A high containment polymodal pilot-plant fermenter--design concepts

• Published in: Journal of chemical technology and biotechnology (1986) Vol. 50; no. 2; p. 167
• Main Authors: Hambleton, P, Griffiths, J B, Cameron, D R, Melling, J
• Format: Journal Article
• Language: English
• Published: England 1991
• Subjects: Animals; Biotechnology - instrumentation; Biotechnology - methods; Biotechnology - standards; Fermentation

A 225 dm3 pilot-plant bioreactor system has been designed and constructed that is suitable for biohazardous fermentations. The design enables operation at containment levels above the requirements of good industrial large-scale practice (GILSP) without secondary containment of the whole plant. The m...