miR-182-5p improves the viability, mitosis, migration, and invasion ability of human gastric cancer cells by down-regulating RAB27A

• Published in: Bioscience reports Vol. 37; no. 3
• Main Authors: Li, Yuling, Chen, Shudong, Shan, Zhengfei, Bi, Liyan, Yu, Shengqiang, Li, Yongwei, Xu, Sen
• Format: Journal Article
• Language: English
• Published: England Portland Press Ltd 30.06.2017
• Subjects: Cell Line, Tumor; Cell Movement; Cell Survival; Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; MicroRNAs - genetics; Mitosis; Neoplasm Invasiveness - genetics; Neoplasm Invasiveness - pathology; rab27 GTP-Binding Proteins - genetics; Stomach Neoplasms - genetics; Stomach Neoplasms - pathology; gastric cancer; RAB27A; miR-182-5p

We investigated the effect of miR-182-5p on the viability, proliferation, invasion, and migration ability of human gastric cells by regulating the expression of RAB27A. Real-time PCR assay was used to detect the expression of miR-182-5 and RAB27A in human gastric carcinoma tissues, para-carcinoma ti...