Studies on polyamine biosynthesis in Euglena gracilis

Euglene gracilis (strain Z) was found to contain five polyamines which could be separated by high-pressure cation-exchange chromatography. 1,3-Diaminopropane, putrescine, norspermidine (N-(3-aminopropyl)-1,3-diaminopropane), spermidine and norspermine (N,N'-bis(aminopropyl)-1,3-diaminopropane)...

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Bibliographic Details
Published inBiochimica et biophysica acta Vol. 565; no. 1; pp. 199 - 207
Main Authors Aleksijevic, A, Grove, J, Schuber, F
Format Journal Article
LanguageEnglish
Published Netherlands 22.11.1979
Subjects
Adenosylmethionine Decarboxylase - metabolism
Algae
Animals
Euglena gracilis - metabolism
Models, Chemical
Ornithine Decarboxylase - metabolism
Polyamines - biosynthesis
Spermidine - analogs & derivatives
Spermidine - biosynthesis
Spermine - analogs & derivatives
Spermine - biosynthesis
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Summary:Euglene gracilis (strain Z) was found to contain five polyamines which could be separated by high-pressure cation-exchange chromatography. 1,3-Diaminopropane, putrescine, norspermidine (N-(3-aminopropyl)-1,3-diaminopropane), spermidine and norspermine (N,N'-bis(aminopropyl)-1,3-diaminopropane) were identified. Biosynthesis of putrescine in E. gracilis proceeds through decarboxylation of L-ornithine, no arginine decarboxylase (EC 4.1.1.19) activity could be detected. The properties of the enzymes ornithine decarboxylase (EC 4.1.1.17) and S-adenosylmethionine decarboxylase (EC 4.1.1.50) in this alga were found to be similar to those of the enzymes isolated from animal tissues or yeast cells. A bioxynthetic scheme is proposed which relates the different polyamines occurring in E. gracilis.
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ISSN:0006-3002
1878-2434
DOI:10.1016/0005-2787(79)90096-0