Distinct immune signatures discriminate between asymptomatic and presymptomatic SARS-CoV-2pos subjects

• Published in: Cell research Vol. 31; no. 11; pp. 1148 - 1162
• Main Authors: Yu, Shanhe, Di, Caixia, Chen, Shijun, Guo, Mingquan, Yan, Jiayang, Zhu, Zhaoqin, Liu, Li, Feng, Ruixue, Xie, Yinyin, Zhang, Ruihong, Chen, Juan, Wang, Mengxi, Wei, Dong, Fang, Hai, Yin, Tong, Huang, Jinyan, Chen, Saijuan, Lu, Hongzhou, Zhu, Jiang, Qu, Jieming
• Format: Journal Article
• Language: English
• Published: Singapore Springer Singapore 01.11.2021; Nature Publishing Group
• Subjects: 13/1; 13/21; 13/31; 13/95; 38/91; 631/250; 631/80/304; Asymptomatic; Biomedical and Life Sciences; CD4 antigen; CD8 antigen; Cell Biology; COVID-19; Immunology; Immunosuppression; Life Sciences; Lymphocytes; Lymphocytes T; Monocytes; Natural killer cells; Severe acute respiratory syndrome coronavirus 2; Viral diseases

Increasing numbers of SARS-CoV-2-positive (SARS-CoV-2 pos ) subjects are detected at silent SARS-CoV-2 infection stage (SSIS). Yet, SSIS represents a poorly examined time-window wherein unknown immunity patterns may contribute to the fate determination towards persistently asymptomatic or overt dise...