Multimodal Imaging Guided Photothermal Therapy using Functionalized Graphene Nanosheets Anchored with Magnetic Nanoparticles

• Published in: Advanced materials (Weinheim) Vol. 24; no. 14; pp. 1868 - 1872
• Main Authors: Yang, Kai, Hu, Lilei, Ma, Xingxing, Ye, Shuoqi, Cheng, Liang, Shi, Xiaoze, Li, Changhui, Li, Yonggang, Liu, Zhuang
• Format: Journal Article
• Language: English
• Published: Weinheim WILEY-VCH Verlag 10.04.2012; WILEY‐VCH Verlag
• Subjects: Animals; Ferric Compounds - chemistry; graphene oxide nanocomposites; Graphite - chemistry; Magnetic Resonance Imaging; Magnetite Nanoparticles - chemistry; Magnetite Nanoparticles - therapeutic use; Mice; multimodal imaging; Nanocomposites - chemistry; Nanocomposites - therapeutic use; Neoplasms - diagnosis; Neoplasms - therapy; Oxidation-Reduction; Oxides - chemistry; photoacoustic imaging; Phototherapy; photothermal therapy; Polyethylene Glycols - chemistry

In this work, a nanoscale reduced graphene oxide–iron oxide nanoparticle (RGO–IONP) complex is noncovalently functionalized with polyethylene glycol (PEG), obtaining a RGO–IONP–PEG nanocomposite with excellent physiological stability, strong NIR optical absorbance, and superparamagnetic properties....