Biological Roles and Mechanisms of Circular RNA in Human Cancers

• Published in: OncoTargets and therapy Vol. 13; pp. 2067 - 2092
• Main Authors: Tang, Qing, Hann, Swei Sunny
• Format: Journal Article
• Language: English
• Published: New Zealand Dove 01.01.2020
• Subjects: Review; miRNA sponge; circRNA; protein scaffolding; cancer; therapeutic target; biomarker; gene splicing and transcription

Circular RNA (circRNA) is an intriguing class of RNA with covalently closed-loop structure and is highly stable and conservative. As new members of the ncRNAs, the function, mechanism, potential diagnostic biomarker, and therapeutic target have raised increased attention. Most circRNAs are presented...