The use of regional citrate anticoagulation for continuous venovenous hemodiafiltration in acute kidney injury

• Published in: Critical care medicine Vol. 36; no. 11; p. 3024
• Main Authors: Durão, Marcelino S, Monte, Julio C M, Batista, Marcelo C, Oliveira, Moacir, Iizuka, Ilson J, Santos, Bento F, Pereira, Virgilio G, Cendoroglo, Miguel, Santos, Oscar F P
• Format: Journal Article
• Language: English
• Published: United States 01.11.2008
• Subjects: Acute Kidney Injury - blood; Acute Kidney Injury - therapy; Adolescent; Adult; Aged; Anticoagulants - administration & dosage; Anticoagulants - adverse effects; Citrates - administration & dosage; Citrates - adverse effects; Cohort Studies; Critical Care; Female; Hemodiafiltration - methods; Humans; Liver Failure - complications; Male; Middle Aged; Retrospective Studies; Sepsis - complications; Treatment Outcome

Continuous renal replacement therapy is commonly used in the treatment of acute kidney injury. Although the optimal anticoagulation system is not well defined, citrate has emerged as the most promising method. We evaluated the data of 143 patients with acute kidney injury subjected to citrate-based...