Fluoxetine treatment of alcoholic perpetrators of domestic violence: a 12-week, double-blind, randomized, placebo-controlled intervention study

• Published in: The journal of clinical psychiatry Vol. 72; no. 1; p. 60
• Main Authors: George, David T, Phillips, Monte J, Lifshitz, Mariel, Lionetti, Thomas A, Spero, David E, Ghassemzedeh, Niloofar, Doty, Linda, Umhau, John C, Rawlings, Robert R
• Format: Journal Article
• Language: English
• Published: United States 01.01.2011
• Subjects: Aggression - drug effects; Aggression - psychology; Alcoholics Anonymous; Alcoholism - psychology; Alcoholism - therapy; Anger - drug effects; Cognitive Behavioral Therapy - methods; Combined Modality Therapy; Disruptive, Impulse Control, and Conduct Disorders - drug therapy; Disruptive, Impulse Control, and Conduct Disorders - psychology; Domestic Violence - prevention & control; Domestic Violence - psychology; Double-Blind Method; Drug Administration Schedule; Female; Fluoxetine - therapeutic use; Humans; Intention to Treat Analysis; Irritable Mood - drug effects; Male; Placebos; Selective Serotonin Reuptake Inhibitors - therapeutic use; Spouse Abuse - prevention & control; Spouse Abuse - psychology; Spouses - psychology; Treatment Outcome

Behaviorally based therapies for the treatment of perpetrators who initiate intimate partner violence (IPV) have generally shown minimal therapeutic efficacy. To explore a new treatment approach for IPV, we examined the effects of a selective serotonin reuptake inhibitor on the irritability subscale...