Anti-steroidogenic activity of the two Indian medicinal plants in mice
The chloroform extract of Croton roxburghii bark (CECR, Euphorbiaceae) and ethyl acetate extract of Zizyphus jujuba bark (EAZJ, Rhamnaceae) were evaluated for anti-steroidogenic activity in the adult female mouse. This study was designed to assess the effects of CECR and EAZJ on ovarian steroidogeni...
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| Published in | Journal of ethnopharmacology Vol. 90; no. 1; pp. 21 - 25 |
|---|---|
| Main Authors | , , , , |
| Format | Journal Article |
| Language | English |
| Published |
Shannon
Elsevier Ireland Ltd
2004
Elsevier |
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| Abstract | The chloroform extract of
Croton roxburghii bark (CECR, Euphorbiaceae) and ethyl acetate extract of
Zizyphus jujuba bark (EAZJ, Rhamnaceae) were evaluated for anti-steroidogenic activity in the adult female mouse. This study was designed to assess the effects of CECR and EAZJ on ovarian steroidogenisis. Antifertility activity was evaluated by observing the estrus cycle, body weight, wet weight of ovaries, steroidogenic enzymes, and substrates. Blood profiles were estimated to find out the toxic manifestations of the extracts. CECR and EAZJ each arrested the normal estrus cycle of adult female mouse at diestrus stage and reduced the wet weight of ovaries significantly. Cholesterol and ascorbic acid content in ovaries of crude extract-treated mice were significantly elevated. The significant inhibition of Δ
5-3β-hydroxysteroid dehydrogenase (Δ
5-3β-HSD) and glucose-6-phosphate dehydrogenase (G-6-PDH), the two key enzymes involved in ovarian steroidogenisis, were also observed in mouse after 18 days of treatment. Hematological profiles, biochemical estimations of whole blood and serum remains unaltered in extract-treated mouse. Normal estrus cycle and ovarian steroidogenisis were restored after withdrawal of treatment with CECR and EAZJ on average 27 and 32 days, respectively. Antifertility activities of crude extracts were found to be reversible. |
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| AbstractList | The chloroform extract of Croton roxburghii bark (CECR, Euphorbiaceae) and ethyl acetate extract of Zizyphus jujuba bark (EAZJ, Rhamnaceae) were evaluated for anti-steroidogenic activity in the adult female mouse. This study was designed to assess the effects of CECR and EAZJ on ovarian steroidogenisis. Antifertility activity was evaluated by observing the estrus cycle, body weight, wet weight of ovaries, steroidogenic enzymes, and substrates. Blood profiles were estimated to find out the toxic manifestations of the extracts. CECR and EAZJ each arrested the normal estrus cycle of adult female mouse at diestrus stage and reduced the wet weight of ovaries significantly. Cholesterol and ascorbic acid content in ovaries of crude extract-treated mice were significantly elevated. The significant inhibition of delta(5)-3beta-hydroxysteroid dehydrogenase (delta(5)-3beta-HSD) and glucose-6-phosphate dehydrogenase (G-6-PDH), the two key enzymes involved in ovarian steroidogenisis, were also observed in mouse after 18 days of treatment. Hematological profiles, biochemical estimations of whole blood and serum remains unaltered in extract-treated mouse. Normal estrus cycle and ovarian steroidogenisis were restored after withdrawal of treatment with CECR and EAZJ on average 27 and 32 days, respectively. Antifertility activities of crude extracts were found to be reversible. The chloroform extract of Croton roxburghii bark (CECR, Euphorbiaceae) and ethyl acetate extract of Zizyphus jujuba bark (EAZJ, Rhamnaceae) were evaluated for anti-steroidogenic activity in the adult female mouse. This study was designed to assess the effects of CECR and EAZJ on ovarian steroidogenisis. Antifertility activity was evaluated by observing the estrus cycle, body weight, wet weight of ovaries, steroidogenic enzymes, and substrates. Blood profiles were estimated to find out the toxic manifestations of the extracts. CECR and EAZJ each arrested the normal estrus cycle of adult female mouse at diestrus stage and reduced the wet weight of ovaries significantly. Cholesterol and ascorbic acid content in ovaries of crude extract-treated mice were significantly elevated. The significant inhibition of Δ 5-3β-hydroxysteroid dehydrogenase (Δ 5-3β-HSD) and glucose-6-phosphate dehydrogenase (G-6-PDH), the two key enzymes involved in ovarian steroidogenisis, were also observed in mouse after 18 days of treatment. Hematological profiles, biochemical estimations of whole blood and serum remains unaltered in extract-treated mouse. Normal estrus cycle and ovarian steroidogenisis were restored after withdrawal of treatment with CECR and EAZJ on average 27 and 32 days, respectively. Antifertility activities of crude extracts were found to be reversible. |
| Author | Gupta, M Vamsi, M.L.M Mazumder, U.K Sivakumar, T Kandar, C.C |
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| Cites_doi | 10.1016/0031-9422(91)85063-6 10.1210/endo-69-3-527 10.1111/j.2042-7158.1995.tb05737.x 10.1016/B978-0-12-091302-2.50026-8 10.1210/endo-78-5-976 10.1210/endo-73-5-588 10.1677/joe.0.0930415 10.3181/00379727-203-43567 10.1210/endo-74-5-814 10.1016/S0031-9422(00)83976-X 10.1016/S0021-9258(19)52451-6 10.1016/S0002-9378(84)80036-8 10.1016/S0021-9258(18)56747-8 10.1210/endo-72-5-813 10.1016/0076-6879(79)62181-X 10.1210/endo-69-3-619 |
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| Keywords | Zizyphus jujuba Hematological profiles Biomarker enzymes Croton roxburghii Antifertility Enzyme Pharmacognosy Rodentia Biological marker Biological activity Medicinal plant Vertebrata Mammalia Mouse Dicotyledones Animal Angiospermae Plant origin Ziziphus Euphorbiaceae Spermatophyta Contraceptive Estrous cycle Rhamnaceae |
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| References | Varley, H., 1969. Determination of blood urea by urease nesslarization method. In: Practical Clinical Biochemistry, 4th ed. White Herrers Press Ltd., London, 158 pp. Souleles, Shammas (BIB21) 1998; 59 Litchfield, Wilcoxon (BIB13) 1949; 96 Porras-Reyes, Lewis, Roman, Simchowitz, Mustoe (BIB17) 1993; 203 Tamooki, Pincus (BIB23) 1961; 69 Cai, Evans, Roberts, Phillipson, Zenk, Gleba (BIB6) 1991; 30 Guillemin, Sakiz (BIB9) 1963; 72 Kokwaro (BIB12) 1981; 123 Armstrong (BIB3) 1982; 93 Suzuki, Endo, Tanaka, Lizuka (BIB22) 1984; 148 Lohr, G.W., Waller, H.D., 1974. Glucose-6-phosphate dehydrogenase. In: Bergmeyer, H.U. (Ed.), Methods of Enzymatic Analysis, vol. 2. Verlag Chemie, Florida, pp. 636–643. Omaye, S.T., Turnbull, J.D., Souberlich, H.E., 1979. Selected methods for determination of ascorbic acid in animal cells, tissues and fluids. In: Mc Cormick, D.B., Wright, L.D. (Eds.), Methods in Enzymology, vol. 62. Academic Press, New York, pp. 3–47. Woo, Kang, Wagner, Seligmann, Chari (BIB26) 1980; 19 Ramirez, McCann (BIB20) 1964; 74 Woo, Shin, Kang (BIB27) 1980; 11 Rama Rao, N., Henry, A.N., 1997. Ethnobotany of Easternghats of Andhra Pradesh. Botanical Survey of India, Kolkata, India, pp. 68, 150. Astoor, A., King, E.J., 1954. Simplified colorimetric blood sugar method. Biochemical Journal 56, 1514. Zlatkis, Zak, Boyle (BIB28) 1953; 41 Anderson, McShan (BIB2) 1996; 78 Baillie, A.H., Fergusson, M.M., McHart, D., 1960. In: Developments in Steroid Biochemistry. Academic Press, New York, pp. 10–25. Wiest, Wilcox, Kirschbuam (BIB25) 1963; 73 Erenmemisoglu, Keletimur, Koker, Utsuol, Tekol, Ustdal (BIB8) 1995; 47 Zilversmist, Davis, Hamphenstern (BIB29) 1950; 35 Hermandez, Delgado (BIB10) 1992; 63 Kingsley, Roscoe (BIB11) 1949; 180 Rabin, Leipsner, Deane (BIB18) 1961; 69 Ambasta, S.P., 1986. Useful Plants of India. Publications and Information Directorate, CSIR, New Delhi, India, 703 pp. Lowry, Rosenbrough, Farm, Randall (BIB15) 1951; 193 Crossby, Munn, Furth (BIB7) 1954; 5 Cai (10.1016/j.jep.2003.09.002_BIB6) 1991; 30 Litchfield (10.1016/j.jep.2003.09.002_BIB13) 1949; 96 Porras-Reyes (10.1016/j.jep.2003.09.002_BIB17) 1993; 203 Rabin (10.1016/j.jep.2003.09.002_BIB18) 1961; 69 Kokwaro (10.1016/j.jep.2003.09.002_BIB12) 1981; 123 Ramirez (10.1016/j.jep.2003.09.002_BIB20) 1964; 74 Suzuki (10.1016/j.jep.2003.09.002_BIB22) 1984; 148 Guillemin (10.1016/j.jep.2003.09.002_BIB9) 1963; 72 Erenmemisoglu (10.1016/j.jep.2003.09.002_BIB8) 1995; 47 Zilversmist (10.1016/j.jep.2003.09.002_BIB29) 1950; 35 10.1016/j.jep.2003.09.002_BIB5 Lowry (10.1016/j.jep.2003.09.002_BIB15) 1951; 193 Anderson (10.1016/j.jep.2003.09.002_BIB2) 1996; 78 10.1016/j.jep.2003.09.002_BIB1 10.1016/j.jep.2003.09.002_BIB4 Crossby (10.1016/j.jep.2003.09.002_BIB7) 1954; 5 Souleles (10.1016/j.jep.2003.09.002_BIB21) 1998; 59 Hermandez (10.1016/j.jep.2003.09.002_BIB10) 1992; 63 Armstrong (10.1016/j.jep.2003.09.002_BIB3) 1982; 93 10.1016/j.jep.2003.09.002_BIB16 10.1016/j.jep.2003.09.002_BIB14 Wiest (10.1016/j.jep.2003.09.002_BIB25) 1963; 73 Woo (10.1016/j.jep.2003.09.002_BIB26) 1980; 19 Tamooki (10.1016/j.jep.2003.09.002_BIB23) 1961; 69 Woo (10.1016/j.jep.2003.09.002_BIB27) 1980; 11 10.1016/j.jep.2003.09.002_BIB19 Zlatkis (10.1016/j.jep.2003.09.002_BIB28) 1953; 41 Kingsley (10.1016/j.jep.2003.09.002_BIB11) 1949; 180 10.1016/j.jep.2003.09.002_BIB24 |
| References_xml | – volume: 74 start-page: 814 year: 1964 end-page: 816 ident: BIB20 article-title: Fluctuations in plasma luteinizing hormone concentrations during the estrus cycle of the rat publication-title: Endocrinology contributor: fullname: McCann – volume: 203 start-page: 18 year: 1993 end-page: 25 ident: BIB17 article-title: Enhancement of wound healing by the alkaloid taspine defining mechanism of action publication-title: Proceedings of Society for Experimental Biology and Medicine contributor: fullname: Mustoe – volume: 148 start-page: 76 year: 1984 end-page: 85 ident: BIB22 article-title: Indirect immunofluroescence studies on the steroid producing activity of hamster ova publication-title: American Journal of Obstretics and Gynecology contributor: fullname: Lizuka – volume: 19 start-page: 2791 year: 1980 end-page: 2793 ident: BIB26 article-title: Structure of flavone-C-glycoside from the seeds of publication-title: Phytochemistry contributor: fullname: Chari – volume: 69 start-page: 619 year: 1961 end-page: 625 ident: BIB18 article-title: A rapid sensitive assay procedure for adrenal steroid 3 OL dehydrogenase activity publication-title: Endocrinology contributor: fullname: Deane – volume: 41 start-page: 486 year: 1953 end-page: 492 ident: BIB28 article-title: A new method for the direct determination of serum cholesterol publication-title: Journal of Laboratory Clinical Medicine contributor: fullname: Boyle – volume: 35 start-page: 155 year: 1950 end-page: 160 ident: BIB29 article-title: Micro determination of plasma phospholipid by trichloroacetic acid precipitation method publication-title: Journal of Laboratory Clinical Investigation contributor: fullname: Hamphenstern – volume: 5 start-page: 695 year: 1954 end-page: 703 ident: BIB7 article-title: Standardizing a method for clinical haemoglobinometry publication-title: US Armed Force Medical Journal contributor: fullname: Furth – volume: 180 start-page: 315 year: 1949 end-page: 328 ident: BIB11 article-title: Determination of free and total cholesterol by direct chloroform extraction publication-title: Journal of Biological Chemistry contributor: fullname: Roscoe – volume: 123 start-page: 149 year: 1981 end-page: 152 ident: BIB12 article-title: A review of research on plants for fertility regulation in Africa publication-title: Korean Journal of Pharmacognosy contributor: fullname: Kokwaro – volume: 93 start-page: 415 year: 1982 end-page: 421 ident: BIB3 article-title: 3-β-Hydroxy-Δ-5-steroid dehydrogenase activity in the rapidly growing ovarian follicles of the domestic fowl ( publication-title: Journal of Endocrinology contributor: fullname: Armstrong – volume: 63 start-page: 373 year: 1992 end-page: 377 ident: BIB10 article-title: Terpenoids from aerial parts publication-title: Fitoterapia contributor: fullname: Delgado – volume: 30 start-page: 2033 year: 1991 end-page: 2040 ident: BIB6 article-title: Polyphenolic compounds from publication-title: Phytochemistry contributor: fullname: Gleba – volume: 47 start-page: 72 year: 1995 end-page: 74 ident: BIB8 article-title: Hypoglycemic activity of publication-title: Journal of Pharmacy and Pharmacology contributor: fullname: Ustdal – volume: 72 start-page: 813 year: 1963 end-page: 816 ident: BIB9 article-title: Quantitative study of responses to LH after hypophysectomy in the ovarian ascorbic acid depletion test: effect of prolactin publication-title: Endocrinology contributor: fullname: Sakiz – volume: 96 start-page: 99 year: 1949 end-page: 133 ident: BIB13 article-title: A simplified of evaluating dose-effect experiments publication-title: Pharmacological and Experimental Therapeutics. contributor: fullname: Wilcoxon – volume: 69 start-page: 527 year: 1961 end-page: 533 ident: BIB23 article-title: Biogenesis of progesterone in ovarian tissues publication-title: Endocrinology contributor: fullname: Pincus – volume: 59 start-page: 154 year: 1998 end-page: 156 ident: BIB21 article-title: Flavonoids from the leaves of publication-title: Fitoterapia contributor: fullname: Shammas – volume: 193 start-page: 265 year: 1951 end-page: 275 ident: BIB15 article-title: Protein measurement with folin-phenol reagent publication-title: Journal of Biological Chemistry contributor: fullname: Randall – volume: 73 start-page: 588 year: 1963 end-page: 595 ident: BIB25 article-title: Rat ovarian 20-alpha-hydroxysteroid-dehydrogenase: effects of estrogens and pituitary gonadotrophins publication-title: Endocrinology contributor: fullname: Kirschbuam – volume: 78 start-page: 976 year: 1996 end-page: 982 ident: BIB2 article-title: Luteinizing hormone levels in pig, cow and rat blood plasma during estrus cycle publication-title: Endocrinology contributor: fullname: McShan – volume: 11 start-page: 141 year: 1980 end-page: 148 ident: BIB27 article-title: Chemistry and pharmacology of flavone-C-glycosides from publication-title: Korean Journal of Pharmacognosy contributor: fullname: Kang – volume: 30 start-page: 2033 year: 1991 ident: 10.1016/j.jep.2003.09.002_BIB6 article-title: Polyphenolic compounds from Croton lechleri publication-title: Phytochemistry doi: 10.1016/0031-9422(91)85063-6 contributor: fullname: Cai – volume: 69 start-page: 527 year: 1961 ident: 10.1016/j.jep.2003.09.002_BIB23 article-title: Biogenesis of progesterone in ovarian tissues publication-title: Endocrinology doi: 10.1210/endo-69-3-527 contributor: fullname: Tamooki – volume: 47 start-page: 72 year: 1995 ident: 10.1016/j.jep.2003.09.002_BIB8 article-title: Hypoglycemic activity of Zizyphus jujuba publication-title: Journal of Pharmacy and Pharmacology doi: 10.1111/j.2042-7158.1995.tb05737.x contributor: fullname: Erenmemisoglu – ident: 10.1016/j.jep.2003.09.002_BIB19 – ident: 10.1016/j.jep.2003.09.002_BIB14 doi: 10.1016/B978-0-12-091302-2.50026-8 – volume: 63 start-page: 373 year: 1992 ident: 10.1016/j.jep.2003.09.002_BIB10 article-title: Terpenoids from aerial parts Croton draco publication-title: Fitoterapia contributor: fullname: Hermandez – volume: 11 start-page: 141 year: 1980 ident: 10.1016/j.jep.2003.09.002_BIB27 article-title: Chemistry and pharmacology of flavone-C-glycosides from Zizyphus seeds publication-title: Korean Journal of Pharmacognosy contributor: fullname: Woo – volume: 78 start-page: 976 year: 1996 ident: 10.1016/j.jep.2003.09.002_BIB2 article-title: Luteinizing hormone levels in pig, cow and rat blood plasma during estrus cycle publication-title: Endocrinology doi: 10.1210/endo-78-5-976 contributor: fullname: Anderson – volume: 73 start-page: 588 year: 1963 ident: 10.1016/j.jep.2003.09.002_BIB25 article-title: Rat ovarian 20-alpha-hydroxysteroid-dehydrogenase: effects of estrogens and pituitary gonadotrophins publication-title: Endocrinology doi: 10.1210/endo-73-5-588 contributor: fullname: Wiest – ident: 10.1016/j.jep.2003.09.002_BIB4 – volume: 59 start-page: 154 year: 1998 ident: 10.1016/j.jep.2003.09.002_BIB21 article-title: Flavonoids from the leaves of Zizyphus jujuba publication-title: Fitoterapia contributor: fullname: Souleles – ident: 10.1016/j.jep.2003.09.002_BIB24 – volume: 93 start-page: 415 year: 1982 ident: 10.1016/j.jep.2003.09.002_BIB3 article-title: 3-β-Hydroxy-Δ-5-steroid dehydrogenase activity in the rapidly growing ovarian follicles of the domestic fowl (Gallus domesticus) publication-title: Journal of Endocrinology doi: 10.1677/joe.0.0930415 contributor: fullname: Armstrong – volume: 35 start-page: 155 year: 1950 ident: 10.1016/j.jep.2003.09.002_BIB29 article-title: Micro determination of plasma phospholipid by trichloroacetic acid precipitation method publication-title: Journal of Laboratory Clinical Investigation contributor: fullname: Zilversmist – volume: 203 start-page: 18 year: 1993 ident: 10.1016/j.jep.2003.09.002_BIB17 article-title: Enhancement of wound healing by the alkaloid taspine defining mechanism of action publication-title: Proceedings of Society for Experimental Biology and Medicine doi: 10.3181/00379727-203-43567 contributor: fullname: Porras-Reyes – volume: 74 start-page: 814 year: 1964 ident: 10.1016/j.jep.2003.09.002_BIB20 article-title: Fluctuations in plasma luteinizing hormone concentrations during the estrus cycle of the rat publication-title: Endocrinology doi: 10.1210/endo-74-5-814 contributor: fullname: Ramirez – volume: 19 start-page: 2791 year: 1980 ident: 10.1016/j.jep.2003.09.002_BIB26 article-title: Structure of flavone-C-glycoside from the seeds of Zizyphus jujuba publication-title: Phytochemistry doi: 10.1016/S0031-9422(00)83976-X contributor: fullname: Woo – volume: 41 start-page: 486 year: 1953 ident: 10.1016/j.jep.2003.09.002_BIB28 article-title: A new method for the direct determination of serum cholesterol publication-title: Journal of Laboratory Clinical Medicine contributor: fullname: Zlatkis – volume: 193 start-page: 265 year: 1951 ident: 10.1016/j.jep.2003.09.002_BIB15 article-title: Protein measurement with folin-phenol reagent publication-title: Journal of Biological Chemistry doi: 10.1016/S0021-9258(19)52451-6 contributor: fullname: Lowry – volume: 148 start-page: 76 year: 1984 ident: 10.1016/j.jep.2003.09.002_BIB22 article-title: Indirect immunofluroescence studies on the steroid producing activity of hamster ova publication-title: American Journal of Obstretics and Gynecology doi: 10.1016/S0002-9378(84)80036-8 contributor: fullname: Suzuki – volume: 180 start-page: 315 year: 1949 ident: 10.1016/j.jep.2003.09.002_BIB11 article-title: Determination of free and total cholesterol by direct chloroform extraction publication-title: Journal of Biological Chemistry doi: 10.1016/S0021-9258(18)56747-8 contributor: fullname: Kingsley – volume: 123 start-page: 149 year: 1981 ident: 10.1016/j.jep.2003.09.002_BIB12 article-title: A review of research on plants for fertility regulation in Africa publication-title: Korean Journal of Pharmacognosy contributor: fullname: Kokwaro – volume: 72 start-page: 813 year: 1963 ident: 10.1016/j.jep.2003.09.002_BIB9 article-title: Quantitative study of responses to LH after hypophysectomy in the ovarian ascorbic acid depletion test: effect of prolactin publication-title: Endocrinology doi: 10.1210/endo-72-5-813 contributor: fullname: Guillemin – ident: 10.1016/j.jep.2003.09.002_BIB16 doi: 10.1016/0076-6879(79)62181-X – volume: 96 start-page: 99 year: 1949 ident: 10.1016/j.jep.2003.09.002_BIB13 article-title: A simplified of evaluating dose-effect experiments publication-title: Pharmacological and Experimental Therapeutics. contributor: fullname: Litchfield – ident: 10.1016/j.jep.2003.09.002_BIB5 – volume: 69 start-page: 619 year: 1961 ident: 10.1016/j.jep.2003.09.002_BIB18 article-title: A rapid sensitive assay procedure for adrenal steroid 3 OL dehydrogenase activity publication-title: Endocrinology doi: 10.1210/endo-69-3-619 contributor: fullname: Rabin – ident: 10.1016/j.jep.2003.09.002_BIB1 – volume: 5 start-page: 695 year: 1954 ident: 10.1016/j.jep.2003.09.002_BIB7 article-title: Standardizing a method for clinical haemoglobinometry publication-title: US Armed Force Medical Journal contributor: fullname: Crossby |
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| Snippet | The chloroform extract of
Croton roxburghii bark (CECR, Euphorbiaceae) and ethyl acetate extract of
Zizyphus jujuba bark (EAZJ, Rhamnaceae) were evaluated for... The chloroform extract of Croton roxburghii bark (CECR, Euphorbiaceae) and ethyl acetate extract of Zizyphus jujuba bark (EAZJ, Rhamnaceae) were evaluated for... |
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| SubjectTerms | 3-Hydroxysteroid Dehydrogenases - antagonists & inhibitors Animals Antifertility Biological and medical sciences Biomarker enzymes Cholesterol - biosynthesis Cholesterol - blood Croton Croton roxburghii Estrus - drug effects Estrus - physiology Female General pharmacology Glucosephosphate Dehydrogenase - antagonists & inhibitors Hematological profiles India Lethal Dose 50 Medical sciences Medicine, Traditional Mice Ovary - drug effects Ovary - physiology Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Plant Bark Plant Extracts - pharmacology Plant Extracts - toxicity Plants, Medicinal Ziziphus Zizyphus jujuba |
| Title | Anti-steroidogenic activity of the two Indian medicinal plants in mice |
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