Hormone, Targeted, and Combinational Therapies for Breast Cancers: From Humans to Dogs

• Published in: International journal of molecular sciences Vol. 25; no. 2; p. 732
• Main Authors: Ke, Chiao-Hsu, Lin, Chao-Nan, Lin, Chen-Si
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 01.01.2024
• Subjects: Animals; Antibodies, Monoclonal - therapeutic use; Antimitotic agents; Antineoplastic agents; Autophagy; Biological products; Breast cancer; Breast Neoplasms - drug therapy; Canada; Cancer; Cancer therapies; Care and treatment; Clinical trials; Combined Modality Therapy; Comparative analysis; Development and progression; Dogs; Drug resistance; Endocrine therapy; Endometrial cancer; Estrogens; Female; Females; Health aspects; Hormones; Human acts; Human behavior; Humans; Kinases; Ligands; Monoclonal antibodies; Mortality; Oncology; Prospective Studies; Steroid hormones; Steroids; Taiwan; Toxicity; Tumors; Canada; Taiwan; targeted therapy; hormone therapy; canine mammary gland tumor; comparative oncology

Breast cancer (BC) is the most frequent cancer in women. In female dogs, canine mammary gland tumor (CMT) is also the leading neoplasm. Comparative oncology indicates similar tumor behaviors between human BCs (HBCs) and CMTs. Therefore, this review summarizes the current research in hormone and targ...