Effects of Lipoxin A4 Pretreatment on Cognitive Function of Aged Rats after Global Cerebral Ischemia Reperfusion

• Published in: Current medical science Vol. 38; no. 4; pp. 666 - 671
• Main Authors: Wu, Hui-sheng, Guo, Pei-pei, Jin, Zhao, Li, Xin-yi, Yang, Xin, Ke, Jan-juan, Wang, Yan-lin, Feng, Xiao-bo
• Format: Journal Article
• Language: English
• Published: Wuhan Huazhong University of Science and Technology 01.08.2018; Department of Anesthesiology, Zhongnan Hospital, Wuhan University, Wuhan 430071, China
• Subjects: Medicine; Medicine & Public Health; pretreatment;cognitive function; lipoxin; cerebral ischemia reperfusion; cognitive function; pretreatment

Summary The aim of the present study was to investigate the effect of lipoxin A4 (LXA4) pretreatment on cognitive function of aged rats after global cerebral ischemia reperfusion, and to explore its possible mechanism. Thirty-six aged male Sprague-Dawley rats were randomly divided into three groups...