7_112_1
  article-title: Effect of Saffron extract on Acrylamide‐induced toxicity: In vitro and in vivo assessment
  publication-title: Chinese Journal of Integrative Medicine
– volume: 55
  start-page: 467
  issue: 2
  year: 2004
  ident: e_1_2_7_178_1
  article-title: The protective effects of resveratrol against changes in blood platelet thiols induced by platinum compounds
  publication-title: Journal of Physiology and Pharmacology
– ident: e_1_2_7_277_1
  doi: 10.1080/20024091064165
– ident: e_1_2_7_212_1
  doi: 10.1016/j.taap.2014.08.011
– ident: e_1_2_7_50_1
  doi: 10.1016/j.neuint.2010.11.011
– ident: e_1_2_7_55_1
  doi: 10.1177/0960327112468178
– ident: e_1_2_7_248_1
  doi: 10.1111/j.1753-4887.2010.00335.x
– ident: e_1_2_7_5_1
  doi: 10.1002/ptr.5570
– ident: e_1_2_7_132_1
  doi: 10.1016/j.toxlet.2012.04.001
– ident: e_1_2_7_197_1
  doi: 10.1186/s40199-015-0112-y
– ident: e_1_2_7_223_1
  doi: 10.1177/0748233714566874
– ident: e_1_2_7_149_1
  doi: 10.1039/C5TX00260E
– ident: e_1_2_7_214_1
  doi: 10.4103/0974-1208.138867
– ident: e_1_2_7_68_1
  doi: 10.1016/j.freeradbiomed.2014.06.011
– volume: 8
  start-page: 891
  issue: 4
  year: 2011
  ident: e_1_2_7_195_1
  article-title: Resveratrol mediated protection of dacarbazine‐induced mutagenicity in mice
  publication-title: Life Science Journal
– volume: 3
  start-page: 377
  issue: 5
  year: 2009
  ident: e_1_2_7_77_1
  article-title: Investigation on the protective effect of grape seed and Linseed oils against ciclophosphamide induced genotoxicity in mice
  publication-title: Global Veterinaria
– ident: e_1_2_7_158_1
– ident: e_1_2_7_270_1
  doi: 10.1016/j.fct.2009.02.006
– ident: e_1_2_7_114_1
  doi: 10.1002/tox.20734
– ident: e_1_2_7_280_1
  doi: 10.1211/0022357056523
– ident: e_1_2_7_146_1
  doi: 10.1093/toxsci/kfn120
– ident: e_1_2_7_170_1
  doi: 10.1371/journal.pone.0014575
– ident: e_1_2_7_102_1
  doi: 10.1038/sj.bjp.0705688
– volume: 16
  start-page: 120
  issue: 2
  year: 2008
  ident: e_1_2_7_14_1
  article-title: The effects of oral grape seed extract on cisplatin‐induced cytogenotoxicity in mice
  publication-title: Saudi Pharmaceutical Journal
– ident: e_1_2_7_108_1
  doi: 10.1016/j.pupt.2008.04.004
– ident: e_1_2_7_198_1
  doi: 10.15171/apb.2016.055
– ident: e_1_2_7_130_1
  doi: 10.1098/rstb.2008.0208
– ident: e_1_2_7_227_1
  doi: 10.3109/15376516.2011.556156
– ident: e_1_2_7_83_1
  doi: 10.1016/j.fct.2013.03.031
– ident: e_1_2_7_255_1
  doi: 10.1016/S0889-857X(05)70365-3
– ident: e_1_2_7_104_1
  doi: 10.1016/j.etap.2016.07.010
– ident: e_1_2_7_107_1
  doi: 10.1007/s00411-013-0461-1
– ident: e_1_2_7_12_1
  doi: 10.1016/j.fct.2014.05.011
– ident: e_1_2_7_72_1
  doi: 10.1111/j.1742-7843.2006.pto_497.x
– ident: e_1_2_7_17_1
  doi: 10.1038/aja.2011.76
– ident: e_1_2_7_80_1
  doi: 10.1016/j.etap.2009.05.013
– volume: 5
  start-page: 6076
  issue: 25
  year: 2011
  ident: e_1_2_7_101_1
  article-title: Grape seed extract mitigates garlic‐induced oxidative stress in rat spleen and plasma
  publication-title: Journal of Medicinal Plant Research
– ident: e_1_2_7_180_1
  doi: 10.1186/s12935-014-0152-2
– ident: e_1_2_7_10_1
  doi: 10.1016/j.cbi.2014.12.035
– ident: e_1_2_7_201_1
  doi: 10.1155/2011/703676
– ident: e_1_2_7_31_1
  doi: 10.1007/s00204-003-0538-8
– volume: 163
  start-page: 539
  issue: 11
  year: 2012
  ident: e_1_2_7_124_1
  article-title: Protective antioxidant effects of grape seed extract in a cisplatin‐induced hepatotoxicity model in rabbits
  publication-title: Revue de Médecine Vétérinaire
– ident: e_1_2_7_232_1
  doi: 10.1002/ptr.5805
– ident: e_1_2_7_143_1
  doi: 10.3390/ijms15011625
– ident: e_1_2_7_93_1
  doi: 10.1371/journal.pone.0021565
– volume: 28
  start-page: 321
  issue: 3
  year: 2007
  ident: e_1_2_7_19_1
  article-title: Effects of long‐term use of fluoxetine on fertility parameters in adult male rats
  publication-title: Neuro Endocrinology Letters
– ident: e_1_2_7_140_1
  doi: 10.3136/fstr.22.403
– ident: e_1_2_7_193_1
  doi: 10.1002/jcb.25242
– ident: e_1_2_7_244_1
  doi: 10.4103/0253-7613.16216
– volume: 63
  start-page: 293
  issue: 3
  year: 2012
  ident: e_1_2_7_100_1
  article-title: Resveratrol protects against acute chemotherapy toxicity induced by doxorubucin in rat erythrocyte and plasma
  publication-title: Journal of Physiology and Pharmacology
– ident: e_1_2_7_125_1
  doi: 10.2174/157015911795017353
– ident: e_1_2_7_49_1
  doi: 10.1007/s00204-004-0566-z
– ident: e_1_2_7_63_1
  doi: 10.15537/smj.2016.4.13611
– volume: 16
  start-page: 2
  year: 2017
  ident: e_1_2_7_234_1
  article-title: Black seed (Nigella Sativa) and its constituent thymoquinone as an antidote or a protective agent against natural or chemical toxicities
  publication-title: Iranian Journal of Pharmaceutical Research
– ident: e_1_2_7_264_1
  doi: 10.1007/s12011-011-9272-x
– volume: 2014
  start-page: 698628
  issue: 6
  year: 2014
  ident: e_1_2_7_13_1
  article-title: Effect of resveratrol on hematological and biochemical alterations in rats exposed to fluoride
  publication-title: BioMed Research International
– volume: 12
  start-page: 57
  issue: 3
  year: 2006
  ident: e_1_2_7_88_1
  article-title: Cellular mechanisms of lead neurotoxicity
  publication-title: Medical Science Monitor
– ident: e_1_2_7_210_1
  doi: 10.1016/j.ecoenv.2007.08.023
– volume: 36
  start-page: 217
  issue: 4
  year: 2003
  ident: e_1_2_7_46_1
  article-title: Fluoride and oxidative stress
  publication-title: Fluoride
– ident: e_1_2_7_238_1
  doi: 10.2165/11316640-000000000-00000
– ident: e_1_2_7_172_1
  doi: 10.1002/ptr.5644
– ident: e_1_2_7_187_1
  doi: 10.1007/s00420-003-0458-1
– ident: e_1_2_7_69_1
  doi: 10.1007/s10534-012-9592-0
– ident: e_1_2_7_44_1
  doi: 10.1016/j.fct.2013.05.030
– ident: e_1_2_7_59_1
  doi: 10.1038/ki.2008.129
– ident: e_1_2_7_118_1
  doi: 10.1016/j.jphotobiol.2016.03.027
– ident: e_1_2_7_257_1
  doi: 10.1111/j.1745-4514.2009.00276.x
– ident: e_1_2_7_165_1
  doi: 10.1186/1742-2094-8-163
– ident: e_1_2_7_216_1
  doi: 10.1080/01483919008049014
– ident: e_1_2_7_29_1
  doi: 10.1016/j.jchromb.2003.10.057
– ident: e_1_2_7_199_1
  doi: 10.1002/jat.916
– ident: e_1_2_7_106_1
  doi: 10.1124/jpet.112.194142
– ident: e_1_2_7_157_1
  doi: 10.1155/2014/398285
– ident: e_1_2_7_105_1
  doi: 10.1007/s10616-013-9589-8
– ident: e_1_2_7_261_1
  doi: 10.1155/2014/137919
– ident: e_1_2_7_213_1
  doi: 10.1139/cjpp-2015-0088
– ident: e_1_2_7_25_1
  doi: 10.1016/j.neuro.2015.05.005
– ident: e_1_2_7_38_1
  doi: 10.1016/j.bbadis.2006.10.019
– ident: e_1_2_7_150_1
  doi: 10.18632/oncotarget.14056
– ident: e_1_2_7_251_1
  doi: 10.1089/cbr.2009.0679
– ident: e_1_2_7_218_1
  doi: 10.1002/mc.22099
– ident: e_1_2_7_78_1
  doi: 10.1111/fcp.12205
– ident: e_1_2_7_263_1
  doi: 10.3390/molecules200712250
– ident: e_1_2_7_173_1
  doi: 10.1006/enrs.2002.4352
– ident: e_1_2_7_76_1
  doi: 10.1002/jlcr.3368
– ident: e_1_2_7_52_1
  doi: 10.1097/00002030-200304001-00004
– volume: 28
  start-page: 272
  issue: 4
  year: 2015
  ident: e_1_2_7_138_1
  article-title: Grape seed proanthocyanidin extract alleviates arsenic‐induced oxidative reproductive toxicity in male mice
  publication-title: Biomedical and Environmental Sciences
– ident: e_1_2_7_163_1
  doi: 10.1016/j.toxrep.2015.11.010
– ident: e_1_2_7_53_1
  doi: 10.1002/jnr.23453
– ident: e_1_2_7_26_1
  doi: 10.1002/cbf.2907
– ident: e_1_2_7_133_1
  doi: 10.1097/00008877-200609000-00014
– ident: e_1_2_7_136_1
  doi: 10.1016/j.biocel.2011.06.010
– volume-title: Environmental health criteria 202: Selected non‐heterocyclic polycyclic aromatic hydrocarbons, international programme on chemical safety (IPCS)
  year: 1998
  ident: e_1_2_7_119_1
– ident: e_1_2_7_259_1
  doi: 10.1016/j.bbadis.2015.03.009
– ident: e_1_2_7_92_1
  doi: 10.18174/388693
– volume: 18
  start-page: 159
  issue: 1
  year: 1982
  ident: e_1_2_7_162_1
  article-title: Compensatory mechanisms in the nigrostriatal dopaminergic system in Parkinson's disease: Studies in an animal model
  publication-title: Israel Journal of Medical Sciences
– ident: e_1_2_7_56_1
  doi: 10.3109/15376516.2014.881944
– ident: e_1_2_7_141_1
  doi: 10.1093/brain/awg014
– ident: e_1_2_7_241_1
  doi: 10.1177/0748233711414614
– volume: 69
  start-page: 933
  issue: 5
  year: 2012
  ident: e_1_2_7_215_1
  article-title: Hepatoprotective activity of Vitis vinifera root extract against carbon tetrachloride‐induced liver damage in rats
  publication-title: Acta Poloniae Pharmaceutica
– ident: e_1_2_7_47_1
  doi: 10.1016/j.etap.2015.11.018
– ident: e_1_2_7_57_1
  doi: 10.1016/j.lfs.2007.06.032
– ident: e_1_2_7_117_1
  doi: 10.1248/bpb.32.876
– ident: e_1_2_7_64_1
  doi: 10.3390/toxins7010097
– ident: e_1_2_7_272_1
  doi: 10.1016/j.fct.2012.12.052
– ident: e_1_2_7_189_1
  doi: 10.1016/j.neuro.2007.03.008
– ident: e_1_2_7_16_1
  doi: 10.1016/j.taap.2016.04.016
– ident: e_1_2_7_196_1
  doi: 10.1016/j.fct.2016.11.035
– ident: e_1_2_7_219_1
  doi: 10.1615/JEnvironPatholToxicolOncol.v20.i2.70
– ident: e_1_2_7_43_1
  doi: 10.1002/em.21919
– ident: e_1_2_7_139_1
  doi: 10.1111/j.1742-7843.2008.00358.x
– ident: e_1_2_7_174_1
  doi: 10.1016/j.cbi.2015.10.005
– ident: e_1_2_7_9_1
  doi: 10.3109/13880209.2012.729065
– ident: e_1_2_7_236_1
  doi: 10.1016/0006-2952(93)90319-R
– ident: e_1_2_7_229_1
  doi: 10.1002/biof.1221
– ident: e_1_2_7_208_1
  doi: 10.1007/s00210-014-0994-0
– ident: e_1_2_7_153_1
  doi: 10.1016/j.cbi.2005.07.004
– ident: e_1_2_7_154_1
  doi: 10.4162/nrp.2015.9.1.37
– ident: e_1_2_7_144_1
  doi: 10.1021/acs.chemrestox.6b00001
– ident: e_1_2_7_185_1
  doi: 10.1111/1523-1747.ep12260588
– ident: e_1_2_7_228_1
  doi: 10.1248/bpb.27.1459
– ident: e_1_2_7_66_1
  doi: 10.1016/j.ejphar.2008.06.068
– ident: e_1_2_7_175_1
  doi: 10.1016/j.ajpath.2013.08.011
– ident: e_1_2_7_54_1
  doi: 10.1089/jmf.2013.2834
– ident: e_1_2_7_188_1
  doi: 10.1016/j.jns.2007.06.037
– ident: e_1_2_7_37_1
  doi: 10.1002/jat.1103
– ident: e_1_2_7_275_1
  doi: 10.1124/mol.110.064535
– ident: e_1_2_7_235_1
  doi: 10.1016/j.tig.2006.07.008
SSID ssj0009204
Score 2.4619653
SecondaryResourceType review_article
Snippet Vitis vinifera (grape) is one of the “most‐produced fruit” in the world. Grape seeds are a valuable source of phenolic compounds including resveratrol (RSV)....
Vitis vinifera (grape) is one of the “most‐produced fruit” in the world. Grape seeds are a valuable source of phenolic compounds including resveratrol (RSV)....
Vitis vinifera (grape) is one of the "most-produced fruit" in the world. Grape seeds are a valuable source of phenolic compounds including resveratrol (RSV)....
SourceID proquest
pubmed
crossref
wiley
SourceType Aggregation Database
Index Database
Enrichment Source
Publisher
StartPage 2164
SubjectTerms Animals
Antioxidants - pharmacology
Biocompatibility
Biological activity
Cancer
Carbon tetrachloride
Cardiovascular diseases
chemical toxins
Clinical trials
Constituents
enzyme activity
Fruit - chemistry
Glutathione
Glutathione peroxidase
grape seeds
Grapes
Heart diseases
Homeostasis
Humans
in vitro studies
In vivo methods and tests
Inflammatory diseases
Intoxication
Lipopolysaccharides
Malondialdehyde
Medical research
Metals
Mycotoxins
natural toxicants
natural toxins
neoplasms
Organic chemistry
Organs
Oxidation
Peroxidase
Phenolic compounds
Phenols
Phenols - pharmacology
Physiological effects
Plant Extracts - pharmacology
poisoning
Protective Agents - pharmacology
protective effect
protective effects
Resveratrol
Reviews
Seeds
Stilbenes - pharmacology
Superoxide dismutase
Toxicity
Toxins
Triptolide
Vitis - chemistry
Vitis vinifera
Title Protective effects of Vitis vinifera (grapes) and one of its biologically active constituents, resveratrol, against natural and chemical toxicities: A comprehensive review
URI https://onlinelibrary.wiley.com/doi/abs/10.1002%2Fptr.6168
https://www.ncbi.nlm.nih.gov/pubmed/30088293
https://www.proquest.com/docview/2129860930
https://www.proquest.com/docview/2085661532
https://www.proquest.com/docview/2189518141
Volume 32
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1ti9NAEF7kEPGLL_WtesoIUhWaXpJNNhu_neJxCCfl6EnBD2Gzu9FiaY4kPax_yT_pTDZpOd8QP_VDpstsMrvzTPLMs4w9kzKNTBQmno-5xENIbT1pY-mJWNkE01EcF1QonrwXx2fRu3k871iV1Avj9CG2L9xoZbT7NS1wldcHO9HQ86aaiEBQny9RtQgPne6Uo9KwPTmwPUU-CuS81531w4P-j5cz0S_w8jJabdPN0U32sXfUsUy-TNZNPtHfftJw_L-Z3GI3OhQKhy5sbrMrdjVgV1-XiBQ3A3btpPvgPmCjqZO23oxhtuvUqscwgulO9Hpzh32fOsEH3Dyh44hAWcAHkkyCi0XLoFHwgvSxbf0S1MpAubJkskBLJwVF8bLcgHKj6NLxGIjpMYbK1hek_1yVyzGoT2qBF6FVJcV50Gi6Uz6ApvyKzpNO7Cs4BKLMV_azo-mDa9S5y86O3s7eHHvdQRCe5lgRejaMTGgKHhY8EBaziyySXOog1z7nJlZKxjoyccoNtybhIc8TZf08EQXH6srX_B7bW-GkHjCQRVRYvAmhFjwS3KgiR9BlOM-xUDYiGLLnfVBkulNJp8M6lpnTdw4zfFoZPa0he7q1PHfKIL-x2e_jKuv2hjpDsJBK4afcxyG2l3FV06catbLlGm0QCQvC4uFfbAKJ0S2DCJ2-72J26wj3qXRK-ZCN2sj7o4fZdHZKvw__1fARu46YUbp2zH2211Rr-xhxWZM_aVfgD3BIOD8
linkProvider Wiley-Blackwell
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3db9MwED-NgYAXPspXYYCRUBlS0yV24jjwNBBTgXWqpg71ASlyYgcqqmRK04nyL_FPco6TVuNLiKc8-GKdk7Pvd_b5dwBPhYh85dPQcdGXOAiptSN0IBweSB2iOwqCzASKoyM-PPHfTYPpFrxs78JYfoj1hpuZGfV6bSa42ZDe27CGnlblgHtcXICLpqB3HU8db7ijIlrXDqzryPuemLbMsy7da98874t-AZjn8WrtcA6uw8dWVZtn8mWwrJJB-u0nFsf_HMsNuNYAUbJvLecmbOm8A5deFQgWVx24PGrO3DvQG1t261WfTDaXtRZ90iPjDe_16hZ8H1vOB1w_SZMmQoqMfDCsSeRsVifRSLJrKLL14jmRuSJFro3IDCUtG5QxmfmKSNtLWthUBpPs0SelXpwZCuiymPeJ_CRn2EhqYlIch-ktbcgPSFV8ReUNVewLsk9M1nypP9tMfWLv6tyGk4M3k9dDp6kF4aQMg0JHU19RlTGaMY9rdDAiCxOReknqMqYCKUWQ-iqImGJahYyyJJTaTUKeMQyw3JTdge0cB3UPiMj8TONHoClnPmdKZgniLsVYgrGy4l4XnrVWEacNUbqp1zGPLcUzjfFvxeZvdeHJWvLUkoP8RmanNay4WR4WMeKFSHA3Yi52sW7GiW1Oa2SuiyXKIBjmBo7Tv8h4As1beD4qfdca7VoR5proKWJd6NWm90cN4_Hk2Dzv_6vgY7gynIwO48O3R-8fwFWEkMLeztyB7apc6ocI06rkUT0dfwC-MDxa
linkToPdf http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnZ1bb9MwFMctGGjihUu5rDDASKiA1HSJ7TgOb4NRjcumaupQJR4ix3ZGRZVUaTpRvhJfkuM4aTVuQjz1IafWcXLs83dy_DNCT4WImWYk8nzIJR5IauMJEwqPh9JEkI7CMLMLxaNjfnjK3k3CSVNVaffCOD7E-oWbHRn1fG0H-Fxnexto6LwqBzzg4jK6wrgvbEQfnGzQUTGpjw6sj5FngZi04Fmf7LX_vJiKftGXF-VqnW-GN9Cn1lNXZvJlsKzSgfr2E8Tx_7pyE11vZCjed3FzC10yeQddfVWAVFx10PZR88W9g3ojx7Ze9fF4s1Vr0cc9PNpQr1e30feRIz7A7ImbIhFcZPijZSbh82ldQiPxcwvINosXWOYaF7mxJlOwdCwoGzCzFZauFVW4QgZb6tHHpVmcWwB0Wcz6WJ7JKVzENZYU-mFbUw36AFfFV3DegmJf4n1sa-ZL89nV6WO3U-cOOh2-Gb8-9JqTIDxFYUnoGcI00RklGQ24gfQisigVKkiVT6kOpRShYjqMqaZGR5TQNJLGTyOeUVhe-YreRVs5dGoHYZGxzMBNIIpTxqmWWQqqS1OawkpZ86CLnrVBkagGk25P65glDvBMEnhaiX1aXfRkbTl3aJDf2Oy2cZU0k8MiAbUQC-7H1Icm1pdhWNtvNTI3xRJsQApzK8bJX2wCAdEtAgZO33Mxu3aE-nbtFNMu6tWR90cPk9H4xP7e_1fDx2h7dDBMPrw9fv8AXQP9KNzWzF20VZVL8xA0WpU-qgfjDwlSOxI
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Protective+effects+of+Vitis+vinifera+%28grapes%29+and+one+of+its+biologically+active+constituents%2C+resveratrol%2C+against+natural+and+chemical+toxicities%3A+A+comprehensive+review&rft.jtitle=Phytotherapy+research&rft.au=Tabeshpour%2C+Jamshid&rft.au=Mehri%2C+Soghra&rft.au=Behbahani%2C+Fatemeh+Shaebani&rft.au=Hosseinzadeh%2C+Hossein&rft.date=2018-11-01&rft.pub=Wiley+Subscription+Services%2C+Inc&rft.issn=0951-418X&rft.eissn=1099-1573&rft.volume=32&rft.issue=11&rft.spage=2164&rft.epage=2190&rft_id=info:doi/10.1002%2Fptr.6168&rft.externalDBID=NO_FULL_TEXT
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0951-418X&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0951-418X&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0951-418X&client=summon