Dermatoses in five related female carriers of X-linked chronic granulomatous disease

Eight female members of a family with X-linked chronic granulomatous disease were identified. Five were shown to be carriers of the disease gene. Each of these female carriers of the gene had a history of skin eruptions. The identification of the carrier state is important as genetic counselling sho...

Full description

Saved in:
Bibliographic Details
Published inBritish journal of dermatology (1951) Vol. 121; no. 3; p. 391
Main Authors Garioch, J J, Sampson, J R, Seywright, M, Thomson, J
Format Journal Article
LanguageEnglish
Published England 01.09.1989
Subjects
Adult
Female
Genetic Carrier Screening - methods
Genetic Linkage
Granulomatous Disease, Chronic - complications
Granulomatous Disease, Chronic - genetics
Humans
Pedigree
Skin Diseases - etiology
Skin Diseases - genetics
X Chromosome
Online AccessGet more information

Cover

More Information
Summary:Eight female members of a family with X-linked chronic granulomatous disease were identified. Five were shown to be carriers of the disease gene. Each of these female carriers of the gene had a history of skin eruptions. The identification of the carrier state is important as genetic counselling should be offered and the prenatal diagnosis of this disorder is possible.
ISSN:0007-0963
DOI:10.1111/j.1365-2133.1989.tb01434.x