An ex vivo model of human skin photoaging induced by UVA radiation compatible with summer exposure in Brazil

• Published in: Journal of photochemistry and photobiology. B, Biology Vol. 221; p. 112255
• Main Authors: Saguie, Bianca Oliveira, Martins, Rayssa Lopes, Fonseca, Adenilson de Souza da, Romana-Souza, Bruna, Monte-Alto-Costa, Andréa
• Format: Journal Article
• Language: English
• Published: Lausanne Elsevier B.V 01.08.2021; Elsevier BV
• Subjects: Aging; Aging (artificial); Carcinogenesis; Carcinogens; Collagen; Compatibility; Dermis; DNA damage; Elastin; Epidermis; ex vivo model; Explants; Exposure; Human skin; Inflammation; Ozone layer; Ozonosphere; Photoaging; Radiation damage; Skin; Ultraviolet radiation; UVA radiation; Brazil; Human skin; UVA radiation; ex vivo model; Photoaging

Skin is the largest body organ and can be affected by several factors, such as ultraviolet (UV) radiation. UV radiation is subdivided in UVA, UVB and UVC according to the radiation wavelength. UVC radiation does not cross the ozone layer; UVB cause DNA damage and is closely related to carcinogenesis...