Correlation between Histone Deacetylase 9 and Regulatory T Cell in Patients with Chronic Heart Failure

• Published in: Current medical science Vol. 38; no. 2; pp. 199 - 203
• Main Authors: Liao, Ping-ping, Liu, Li-hua, Wang, Bin, Fang, Xin, Zhou, Shao-qiong, Li, Wei, Zhang, Yan-qing, Guan, Si-ming
• Format: Journal Article
• Language: English
• Published: Wuhan Huazhong University of Science and Technology 01.04.2018; Department of Geriatrics, the Affiliated Hospital of Qingdao University, Qingdao 266003, China%Department of Geriatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology,Wuhan 430022, China
• Subjects: Medicine; Medicine & Public Health; regulatory T cells; heart failure; B-type natriuretic peptide; histone deacetylase 9
• ISSN: 2096-5230; 2523-899X; 1672-0733; 2523-899X
• DOI: 10.1007/s11596-018-1866-5

Summary Heart failure (HF) is the end stage of various kinds of cardiovascular diseases and leads to a high mortality worldwide. Numerous studies have demonstrated that frequencies of CD4+CD25+Foxp3+ regulatory T cells (Tregs) are reduced in HF patients and properly expanding Tregs attenuates HF pro...