Schisandrin B inhibits α-melanocyte-stimulating hormone-induced melanogenesis in B16F10 cells via downregulation of MAPK and CREB signaling pathways

• Published in: Bioscience, biotechnology, and biochemistry Vol. 85; no. 4; pp. 834 - 841
• Main Authors: Zhao, Na, Su, Xiaoming, Li, He, Li, Zhengyi, Wang, Yueyang, Chen, Jianguang, Zhuang, Wenyue
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 24.03.2021
• Subjects: MAPK pathway; melanogenesis; skin whitening; schisandrin B

ABSTRACT Schisandrin B (Sch B), a lignan compound in Schisandra, possesses antioxidant, anti-inflammatory, and antiobesity activities. The effect of Sch B on melanogenesis and molecular mechanisms are still unknown. Therefore, we aimed to investigate the antimelanogenic effects of Sch B on α-melanoc...