Total Synthesis of Bryostatin 8 Using an Organosilane‐Based Strategy
Convergent total synthesis of bryostatin 8 has been accomplished by an organosilane‐based strategy. The C ring is constructed stereoselectively through a geminal bis(silane)‐based [1,5]‐Brook rearrangement, and the B ring through geminal bis(silane)‐based Prins cyclization, thus efficiently joining...
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Published in | Angewandte Chemie International Edition Vol. 57; no. 4; pp. 942 - 946 |
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Main Authors | , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
WEINHEIM
Wiley
22.01.2018
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Subjects | |
Online Access | Get full text |
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