Acute cardiovascular effects of bitter orange extract (p‐synephrine) consumed alone and in combination with caffeine in human subjects: A placebo‐controlled, double‐blind study

• Published in: Phytotherapy research Vol. 32; no. 1; pp. 94 - 102
• Main Authors: Ratamess, Nicholas A., Bush, Jill A., Stohs, Sidney J., Ellis, Nicole L., Vought, Ira T., O'Grady, Elizabeth A., Kuper, Jeremy D., Hasan, Saif B., Kang, Jie, Faigenbaum, Avery D.
• Format: Journal Article
• Language: English
• Published: England Wiley Subscription Services, Inc 01.01.2018
• Subjects: Blood pressure; Caffeine; Cardiovascular system; Citrus aurantium; clinical trials; diastolic blood pressure; Double-blind studies; Heart rate; humans; mean arterial pressure; placebos; p‐synephrine; Supplements; systolic blood pressure; blood pressure; caffeine; heart rate; Citrus aurantium; p-synephrine; mean arterial pressure

The purpose was to examine cardiovascular responses to supplementation with p‐synephrine alone and in combination with caffeine during quiet sitting. Sixteen subjects were given (in double‐blind manner) either 103 mg of p‐synephrine (S), 233 mg of caffeine +104 mg of p‐synephrine (LC + S), 240 mg of...