Effect of Uremia and Dialysis Modality on Mononuclear Cell Apoptosis

• Published in: Journal of the American Society of Nephrology Vol. 11; no. 5; pp. 936 - 942
• Main Authors: MARTÍN-MALO, ALEJANDRO, CARRACEDO, JULIA, RAMÍREZ, RAFAEL, RODRIGUEZ-BENOT, ALBERTO, SORIANO, SAGRARIO, RODRIGUEZ, MARIANO, ALJAMA, PEDRO
• Format: Journal Article
• Language: English
• Published: Hagerstown, MD Lippincott Williams & Wilkins 01.05.2000
• Subjects: Adult; Aged; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy; Apoptosis; Biological and medical sciences; Cells, Cultured; Cross-Sectional Studies; Emergency and intensive care: renal failure. Dialysis management; Erythropoietin - administration & dosage; Female; Humans; Intensive care medicine; Kidney Failure, Chronic - therapy; Leukocytes, Mononuclear - pathology; Male; Medical sciences; Membranes, Artificial; Middle Aged; Peritoneal Dialysis, Continuous Ambulatory - adverse effects; Peritoneal Dialysis, Continuous Ambulatory - instrumentation; Renal Dialysis - adverse effects; Renal Dialysis - instrumentation; Statistics, Nonparametric; Uremia - blood; Uremia - therapy; Kidney disease; Human; Extrarenal dialysis; Urinary system disease; Mononuclear cell; Treatment; Pathophysiology; Hemodialysis; Renal failure; Uremia; Apoptosis

The aim of this study was to evaluate the effect of both uremia itself and hemodialysis (HD) membranes on the induction of apoptosis. Four groups of subjects were evaluated: 21 nondialyzed (Non-D) patients, 10 continuous ambulatory peritoneal dialysis (CAPD) patients, and 53 HD patients who were on...