Effects of brodalumab on psoriasis and depressive symptoms in patients with insufficient response to TNF ‐α inhibitors
Abstract The objective of this study was to evaluate emotions of depression and anxiety in psoriatic patients that due to insufficient response to tumor necrosis factor‐alpha inhibition (TNF‐α), underwent a treatment switch from TNF‐α to interleukin 17 inhibition using brodalumab. The Self‐rated Mon...
Saved in:
Published in | Journal of dermatology Vol. 50; no. 11; pp. 1401 - 1414 |
---|---|
Main Authors | , , , , , |
Format | Journal Article |
Language | English |
Published |
Tokyo
Wiley Subscription Services, Inc
01.11.2023
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Abstract | Abstract
The objective of this study was to evaluate emotions of depression and anxiety in psoriatic patients that due to insufficient response to tumor necrosis factor‐alpha inhibition (TNF‐α), underwent a treatment switch from TNF‐α to interleukin 17 inhibition using brodalumab. The Self‐rated Montgomery‐Asberg Depression Rating Scale and the Hospital Anxiety and Depression Scale were used to assess depression and anxiety. A total of 20 patients with psoriasis were enrolled in the study. They were monitored for a period of 3 months following the transition to brodalumab treatment. The results showed a significant improvement in both the Psoriasis Area and Severity Index as well as symptoms of depression; anxiety symptoms showed a reduction, though not statistically significant. Perhaps of more interest, the positive effects on depression and anxiety seem to be independent of the reduction in skin related psoriatic lesions. These findings highlight the importance of addressing depressive and anxiety symptoms, together with psoriasis severity and quality of life, when managing patients with psoriasis. |
---|---|
AbstractList | Abstract
The objective of this study was to evaluate emotions of depression and anxiety in psoriatic patients that due to insufficient response to tumor necrosis factor‐alpha inhibition (TNF‐α), underwent a treatment switch from TNF‐α to interleukin 17 inhibition using brodalumab. The Self‐rated Montgomery‐Asberg Depression Rating Scale and the Hospital Anxiety and Depression Scale were used to assess depression and anxiety. A total of 20 patients with psoriasis were enrolled in the study. They were monitored for a period of 3 months following the transition to brodalumab treatment. The results showed a significant improvement in both the Psoriasis Area and Severity Index as well as symptoms of depression; anxiety symptoms showed a reduction, though not statistically significant. Perhaps of more interest, the positive effects on depression and anxiety seem to be independent of the reduction in skin related psoriatic lesions. These findings highlight the importance of addressing depressive and anxiety symptoms, together with psoriasis severity and quality of life, when managing patients with psoriasis. The objective of this study was to evaluate emotions of depression and anxiety in psoriatic patients that due to insufficient response to tumor necrosis factor-alpha inhibition (TNF-alpha), underwent a treatment switch from TNF-alpha to interleukin 17 inhibition using brodalumab. The Self-rated Montgomery-Asberg Depression Rating Scale and the Hospital Anxiety and Depression Scale were used to assess depression and anxiety. A total of 20 patients with psoriasis were enrolled in the study. They were monitored for a period of 3 months following the transition to brodalumab treatment. The results showed a significant improvement in both the Psoriasis Area and Severity Index as well as symptoms of depression; anxiety symptoms showed a reduction, though not statistically significant. Perhaps of more interest, the positive effects on depression and anxiety seem to be independent of the reduction in skin related psoriatic lesions. These findings highlight the importance of addressing depressive and anxiety symptoms, together with psoriasis severity and quality of life, when managing patients with psoriasis. The objective of this study was to evaluate emotions of depression and anxiety in psoriatic patients that due to insufficient response to tumor necrosis factor‐alpha inhibition (TNF‐α), underwent a treatment switch from TNF‐α to interleukin 17 inhibition using brodalumab. The Self‐rated Montgomery‐Asberg Depression Rating Scale and the Hospital Anxiety and Depression Scale were used to assess depression and anxiety. A total of 20 patients with psoriasis were enrolled in the study. They were monitored for a period of 3 months following the transition to brodalumab treatment. The results showed a significant improvement in both the Psoriasis Area and Severity Index as well as symptoms of depression; anxiety symptoms showed a reduction, though not statistically significant. Perhaps of more interest, the positive effects on depression and anxiety seem to be independent of the reduction in skin related psoriatic lesions. These findings highlight the importance of addressing depressive and anxiety symptoms, together with psoriasis severity and quality of life, when managing patients with psoriasis. |
Author | Micu, Emanuela Osmancevic, Amra Andersch‐Björkman, Ylva Lonne‐Rahm, Sol‐Britt Seifert, Oliver Gillstedt, Martin |
Author_xml | – sequence: 1 givenname: Ylva orcidid: 0009-0007-3089-0920 surname: Andersch‐Björkman fullname: Andersch‐Björkman, Ylva organization: Department of Dermatology and Venereology, Institute of Clinical Sciences, Sahlgrenska Academy University of Gothenburg Gothenburg Sweden, Department of Dermatology and Venereology, Region Västra Götaland Sahlgrenska University Hospital Gothenburg Sweden – sequence: 2 givenname: Emanuela surname: Micu fullname: Micu, Emanuela organization: Department of Dermatology and Venereology in Östergötland Vrinnevihospital Norrköping Sweden – sequence: 3 givenname: Oliver orcidid: 0000-0002-2045-7142 surname: Seifert fullname: Seifert, Oliver organization: Division of Cell Biology, Department of Biomedical and Clinical Sciences, The Faculty of Medicine and Health Sciences Linköping University Linköping Sweden – sequence: 4 givenname: Sol‐Britt surname: Lonne‐Rahm fullname: Lonne‐Rahm, Sol‐Britt organization: Division of Dermatology Mälarsjukhuset Eskilstuna Sweden – sequence: 5 givenname: Martin surname: Gillstedt fullname: Gillstedt, Martin organization: Department of Dermatology and Venereology, Institute of Clinical Sciences, Sahlgrenska Academy University of Gothenburg Gothenburg Sweden, Department of Dermatology and Venereology, Region Västra Götaland Sahlgrenska University Hospital Gothenburg Sweden – sequence: 6 givenname: Amra surname: Osmancevic fullname: Osmancevic, Amra organization: Department of Dermatology and Venereology, Institute of Clinical Sciences, Sahlgrenska Academy University of Gothenburg Gothenburg Sweden, Department of Dermatology and Venereology, Region Västra Götaland Sahlgrenska University Hospital Gothenburg Sweden |
BackLink | https://gup.ub.gu.se/publication/331316$$DView record from Swedish Publication Index |
BookMark | eNpd0U9O3DAUBnCrAolhYM3WUjfdBPw34ywRgrYSajewthznmfFoEge_pGh2PUKv0ov0ED1JPUzFAm8sffrZek_fKTka0gCEXHB2ycu54lLVleHSXPK64asPZPGWHJEFk0ZXQrHVCTlF3DAmGs3ZguxuQwA_IU2Btjl1bjv3rqVpoCOmHB1GpG7oaAdjBsT4Ayju-nFKPdJYkJsiDOX5S5zWJcA5hOj3ES18TAMCnRJ9-HZH__789ed3IevYxillPCPHwW0Rzv_fS_J4d_tw86W6__756831feWl4VOlfLfiTQABHEzrhPC6CV0QoGumVk1bhyYI5aDVKgRjWu-F9wqC8toELb1ckurwL77AOLd2zLF3eWeTi_ZpHm2JnmaLYKXkktfFfzr4MafnGXCyfUQP260bIM1ohdFNzYQUrNCP7-gmzXko2xRltCojNrKoq4PyOSFmCG8jcGb31dl9UXZflH2tTv4D5SWSEw |
CitedBy_id | crossref_primary_10_1038_s41598_024_66131_9 crossref_primary_10_1080_17512433_2024_2340552 |
Cites_doi | 10.1046/j.1468-3083.2002.00467.x 10.1111/j.1365-2230.1994.tb01167.x 10.1177/2040622317738910 10.12740/PP/68848 10.1159/000509732 10.1007/s00520-008-0543-9 10.1007/s40257-017-0254-4 10.4103/ijo.IJO_436_17 10.1111/jdv.12909 10.3390/ijms20061475 10.1016/j.jaad.2018.11.058 10.1001/archdermatol.2010.186 10.1016/S0022-3999(96)00216-4 10.1016/j.psychres.2010.10.029 10.1111/jdv.12138 10.1016/j.neuroscience.2005.03.051 10.1016/j.genhosppsych.2006.12.004 10.1016/j.jaad.2013.12.018 10.4049/jimmunol.1301737 10.3899/jrheum.110903 10.1017/S1461145702003097 10.1186/1471-244X-9-26 10.1016/j.bbi.2018.11.015 10.1111/j.1440-0960.2004.00078.x 10.1177/1359105311423863 10.1016/j.it.2005.11.006 10.2340/00015555-3712 10.3897/folmed.62.e39402 10.1016/j.biopsych.2009.09.033 10.1046/j.1365-2133.2000.03829.x 10.1192/bjp.134.4.382 10.2340/00015555-1975 10.3389/fimmu.2021.699848 10.1007/s13555-023-00909-z 10.1016/j.jad.2009.06.037 10.1001/jama.2020.4006 10.1080/08039488.2020.1733077 10.1016/j.jaad.2004.04.012 10.1016/j.jaad.2013.09.030 |
ContentType | Journal Article |
Copyright | 2023. This article is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. |
Copyright_xml | – notice: 2023. This article is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. |
DBID | AAYXX CITATION 7T5 H94 K9. 7X8 ADTPV AOWAS F1U |
DOI | 10.1111/1346-8138.16917 |
DatabaseName | CrossRef Immunology Abstracts AIDS and Cancer Research Abstracts ProQuest Health & Medical Complete (Alumni) MEDLINE - Academic SwePub SwePub Articles SWEPUB Göteborgs universitet |
DatabaseTitle | CrossRef AIDS and Cancer Research Abstracts ProQuest Health & Medical Complete (Alumni) Immunology Abstracts MEDLINE - Academic |
DatabaseTitleList | CrossRef AIDS and Cancer Research Abstracts MEDLINE - Academic |
DeliveryMethod | fulltext_linktorsrc |
Discipline | Medicine |
EISSN | 1346-8138 |
EndPage | 1414 |
ExternalDocumentID | oai_gup_ub_gu_se_331316 10_1111_1346_8138_16917 |
GroupedDBID | --- .3N .55 .GA .Y3 05W 0R~ 10A 123 1OB 1OC 29K 31~ 33P 36B 3O- 3SF 4.4 50Y 50Z 51W 51X 52M 52N 52O 52P 52R 52S 52T 52U 52V 52W 52X 53G 5HH 5LA 5RE 5VS 66C 702 7PT 8-0 8-1 8-3 8-4 8-5 8UM 930 A01 A03 AAESR AAEVG AAHHS AANLZ AAONW AAQQT AASGY AAXRX AAYXX AAZKR ABCQN ABCUV ABEML ABJNI ABPVW ABQWH ABXGK ACAHQ ACBWZ ACCFJ ACCZN ACGFS ACGOF ACMXC ACPOU ACPRK ACSCC ACXBN ACXQS ADBBV ADBTR ADEOM ADIZJ ADKYN ADMGS ADOZA ADXAS ADZMN AEEZP AEIGN AEIMD AENEX AEQDE AEUQT AEUYR AFBPY AFFNX AFFPM AFGKR AFPWT AFZJQ AHBTC AHMBA AIACR AITYG AIURR AIWBW AJBDE ALAGY ALMA_UNASSIGNED_HOLDINGS ALUQN AMBMR AMYDB ASPBG ATUGU AVWKF AZBYB AZFZN AZVAB B.R BAFTC BDRZF BFHJK BHBCM BMXJE BROTX BRXPI BY8 C45 CAG CITATION COF CS3 CYRXZ D-6 D-7 D-E D-F D-I DCZOG DPXWK DR2 DRFUL DRMAN DRSTM DU5 EBS EJD EMB EMOBN EX3 F00 F01 F04 F5P FEDTE FUBAC G-S G.N GODZA H.X HF~ HGLYW HVGLF HZI HZ~ IX1 J0M K48 KBYEO LATKE LC2 LC3 LEEKS LH4 LITHE LOXES LP6 LP7 LUTES LW6 LYRES MEWTI MK4 MRFUL MRMAN MRSTM MSFUL MSMAN MSSTM MXFUL MXMAN MXSTM N04 N05 N9A NF~ O66 O9- OIG OVD P2W P2X P2Z P4B P4D PALCI PQQKQ Q.N Q11 QB0 R.K RIWAO ROL RX1 SAMSI SJN SUPJJ SV3 TEORI UB1 W8V W99 WBKPD WHWMO WIH WIJ WIK WOHZO WOW WQJ WRC WVDHM WXI WXSBR X7M XG1 ZZTAW ~IA ~WT 7T5 H94 K9. 7X8 ADTPV AOWAS F1U |
ID | FETCH-LOGICAL-c381t-4cd719fe2e1e8ba22c59fdf2e560479b6f9f24aeb54ff88bcc2cc4ef4c58f53c3 |
ISSN | 0385-2407 |
IngestDate | Sat Aug 24 00:43:05 EDT 2024 Sat Aug 17 01:47:41 EDT 2024 Thu Oct 10 20:11:23 EDT 2024 Fri Aug 23 01:31:55 EDT 2024 |
IsDoiOpenAccess | false |
IsOpenAccess | true |
IsPeerReviewed | true |
IsScholarly | true |
Issue | 11 |
Language | English |
LinkModel | OpenURL |
MergedId | FETCHMERGED-LOGICAL-c381t-4cd719fe2e1e8ba22c59fdf2e560479b6f9f24aeb54ff88bcc2cc4ef4c58f53c3 |
Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ORCID | 0009-0007-3089-0920 0000-0002-2045-7142 |
OpenAccessLink | https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/1346-8138.16917 |
PQID | 2885456093 |
PQPubID | 1006353 |
PageCount | 14 |
ParticipantIDs | swepub_primary_oai_gup_ub_gu_se_331316 proquest_miscellaneous_2859602320 proquest_journals_2885456093 crossref_primary_10_1111_1346_8138_16917 |
PublicationCentury | 2000 |
PublicationDate | 2023-11-01 |
PublicationDateYYYYMMDD | 2023-11-01 |
PublicationDate_xml | – month: 11 year: 2023 text: 2023-11-01 day: 01 |
PublicationDecade | 2020 |
PublicationPlace | Tokyo |
PublicationPlace_xml | – name: Tokyo |
PublicationTitle | Journal of dermatology |
PublicationYear | 2023 |
Publisher | Wiley Subscription Services, Inc |
Publisher_xml | – name: Wiley Subscription Services, Inc |
References | e_1_2_9_30_1 e_1_2_9_31_1 Davami M (e_1_2_9_26_1) 2016; 7 e_1_2_9_11_1 e_1_2_9_34_1 e_1_2_9_10_1 e_1_2_9_35_1 e_1_2_9_13_1 e_1_2_9_32_1 e_1_2_9_12_1 e_1_2_9_33_1 Rivera‐Oyola R (e_1_2_9_40_1) 2020; 13 e_1_2_9_15_1 e_1_2_9_38_1 e_1_2_9_14_1 e_1_2_9_39_1 e_1_2_9_17_1 e_1_2_9_36_1 e_1_2_9_16_1 e_1_2_9_37_1 e_1_2_9_19_1 e_1_2_9_18_1 e_1_2_9_41_1 e_1_2_9_42_1 e_1_2_9_20_1 e_1_2_9_22_1 e_1_2_9_21_1 e_1_2_9_24_1 e_1_2_9_43_1 e_1_2_9_23_1 e_1_2_9_8_1 e_1_2_9_7_1 e_1_2_9_6_1 e_1_2_9_5_1 e_1_2_9_4_1 e_1_2_9_3_1 e_1_2_9_2_1 e_1_2_9_9_1 e_1_2_9_25_1 e_1_2_9_28_1 e_1_2_9_27_1 e_1_2_9_29_1 |
References_xml | – ident: e_1_2_9_5_1 doi: 10.1046/j.1468-3083.2002.00467.x – ident: e_1_2_9_14_1 doi: 10.1111/j.1365-2230.1994.tb01167.x – ident: e_1_2_9_17_1 doi: 10.1177/2040622317738910 – ident: e_1_2_9_10_1 doi: 10.12740/PP/68848 – ident: e_1_2_9_9_1 doi: 10.1159/000509732 – ident: e_1_2_9_34_1 doi: 10.1007/s00520-008-0543-9 – ident: e_1_2_9_18_1 doi: 10.1007/s40257-017-0254-4 – ident: e_1_2_9_35_1 doi: 10.4103/ijo.IJO_436_17 – volume: 13 start-page: 44 year: 2020 ident: e_1_2_9_40_1 article-title: The use of Brodalumab in three patients with psoriasis and psychiatric comorbidities publication-title: J Clin Aesthet Dermatol contributor: fullname: Rivera‐Oyola R – ident: e_1_2_9_24_1 doi: 10.1111/jdv.12909 – ident: e_1_2_9_2_1 doi: 10.3390/ijms20061475 – ident: e_1_2_9_3_1 doi: 10.1016/j.jaad.2018.11.058 – ident: e_1_2_9_8_1 doi: 10.1001/archdermatol.2010.186 – ident: e_1_2_9_29_1 doi: 10.1016/S0022-3999(96)00216-4 – volume: 7 start-page: 137 year: 2016 ident: e_1_2_9_26_1 article-title: Elevated IL‐17 and TGF‐beta serum levels: a positive correlation between T‐helper 17 cell‐related pro‐Infammatory responses with major depressive disorder publication-title: Basic Clin Neurosci contributor: fullname: Davami M – ident: e_1_2_9_27_1 doi: 10.1016/j.psychres.2010.10.029 – ident: e_1_2_9_37_1 doi: 10.1111/jdv.12138 – ident: e_1_2_9_22_1 doi: 10.1016/j.neuroscience.2005.03.051 – ident: e_1_2_9_7_1 doi: 10.1016/j.genhosppsych.2006.12.004 – ident: e_1_2_9_31_1 doi: 10.1016/j.jaad.2013.12.018 – ident: e_1_2_9_16_1 doi: 10.4049/jimmunol.1301737 – ident: e_1_2_9_20_1 doi: 10.3899/jrheum.110903 – ident: e_1_2_9_21_1 doi: 10.1017/S1461145702003097 – ident: e_1_2_9_30_1 doi: 10.1186/1471-244X-9-26 – ident: e_1_2_9_25_1 doi: 10.1016/j.bbi.2018.11.015 – ident: e_1_2_9_4_1 doi: 10.1111/j.1440-0960.2004.00078.x – ident: e_1_2_9_6_1 doi: 10.1177/1359105311423863 – ident: e_1_2_9_19_1 doi: 10.1016/j.it.2005.11.006 – ident: e_1_2_9_39_1 doi: 10.2340/00015555-3712 – ident: e_1_2_9_15_1 doi: 10.3897/folmed.62.e39402 – ident: e_1_2_9_23_1 doi: 10.1016/j.biopsych.2009.09.033 – ident: e_1_2_9_41_1 doi: 10.1046/j.1365-2133.2000.03829.x – ident: e_1_2_9_32_1 doi: 10.1192/bjp.134.4.382 – ident: e_1_2_9_12_1 – ident: e_1_2_9_43_1 doi: 10.2340/00015555-1975 – ident: e_1_2_9_38_1 doi: 10.3389/fimmu.2021.699848 – ident: e_1_2_9_36_1 doi: 10.1007/s13555-023-00909-z – ident: e_1_2_9_28_1 doi: 10.1016/j.jad.2009.06.037 – ident: e_1_2_9_11_1 doi: 10.1001/jama.2020.4006 – ident: e_1_2_9_33_1 doi: 10.1080/08039488.2020.1733077 – ident: e_1_2_9_13_1 doi: 10.1016/j.jaad.2004.04.012 – ident: e_1_2_9_42_1 doi: 10.1016/j.jaad.2013.09.030 |
SSID | ssj0029510 |
Score | 2.4161942 |
Snippet | Abstract
The objective of this study was to evaluate emotions of depression and anxiety in psoriatic patients that due to insufficient response to tumor... The objective of this study was to evaluate emotions of depression and anxiety in psoriatic patients that due to insufficient response to tumor necrosis... |
SourceID | swepub proquest crossref |
SourceType | Open Access Repository Aggregation Database |
StartPage | 1401 |
SubjectTerms | Anxiety brodalumab depression Dermatologi och venereologi Dermatology and Venereal Diseases IL-17 inhibitor Interleukin 17 Mental depression Monoclonal antibodies Patients Psoriasis Quality of life Skin diseases Statistical analysis Tumor necrosis factor Tumor necrosis factor-TNF |
Title | Effects of brodalumab on psoriasis and depressive symptoms in patients with insufficient response to TNF ‐α inhibitors |
URI | https://www.proquest.com/docview/2885456093 https://search.proquest.com/docview/2859602320 https://gup.ub.gu.se/publication/331316 |
Volume | 50 |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1tb9MwELbKkBBfEK-iMJCRGEKaUjW28_ZxHZ0mRIc0Oml8imzXWQssqdqkAv4Vf4TfxF3ivBQxNPjiRq4VR77H57vz4zMhL_XMuGAlSyeQHKNVAXOiCLwUPfQ85jPlJ2UC08mJf3wm3p57573e1w5rqcjVQH__47mS_5Eq1IFc8ZTsP0i2eSlUwDPIF0qQMJTXkvG4JWMoUIQSFI1UGP5frjPoHnONYFy8ZrtuzP762-Uyzy4r8niVUtWeb0NSeplOAskBq4o5W16rMT05cvYOx3sjF9rMF2qB9_NcYdPOUM_nW5H6g_L0jJ47o0-4KT_yV59t0PXjl02zJkwWuijV8qAJ-Rgk3ZRLxPum8h3ScpxTOS9R_GGwPxp0wxaM2_N7rXbjoYdbO0FXFVc5aGvIuR3Fin7gXzS-y4XvhC4PB5j8J2gXt6002hfFMi4U_MRrE3Pucte_QW6yIPKQDPrmtEk8xtDuLPef7EfapFDIAfutq217puOkdBPPlsbK9C65YyVCDyrI3CM9k94ntyaWR_GAbCxyaJbQFjk0S2mDHArIoS1yaI0cuoBGFjkUkUO7yKE1cmieUUTOzx-0Rc1DcnY0nh4eO_YGDkeDJZc7Qs8CN0oMM64JlWRMe1EyS5gBO1kEEczkKGFCGuWJJAlDpTXTWphEaC-ESa75I7KTZql5TKiJZKiGJmBaKSEklMgekHwoXDmDVaFPXtfjGC-rRCtx7aDikMc45HE55H2yW49zbGfjOmZhiM7AMOJ98qL5G3QlboDJ1GQFtvHAYQcfYtgnryr5NH1dgY8n1234lNxuYb5LdvJVYZ6BvZqr5yW0fgGATptN |
link.rule.ids | 230,315,786,790,891,27955,27956 |
linkProvider | Wiley-Blackwell |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Effects+of+brodalumab+on+psoriasis+and+depressive+symptoms+in+patients+with+insufficient+response+to+TNF-%CE%B1+inhibitors&rft.jtitle=Journal+of+dermatology&rft.au=Andersch-Bj%C3%B6rkman%2C+Ylva&rft.au=Micu%2C+E.&rft.au=Seifert%2C+O.&rft.au=Lonne-Rahm%2C+S.+B.&rft.date=2023-11-01&rft.issn=0385-2407&rft.volume=50&rft.issue=11&rft.spage=1401&rft_id=info:doi/10.1111%2F1346-8138.16917&rft.externalDocID=oai_gup_ub_gu_se_331316 |
thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0385-2407&client=summon |
thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0385-2407&client=summon |
thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0385-2407&client=summon |