Vitamin D receptor gene polymorphism is associated with chronic periodontitis

• Published in: Life sciences (1973) Vol. 73; no. 26; pp. 3313 - 3321
• Main Authors: Tachi, Yoichi, Shimpuku, Hitomi, Nosaka, Yasuhiro, Kawamura, Tatsuya, Shinohara, Mitsuko, Ueda, Masatoshi, Imai, Hisao, Ohura, Kiyoshi
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Inc 14.11.2003
• Subjects: Adult; Aged; Case-Control Studies; Case-control study; Chronic Disease; Chronic periodontitis; Deoxyribonucleases, Type II Site-Specific; DNA - analysis; Female; Gene; Genetic Predisposition to Disease; Genotype; Hepatitis B virus; Humans; Japan - epidemiology; Male; Middle Aged; Mycobacterium; Odds Ratio; Periodontitis - epidemiology; Periodontitis - genetics; Periodontitis - pathology; Polymerase Chain Reaction; Polymorphism; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Receptors, Calcitriol - genetics; Taq Polymerase - genetics; Taq Polymerase - metabolism; Vitamin D receptor; Japan; Case-control study; Chronic periodontitis; Gene; Vitamin D receptor; Polymorphism

Chronic periodontitis (CP) is caused by enhanced resorption of the alveolar bone supporting the teeth and is associated with intraoral inflammation after infection with certain bacteria. The VDR gene polymorphism was reported recently to be deeply related to the occurrence of tuberculosis and infect...