Factors Enhancing Treatment of Hepatitis C Virus–Infected Italian People Who Use Drugs: The CLEO-GRECAS Experience

• Published in: The American journal of gastroenterology Vol. 116; no. 6; pp. 1248 - 1255
• Main Authors: Rinaldi, Luca, Messina, Vincenzo, Di Marco, Vito, Iovinella, Vincenzo, Claar, Ernesto, Cariti, Giuseppe, Sacco, Rodolfo, De Luca, Massimo, Scifo, Gaetano, Gatti, Pietro, Barbarini, Giorgio, Pace Palitti, Valeria, Quartini, Mariano, Tundo, Paolo, D'Offizi, Gianpiero, Parruti, Giustino, di Rosolini, Maria Antonietta, Garrucciu, Giovanni, Cosco, Lucio, Benanti, Francesco, Gimignani, Giancarlo, Vespasiani Gentilucci, Umberto, Di Lorenzo, Francesco, D'Antò, Maria, Nevola, Riccardo, Lupia, Tommaso, Rosato, Valerio, Morbiducci, Valeria, Luzzitelli, Ilaria, Sozio, Federica, Di Stefano, Marco, Ciraci, Emanuela, Bulla, Fabio, Guarisco, Riccardo, Cangiano, Cecilia, Imparato, Michele, Maggi, Paolo, Ascione, Antonio, Craxì, Antonio, Izzi, Antonio
• Format: Journal Article
• Language: English
• Published: United States Wolters Kluwer 01.06.2021; Wolters Kluwer Health Medical Research, Lippincott Williams & Wilkins
• Subjects: Adult; Alcohol; Antiviral Agents - therapeutic use; Antiviral drugs; Drug addiction; Female; Gastroenterology; Genotype & phenotype; Hepatitis B; Hepatitis C; Hepatitis C, Chronic - drug therapy; Hepatitis C, Chronic - epidemiology; Hepatology; HIV; Human immunodeficiency virus; Humans; Infections; Intention to Treat Analysis; Interdisciplinary aspects; Italy; Liver diseases; Male; Medication Adherence; Middle Aged; Performance evaluation; Prospective Studies; Retrospective Studies; Substance abuse treatment; Substance-Related Disorders - complications; Substance-Related Disorders - epidemiology; Sustained Virologic Response; Ultrasonic imaging; Womens health; Italy

We assessed the performance of direct-acting antivirals (DAAs) in hepatitis C virus (HCV)-infected people who use drugs (PWUDs) in terms of sustained virological response (SVR) and adherence rates in comparison to a location-matched cohort of non-PWUD HCV patients. All consecutive HCV RNA-positive P...