Hyperoside: A review on its sources, biological activities, and molecular mechanisms
Hyperoside is a natural flavonol glycoside in various plants, such as Crataegus pinnatifida Bge, Forsythia suspensa, and Cuscuta chinensis Lam. Medical research has found that hyperoside possesses a broad spectrum of biological activities, including anticancer, anti‐inflammatory, antibacterial, anti...
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| Published in | Phytotherapy research Vol. 36; no. 7; pp. 2779 - 2802 |
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| Main Authors | , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
Chichester, UK
John Wiley & Sons, Ltd
01.07.2022
Wiley Subscription Services, Inc |
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| Online Access | Get full text |
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| Abstract | Hyperoside is a natural flavonol glycoside in various plants, such as Crataegus pinnatifida Bge, Forsythia suspensa, and Cuscuta chinensis Lam. Medical research has found that hyperoside possesses a broad spectrum of biological activities, including anticancer, anti‐inflammatory, antibacterial, antiviral, antidepressant, and organ protective effects. These pharmacological properties lay the foundation for its use in treating multiple diseases, such as sepsis, arthritis, colitis, diabetic nephropathy, myocardial ischemia–reperfusion, pulmonary fibrosis, and cancers. Hyperoside is obtained from the plants and chemical synthesis. This study aims to provide a comprehensive overview of hyperoside on its sources and biological activities to provide insights into its therapeutic potential, and to provide a basis for high‐quality studies to determine the clinical efficacy of this compound. |
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| AbstractList | Hyperoside is a natural flavonol glycoside in various plants, such as
Crataegus pinnatifida
Bge,
Forsythia suspensa
, and
Cuscuta chinensis
Lam. Medical research has found that hyperoside possesses a broad spectrum of biological activities, including anticancer, anti‐inflammatory, antibacterial, antiviral, antidepressant, and organ protective effects. These pharmacological properties lay the foundation for its use in treating multiple diseases, such as sepsis, arthritis, colitis, diabetic nephropathy, myocardial ischemia–reperfusion, pulmonary fibrosis, and cancers. Hyperoside is obtained from the plants and chemical synthesis. This study aims to provide a comprehensive overview of hyperoside on its sources and biological activities to provide insights into its therapeutic potential, and to provide a basis for high‐quality studies to determine the clinical efficacy of this compound. Hyperoside is a natural flavonol glycoside in various plants, such as Crataegus pinnatifida Bge, Forsythia suspensa, and Cuscuta chinensis Lam. Medical research has found that hyperoside possesses a broad spectrum of biological activities, including anticancer, anti‐inflammatory, antibacterial, antiviral, antidepressant, and organ protective effects. These pharmacological properties lay the foundation for its use in treating multiple diseases, such as sepsis, arthritis, colitis, diabetic nephropathy, myocardial ischemia–reperfusion, pulmonary fibrosis, and cancers. Hyperoside is obtained from the plants and chemical synthesis. This study aims to provide a comprehensive overview of hyperoside on its sources and biological activities to provide insights into its therapeutic potential, and to provide a basis for high‐quality studies to determine the clinical efficacy of this compound. Hyperoside is a natural flavonol glycoside in various plants, such as Crataegus pinnatifida Bge, Forsythia suspensa, and Cuscuta chinensis Lam. Medical research has found that hyperoside possesses a broad spectrum of biological activities, including anticancer, anti-inflammatory, antibacterial, antiviral, antidepressant, and organ protective effects. These pharmacological properties lay the foundation for its use in treating multiple diseases, such as sepsis, arthritis, colitis, diabetic nephropathy, myocardial ischemia-reperfusion, pulmonary fibrosis, and cancers. Hyperoside is obtained from the plants and chemical synthesis. This study aims to provide a comprehensive overview of hyperoside on its sources and biological activities to provide insights into its therapeutic potential, and to provide a basis for high-quality studies to determine the clinical efficacy of this compound.Hyperoside is a natural flavonol glycoside in various plants, such as Crataegus pinnatifida Bge, Forsythia suspensa, and Cuscuta chinensis Lam. Medical research has found that hyperoside possesses a broad spectrum of biological activities, including anticancer, anti-inflammatory, antibacterial, antiviral, antidepressant, and organ protective effects. These pharmacological properties lay the foundation for its use in treating multiple diseases, such as sepsis, arthritis, colitis, diabetic nephropathy, myocardial ischemia-reperfusion, pulmonary fibrosis, and cancers. Hyperoside is obtained from the plants and chemical synthesis. This study aims to provide a comprehensive overview of hyperoside on its sources and biological activities to provide insights into its therapeutic potential, and to provide a basis for high-quality studies to determine the clinical efficacy of this compound. |
| Author | Zhou, Chang‐Zheng Wei, Hao‐Cheng Wan, Xin‐Huan Li, Ying Zheng, Ting‐Ting Wang, Qi Zhou, Sheng‐Jun |
| Author_xml | – sequence: 1 givenname: Qi surname: Wang fullname: Wang, Qi organization: Shandong University of Traditional Chinese Medicine – sequence: 2 givenname: Hao‐Cheng surname: Wei fullname: Wei, Hao‐Cheng organization: Shandong University of Traditional Chinese Medicine – sequence: 3 givenname: Sheng‐Jun surname: Zhou fullname: Zhou, Sheng‐Jun organization: Shandong University of Traditional Chinese Medicine – sequence: 4 givenname: Ying surname: Li fullname: Li, Ying organization: Shandong University of Traditional Chinese Medicine – sequence: 5 givenname: Ting‐Ting surname: Zheng fullname: Zheng, Ting‐Ting organization: Shandong University of Traditional Chinese Medicine – sequence: 6 givenname: Chang‐Zheng orcidid: 0000-0002-8874-106X surname: Zhou fullname: Zhou, Chang‐Zheng email: szyzcz@sina.com organization: Shandong University of Traditional Chinese Medicine – sequence: 7 givenname: Xin‐Huan surname: Wan fullname: Wan, Xin‐Huan email: wan20073212@163.com organization: Shandong University of Traditional Chinese Medicine |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/35561084$$D View this record in MEDLINE/PubMed |
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| Notes | Qi Wang, Hao‐Cheng Wei, and Sheng‐Jun, Zhou contributed equally to this work. Funding information This research was funded by Shandong Provincial Natural Science Foundation, China, Grant/Award Number: ZR2021QH232, ZR2020MB108 ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 ObjectType-Review-3 content type line 23 |
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| Snippet | Hyperoside is a natural flavonol glycoside in various plants, such as Crataegus pinnatifida Bge, Forsythia suspensa, and Cuscuta chinensis Lam. Medical... Hyperoside is a natural flavonol glycoside in various plants, such as Crataegus pinnatifida Bge, Forsythia suspensa , and Cuscuta chinensis Lam. Medical... |
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| SubjectTerms | Anticancer properties Antidepressants Antiviral drugs Arthritis biological activities biomedical research Chemical synthesis Colitis Crataegus pinnatifida Cuscuta Diabetes mellitus Diabetic nephropathy extraction Fibrosis Flavonols Forsythia suspensa glycosides hyperoside Inflammation Ischemia Lung diseases Medical research Molecular modelling Myocardial ischemia Nephropathy phytotherapy pulmonary fibrosis Reperfusion Sepsis synthesis |
| Title | Hyperoside: A review on its sources, biological activities, and molecular mechanisms |
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