Glutamate oxaloacetate transaminase: A new key in the dysregulation of glutamate in migraine patients

• Published in: Cephalalgia Vol. 33; no. 14; pp. 1148 - 1154
• Main Authors: Campos, Francisco, Sobrino, Tomás, Pérez-Mato, María, Rodríguez-Osorio, Xiana, Leira, Rogelio, Blanco, Miguel, Mirelman, David, Castillo, José
• Format: Journal Article
• Language: English
• Published: London, England SAGE Publications 01.10.2013
• Subjects: Adult; Aspartate Aminotransferases - blood; Biomarkers - blood; Case-Control Studies; Female; Glutamic Acid - blood; Humans; Male; Migraine Disorders - blood; Migraine Disorders - diagnosis; Young Adult; migraine; glutamate oxaloacetate transaminase; Blood; glutamate

Objective Based on the capacity of the blood-resident enzyme glutamate oxaloacetate transaminase (GOT) to metabolize blood glutamate, our aim was to study the association of GOT activity with serum glutamate levels and clinical parameters in patients with migraine. Methods This case-control study in...