Amino Assets: How Amino Acids Support Immunity

• Published in: Cell metabolism Vol. 32; no. 2; pp. 154 - 175
• Main Authors: Kelly, Beth, Pearce, Erika L.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 04.08.2020
• Subjects: amino acids; immunometabolism; lymphocytes; macrophages; metabolic pathways; T cells; macrophages; lymphocytes; T cells; immunometabolism; metabolic pathways; amino acids

Amino acids are fundamental building blocks supporting life. Their role in protein synthesis is well defined, but they contribute to a host of other intracellular metabolic pathways, including ATP generation, nucleotide synthesis, and redox balance, to support cellular and organismal function. Immun...