Association of Common Genetic Variants With Contralateral Breast Cancer Risk in the WECARE Study

• Published in: JNCI : Journal of the National Cancer Institute Vol. 109; no. 10
• Main Authors: Robson, Mark E., Reiner, Anne S., Brooks, Jennifer D., Concannon, Patrick J., John, Esther M., Mellemkjaer, Lene, Bernstein, Leslie, Malone, Kathleen E., Knight, Julia A., Lynch, Charles F., Woods, Meghan, Liang, Xiaolin, Haile, Robert W., Duggan, David J., Shore, Roy E., Smith, Susan A., Thomas, Duncan C., Stram, Daniel O., Bernstein, Jonine L.
• Format: Journal Article
• Language: English
• Published: United States Oxford University Press 01.10.2017
• Subjects: Adult; Breast Neoplasms - epidemiology; Breast Neoplasms - genetics; Breast Neoplasms - pathology; Case-Control Studies; Environmental Exposure - statistics & numerical data; Female; Genetic Association Studies; Genetic Predisposition to Disease; Humans; Middle Aged; Neoplasm Recurrence, Local - epidemiology; Neoplasm Recurrence, Local - genetics; Polymorphism, Single Nucleotide; SEER Program; United States; Young Adult

Women with unilateral breast cancer (UBC) are at risk of developing a subsequent contralateral breast cancer (CBC). Common variants are associated with breast cancer risk. Whether these influence CBC risk is unknown. Participants were breast cancer cases from the population-based Women's Enviro...