IFN-γ-Primed hUCMSCs Significantly Reduced Inflammation via the Foxp3/ROR-γt/STAT3 Signaling Pathway in an Animal Model of Multiple Sclerosis - Ling, Xiao; Wang, Teng; Han, Chao; Wang, Pin; Liu, Xiaoli; Zheng, Chengyun; Bi, Jianzhong; Zhou, Xiaoyan (Frontiers in immunology, 2022)
Keywords: Animals; Cytokines - metabolism; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; experimental autoimmune encephalomyelitis (EAE); Forkhead Transcription Factors - metabolism; Foxp3/ROR-γt/STAT3 signaling pathway; Humans; IFN-γ-primed human umbilical cord mesenchymal stem cell (IFN-γ-hUCMSCs); Immunology; indoleamine 2,3-dioxygenease (IDO); Inflammation; Interferon-gamma - metabolism; Mice; Mice, Inbred C57BL; multiple sclerosis (MS); Multiple Sclerosis - therapy; Nuclear Receptor Subfamily 1, Group F, Member 3 - metabolism; Signal Transduction; STAT3 Transcription Factor - metabolism; Umbilical Cord; Foxp3/ROR-γt/STAT3 signaling pathway; multiple sclerosis (MS); IFN-γ-primed human umbilical cord mesenchymal stem cell (IFN-γ-hUCMSCs); indoleamine 2,3-dioxygenease (IDO); experimental autoimmune encephalomyelitis (EAE)