Extracardiac pressure changes do not alter contractile function of the isolated left ventricle

• Published in: Annals of biomedical engineering Vol. 15; no. 3-4; p. 347
• Main Authors: Midei, M G, Maughan, W L, Oikawa, R Y, Kass, D A, Sagawa, K
• Format: Journal Article
• Language: English
• Published: United States 01.01.1987
• Subjects: Animals; Dogs; Heart Ventricles; In Vitro Techniques; Myocardial Contraction; Physiology - instrumentation; Pressure; Thorax - physiology

To determine whether or not extracardiac pressure has an effect on left ventricular contractile function, we analyzed pressure-volume relationships of six isolated, perfused canine hearts in an air-tight chamber. The chamber pressure was set at -60, -30, 0, 30 and 60 mm Hg and left ventricular press...