Effect of Hemodilution In Vitro with Hydroxyethyl Starch on Hemostasis

• Published in: Medical science monitor Vol. 23; pp. 2189 - 2197
• Main Authors: Jin, Shanliang, Yu, Guifang, Hou, Ruijiao, Shen, Boxiong, Jiang, Hong
• Format: Journal Article
• Language: English
• Published: United States International Scientific Literature, Inc 08.05.2017
• Subjects: Adult; Blood Coagulation - drug effects; Blood Platelets - metabolism; Calibration; Fibrinolysis - drug effects; Flow Cytometry; Hemodilution; Hemostasis - drug effects; Humans; Hydroxyethyl Starch Derivatives - pharmacology; Isotonic Solutions - pharmacology; Lab/In Vitro Research; Middle Aged; Ringer's Lactate; Thrombin - pharmacology

BACKGROUND Hydroxyethyl starch (HES) solutions are used for volume expansion during surgery. We aimed to investigate how 6%HES 130/0.4 affects hemostasis. MATERIAL AND METHODS Blood samples were collected from 12 healthy adult volunteers, diluting with 6%HES 130/0.4 (HES group) or Ringer lactate sol...