Role of non-human primate models in accelerating research and developing countermeasures against Zika virus infection

• Published in: The Lancet. Microbe Vol. 6; no. 6; p. 101030
• Main Authors: Li, Amanda, Coffey, Lark L, Mohr, Emma L, Raper, Jessica, Chahroudi, Ann, Ausderau, Karla K, Aliota, Matthew T, Friedrich, Thomas C, Mitzey, Ann M, Koenig, Michelle R, Golos, Thaddeus G, Jaeger, Hannah K, Roberts, Victoria H J, Lo, Jamie O, Smith, Jessica L, Hirsch, Alec J, Streblow, Daniel N, Newman, Christina M, O’Connor, David H, Lackritz, Eve M, Van Rompay, Koen K A, Adams Waldorf, Kristina M, Adams Waldorf, Kristina M., Barrett, Alan D.T., Beasley, David W.C., Bennie, JosephY. B., Bourne, Nigel, Brault, Aaron C., Cehovin, Ana, Coelho, Christiane, Diamond, Michael S., Emperador, Devy, Faria, Nuno R., Fay, Petra C., Golding, Josephine P., Harris, Eva, Hasanin, Nagwa, Jaenisch, Thomas, Ko, Albert I., Lackritz, Eve M., Leighton, Tabitha, Leo, Yee-Sin, Mehr, Angela J., Memish, Ziad A., Méndez-Rico, Jairo A., Moore, Kristine A., Mura, Manuela, Ng, Lee-Ching, Osterholm, Michael T., Ostrowsky, Julia T., Peeling, Rosanna W., Rabe, Ingrid B., Salje, Henrik, Staples, J Erin, Thomas, Stephen J., Ulrich, Angela K., Vanhomwegen, Jessica, Wongsawat, Jurai
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.06.2025
• Subjects: Animals; Disease Models, Animal; Female; Humans; Infectious Disease; Microcephaly - virology; Pregnancy; Primates - virology; Zika Virus - pathogenicity; Zika Virus - physiology; Zika Virus Infection - epidemiology; Zika Virus Infection - prevention & control; Zika Virus Infection - virology

Zika virus, a mosquito-transmitted orthoflavivirus, has become a pathogen of global health concern ever since the virus caused an epidemic in Brazil in 2015 associated with approximately 700 000 laboratory-confirmed cases of congenital microcephaly. The subsequent spread of the epidemic in 2016 resu...