Total Synthesis of Bryostatin 8 Using an Organosilane‐Based Strategy

Convergent total synthesis of bryostatin 8 has been accomplished by an organosilane‐based strategy. The C ring is constructed stereoselectively through a geminal bis(silane)‐based [1,5]‐Brook rearrangement, and the B ring through geminal bis(silane)‐based Prins cyclization, thus efficiently joining...

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Published inAngewandte Chemie International Edition Vol. 57; no. 4; pp. 942 - 946
Main Authors Zhang, Yuebao, Guo, Qianyou, Sun, Xianwei, Lu, Ji, Cao, Yanjun, Pu, Qiang, Chu, Zhiwen, Gao, Lu, Song, Zhenlei
Format Journal Article
LanguageEnglish
Published WEINHEIM Wiley 22.01.2018
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