Gender- and Age-Associated Differences in Bone Marrow Adipose Tissue and Bone Marrow Fat Unsaturation Throughout the Skeleton, Quantified Using Chemical Shift Encoding-Based Water–Fat MRI

• Published in: Frontiers in endocrinology (Lausanne) Vol. 13; p. 815835
• Main Authors: Beekman, Kerensa M., Regenboog, Martine, Nederveen, Aart J., Bravenboer, Nathalie, den Heijer, Martin, Bisschop, Peter H., Hollak, Carla E., Akkerman, Erik M., Maas, Mario
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 27.04.2022
• Subjects: Adipose Tissue - diagnostic imaging; Animals; Bone and Bones - diagnostic imaging; Bone Marrow - diagnostic imaging; bone marrow adipose tissue; bone marrow adipose tissue distribution; bone marrow fat unsaturation; Cross-Sectional Studies; Endocrinology; Female; healthy subjects; Humans; Lumbar Vertebrae - diagnostic imaging; Magnetic Resonance Imaging - methods; Male; Water; water–fat MR imaging; bone marrow adipose tissue distribution; healthy subjects; water–fat MR imaging; bone marrow fat unsaturation; bone marrow adipose tissue

Bone marrow adipose tissue (BMAT) is a dynamic tissue which is associated with osteoporosis, bone metastasis, and primary bone tumors. The aim of this study is to determine region-specific variations and age- and gender-specific differences in BMAT and BMAT composition in healthy subjects. In this c...