Association of Serotonin Receptors with Attention Deficit Hyperactivity Disorder: A Systematic Review and Meta-analysis

• Published in: Current medical science Vol. 38; no. 3; pp. 538 - 551
• Main Authors: Hou, Yu-wei, Xiong, Ping, Gu, Xue, Huang, Xin, Wang, Min, Wu, Jing
• Format: Journal Article
• Language: English
• Published: Wuhan Huazhong University of Science and Technology 01.06.2018; Key Laboratory of Environment and Health, Ministry of Education & Department of Epidemiology and Biostatistics,School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China%Department of Rehabilitation, Wuhan Children's Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430015, China
• Subjects: Attention Deficit Disorder with Hyperactivity - genetics; Genetic Association Studies; Genetic Predisposition to Disease; Humans; Medicine; Medicine & Public Health; Odds Ratio; Polymorphism, Single Nucleotide - genetics; Receptors, Serotonin - genetics; Risk Factors; meta-analysis; serotonin receptor; attention deficit hyperactivity disorder; genetic variations; association study

Summary Attention deficit hyperactivity disorder (ADHD) is one of the most common mental disorders in childhood, with a high heritability about 60% to 90%. Serotonin is a monoamine neurotransmitter. Numerous studies have reported the association between the serotonin receptor family (5-HTR) gene pol...