ZNF384: A Potential Therapeutic Target for Psoriasis and Alzheimer’s Disease Through Inflammation and Metabolism

• Published in: Frontiers in immunology Vol. 13; p. 892368
• Main Authors: Liu, Shougang, Yuan, Xiuqing, Su, Hang, Liu, Fanghua, Zhuang, Zhe, Chen, Yongfeng
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 20.05.2022
• Subjects: Alzheimer Disease - genetics; Alzheimer’s disease; Computational Biology; Humans; Immunology; inflammation; Inflammation - genetics; Ligands; metabolic disorders; PPAR gamma; psoriasis; Psoriasis - genetics; Psoriasis - metabolism; Trans-Activators; transcription factors; Transcription Factors - genetics; metabolic disorders; Alzheimer’s disease; inflammation; transcription factors; psoriasis

Psoriasis is an immune-related skin disease notable for its chronic inflammation of the entire system. Alzheimer's disease (AD) is more prevalent in psoriasis than in the general population. Immune-mediated pathophysiologic processes may link these two diseases, but the mechanism is still uncle...