Evaluating the Genetic Component of Ischemic Stroke Subtypes A Family History Study

• Published in: Stroke (1970) Vol. 34; no. 6; pp. 1364 - 1369
• Main Authors: Jerrard-Dunne, Paula, Cloud, Geoffrey, Hassan, Ahamad, Markus, Hugh S.
• Format: Journal Article
• Language: English
• Published: Hagerstown, MD Lippincott Williams & Wilkins 01.06.2003
• Subjects: Aged; Biological and medical sciences; Brain Ischemia - classification; Brain Ischemia - epidemiology; Brain Ischemia - genetics; Case-Control Studies; European Continental Ancestry Group - genetics; Family; Female; Gene Frequency; Humans; Ischemic Attack, Transient - epidemiology; Ischemic Attack, Transient - genetics; London - epidemiology; Male; Medical sciences; Middle Aged; Multivariate Analysis; Neurology; Odds Ratio; Risk; Risk Factors; Sample Size; Stroke - classification; Stroke - epidemiology; Stroke - genetics; Vascular Diseases - epidemiology; Vascular Diseases - genetics; Vascular diseases and vascular malformations of the nervous system; London; Human; stroke classification; Nervous system diseases; risk factors; Family study; Cardiovascular disease; Case control study; Epidemiology; Cerebral disorder; Vascular disease; Phenotype; genetics; Ischemia; cerebral infarction; Central nervous system disease; Classification; Risk factor; Cerebrovascular disease; Brain (vertebrata)

Background and Purpose— Twin and family history studies support a role for genetic factors in stroke risk. Because the etiology of ischemic stroke is heterogeneous, genetic factors may vary by etiologic subtype. We determined the familial aggregation of stroke risk in different stroke phenotypes and...