Characteristics of Rat Lumbar Vertebral Body Bone Mineral Density and Differential Segmental Responses to Sex Hormone Deficiency： a Clinical Multidetector Computed Tomography Study

• Published in: Biomedical and environmental sciences Vol. 25; no. 6; pp. 607 - 613
• Main Authors: DENG, Min, WANG, Yi Xiang, GRIFFITH, James F., LU, Gang, AHUJA, Anil T, POON, Wai S
• Format: Journal Article
• Language: English
• Published: China Elsevier B.V 01.12.2012; Department of Imaging and Interventional Radiology, Prince of Wales Hospital, the Chinese University of Hong Kong, Shatin, N.T. Hong Kong, China%Division of Neurosurgery, Department of Surgery, Prince of Wales Hospital, the Chinese University of Hong Kong, Shatin, N.T. Hong Kong, China
• Subjects: animal models; Animals; bone density; Bone Density - drug effects; Bone mineral density; bone resorption; computed tomography; Cortical bone; Female; females; Gonadal Steroid Hormones - deficiency; Gonadal Steroid Hormones - metabolism; Lumbar Vertebrae - physiology; Male; males; Orchiectomy; osteoporosis; Ovariectomy; Quantitative computed tomography; Rat; Rats; Sex Factors; Trabecular bone; Vertebra; 临床; 大鼠模型; 生长激素; 矿物密度; 缺乏症; 腰椎; 计算机断层扫描; 骨质疏松症; Quantitative computed tomography; Rat; Ovariectomy; Vertebra; Trabecular bone; Bone mineral density; Cortical bone; Orchiectomy

Objective To investigate sex hormone deficiency related osteoporosis and efficacy of different therapies. Methods Orchiectomized and ovariectomized rat models are used to investigate sex hormone deficiency related osteoporosis and efficacy of different therapies. A rat vertebral body can be longitud...