Long-term pharmacokinetics of an extract of isoflavones from red clover (Trifolium pratense)

• Published in: The journal of alternative and complementary medicine (New York, N.Y.) Vol. 8; no. 2; p. 135
• Main Authors: Howes, Jan, Waring, Mark, Huang, Li, Howes, Laurence G
• Format: Journal Article
• Language: English
• Published: United States 01.04.2002
• Subjects: Adult; Chromatography, High Pressure Liquid; Dietary Supplements; Dose-Response Relationship, Drug; Female; Genistein - pharmacokinetics; Humans; Isoflavones - blood; Isoflavones - pharmacokinetics; Isoflavones - therapeutic use; Male; Middle Aged; Plant Extracts - blood; Plant Extracts - pharmacokinetics; Plant Extracts - therapeutic use; Time Factors; Trifolium

To study the pharmacokinetics of isoflavones from red clover (Trifolium pratense) after long-term administration as a once-daily dietary supplementary. Fourteen (14) subjects who had been consuming a low-isoflavone diet for 2 weeks were given an oral dose of two isoflavone tablets (approximately 80...