Circular RNAs and complex diseases: from experimental results to computational models

• Published in: Briefings in bioinformatics Vol. 22; no. 6
• Main Authors: Wang, Chun-Chun, Han, Chen-Di, Zhao, Qi, Chen, Xing
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 05.11.2021
• Subjects: Algorithms; Computational Biology - methods; Databases, Genetic; Female; Humans; Machine Learning; Models, Genetic; Neoplasms - genetics; Review; RNA, Circular - genetics; circRNA-disease association prediction; computational model; network algorithm; disease; circRNA; machine learning

Circular RNAs (circRNAs) are a class of single-stranded, covalently closed RNA molecules with a variety of biological functions. Studies have shown that circRNAs are involved in a variety of biological processes and play an important role in the development of various complex diseases, so the identi...