Downregulation of MiR-199b-5p Inducing Differentiation of Bone-Marrow Mesenchymal Stem Cells (BMSCs) Toward Cardiomyocyte-Like Cells via HSF1/HSP70 Pathway

BACKGROUND Bone-marrow mesenchymal stem cells (BMSCs) are pluripotent stem cells with potent self-renewal and differentiation ability that are widely used in transplantation of cell therapy. But the mechanism on microRNA (miRNA) regulating stem cell differentiation is complicated and unclear. The ai...

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Bibliographic Details
Published inMedical science monitor Vol. 24; pp. 2700 - 2710
Main Authors Dai, Fangjie, Du, Peizhao, Chang, Yaowei, Ji, Endong, Xu, Yunjia, Wei, Chunyan, Li, Jiming
Format Journal Article
LanguageEnglish
Published United States International Scientific Literature, Inc 01.05.2018
Subjects
Clinical Research
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