Polystyrene latex particles as indicators of abnormal plasma properties in multiple sclerosis
Polystyrene latex particles were incubated in plasma from multiple sclerosis (MS) patients or normal subjects. Compared with plasma from healthy controls, MS plasma produced a significantly lower mean electrophoretic mobility of the latex particles after the addition of linoleic acid. The effect was...
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| Published in | Neurology Vol. 34; no. 4; p. 547 |
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| Main Authors | , , |
| Format | Journal Article |
| Language | English |
| Published |
United States
01.04.1984
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| Subjects | |
| Online Access | Get more information |
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| Abstract | Polystyrene latex particles were incubated in plasma from multiple sclerosis (MS) patients or normal subjects. Compared with plasma from healthy controls, MS plasma produced a significantly lower mean electrophoretic mobility of the latex particles after the addition of linoleic acid. The effect was similar to that found when erythrocytes were used as the indicator particle. However, the result with latex particles demonstrates that the phenomenon originates from a plasma component of MS patients rather than from an intrinsic difference in membranes of the red blood cell. |
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| AbstractList | Polystyrene latex particles were incubated in plasma from multiple sclerosis (MS) patients or normal subjects. Compared with plasma from healthy controls, MS plasma produced a significantly lower mean electrophoretic mobility of the latex particles after the addition of linoleic acid. The effect was similar to that found when erythrocytes were used as the indicator particle. However, the result with latex particles demonstrates that the phenomenon originates from a plasma component of MS patients rather than from an intrinsic difference in membranes of the red blood cell. |
| Author | Seaman, G V Swank, R L Tamblyn, C H |
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| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/6538317$$D View this record in MEDLINE/PubMed |
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| Snippet | Polystyrene latex particles were incubated in plasma from multiple sclerosis (MS) patients or normal subjects. Compared with plasma from healthy controls, MS... |
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| SubjectTerms | Culture Media Electrophoresis Erythrocytes - analysis Humans Latex - analysis Multiple Sclerosis - blood Polystyrenes - analysis |
| Title | Polystyrene latex particles as indicators of abnormal plasma properties in multiple sclerosis |
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