Extravascular Dermal Trypanosomes in Suspected and Confirmed Cases of gambiense Human African Trypanosomiasis

• Published in: Clinical infectious diseases Vol. 73; no. 1; pp. 12 - 20
• Main Authors: Camara, Mariame, Soumah, Alseny M’mah, Ilboudo, Hamidou, Travaillé, Christelle, Clucas, Caroline, Cooper, Anneli, Kuispond Swar, Nono-Raymond, Camara, Oumou, Sadissou, Ibrahim, Calvo Alvarez, Estefania, Crouzols, Aline, Bart, Jean-Mathieu, Jamonneau, Vincent, Camara, Mamadou, MacLeod, Annette, Bucheton, Bruno, Rotureau, Brice
• Format: Journal Article
• Language: English
• Published: United States Oxford University Press 01.07.2021
• Subjects: Animals; Guinea; Humans; Major and Commentaries; Prospective Studies; Trypanosoma brucei gambiense; Trypanosomiasis, African - diagnosis; Trypanosomiasis, African - epidemiology; Guinea; skin; human African trypanosomiasis; reservoir; Trypanosoma brucei gambiense

The diagnosis of gambiense human African trypanosomiasis (gHAT) typically involves 2 steps: a serological screen, followed by the detection of living trypanosome parasites in the blood or lymph node aspirate. Live parasites can, however, remain undetected in some seropositive individuals, who, we hy...