A Phytophthora palmivora Extracellular Cystatin-Like Protease Inhibitor Targets Papain to Contribute to Virulence on Papaya

• Published in: Molecular plant-microbe interactions Vol. 31; no. 3; pp. 363 - 373
• Main Authors: Gumtow, Rebecca, Wu, Dongliang, Uchida, Janice, Tian, Miaoying
• Format: Journal Article
• Language: English
• Published: United States 01.03.2018
• Subjects: cystatins; enzyme activity; gene editing; homozygosity; insects; leaves; mutants; papain; papayas; pathogens; Phytophthora palmivora; stems; transcriptomics; virulence

Papaya fruits, stems, and leaves are rich in papain, a cysteine protease that has been shown to mediate plant defense against pathogens and insects. Yet the oomycete Phytophthora palmivora is a destructive pathogen that infects all parts of papaya plants, suggesting that it has evolved cysteine prot...