The Association between Salivary Metabolites and Gingival Bleeding Score in Healthy Subjects: A Pilot Study

• Published in: International journal of molecular sciences Vol. 25; no. 10; p. 5448
• Main Authors: Antonelli, Rita, Ferrari, Elena, Gallo, Mariana, Ciociola, Tecla, Calciolari, Elena, Spisni, Alberto, Meleti, Marco, Pertinhez, Thelma A.
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 01.05.2024
• Subjects: Adult; Amino acids; Biomarkers; Biomarkers - metabolism; Classification; Enzymes; Female; Gingival Hemorrhage - metabolism; Gingivitis - diagnosis; Gingivitis - metabolism; Gum disease; Healthy Volunteers; Humans; Inflammation; Male; Metabolites; Metabolome; Metabolomics - methods; Middle Aged; Nuclear magnetic resonance spectroscopy; Pilot Projects; Saliva - metabolism; Systemic diseases; Variables; Young Adult; Taiwan; saliva; gingivitis; Full-Mouth Bleeding Score (FMBS); salivary metabolomics; salivary diagnostics
• ISSN: 1422-0067; 1661-6596; 1422-0067
• DOI: 10.3390/ijms25105448

Periodontal diseases, including gingivitis and periodontitis, are among the most prevalent diseases in humans. Gingivitis is the mildest form of periodontal disease, characterized by inflammation of the gingiva caused by the accumulation of dental plaque. Salivary diagnostics are becoming increasing...