Letter to the Editor: Human Pluripotent Stem Cells Release Oncogenic Soluble E‐Cadherin

• Published in: Stem cells (Dayton, Ohio) Vol. 34; no. 9; pp. 2443 - 2446
• Main Authors: Rosner, Margit, Hengstschläger, Markus
• Format: Journal Article
• Language: English
• Published: United States Oxford University Press 01.09.2016
• Subjects: Cadherins - secretion; Cell adhesion; Crosstalk; Editors; Embryo cells; Human pluripotent stem cells; Humans; Intracellular signalling; Matrix metalloproteinase; Matrix Metalloproteinases - metabolism; Metalloproteinase; Oncogenes; Oncogenic soluble E‐cadherin; Paracrine signaling; Paracrine signalling; Pluripotency; Pluripotent Stem Cells - secretion; Regenerative medicine; Shedding; Solubility; Stem cells; Stem cell‐based therapy; Oncogenic soluble E-cadherin; Paracrine signaling; Human pluripotent stem cells; Stem cell-based therapy

Since their discovery, human pluripotent stem cells (hPSCs) including embryonic and induced pluripotent stem cells hold great promise in disease modeling and regenerative medicine. Despite intensive research and remarkable progress, it is becoming increasingly acknowledged that their yet incomplete,...