Accurate volume image reconstruction for digital breast tomosynthesis with directional-gradient and pixel sparsity regularization

• Published in: Journal of medical imaging (Bellingham, Wash.) Vol. 12; no. S1; p. S13013
• Main Authors: Sidky, Emil Y., Wu, Xiangyi, Duan, Xiaoyu, Huang, Hailiang, Zhao, Wei, Zhang, Leo Y., Phillips, John Paul, Zhang, Zheng, Chen, Buxin, Xia, Dan, Reiser, Ingrid S., Pan, Xiaochuan
• Format: Journal Article
• Language: English
• Published: United States Society of Photo-Optical Instrumentation Engineers 01.01.2025; SPIE
• Subjects: Adjuvant treatment; Cancer; Peru; digital breast tomosynthesis; sparsity regularization; image reconstruction; dual-energy X-ray tomography

We aim to develop accurate volumetric quantitative imaging of iodinated contrast agent (ICA) in contrast-enhanced digital breast tomosynthesis (DBT). The two main components of the approach are the use of a dual-energy DBT (DE-DBT) scan and the development of an optimization-based algorithm that can...